Ge discovery st pet ct

Manufactured by GE Healthcare

The GE Discovery ST PET/CT is a diagnostic imaging system that combines positron emission tomography (PET) and computed tomography (CT) technologies. It is designed to capture high-resolution images of the body's anatomy and function.

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Lab products found in correlation

Gemini tf, by Philips (1 mentions)

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GE Discovery ST PET Discovery ST PET/CT GE Discovery ST Discovery ST

2 protocols using ge discovery st pet ct

FDG PET/CT Imaging of Multiple Myeloma

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All newly diagnosed MM patients underwent a PET/CT according to the current IMWG guidelines^{38 (link)}. Imaging was performed on a GE Discovery ST PET/CT (GE Healthcare, Chicago, IL). Approximately 60 min after the intravenous administration of 10 mCi of 18F-fluorodeoxyglucose (FDG) a low-dose, non-contrast, diagnostic quality whole-body CT was performed for assessment of bone disease, attenuation correction and anatomic orientation. Axial images were reconstructed at 3.75 mm. Afterwards a PET covering the same anatomical regions was obtained and reconstructed with and without attenuation correction. Interpretation was performed according to the Interpretation criteria for FDG PET/CT in multiple myeloma (IMPeTUs)³⁹. OL were characterized by the presence of circumscribed areas with bone loss. Increased tracer uptake was graded according to the 5-point Deauville scoring system³⁹.

Merz M., Merz A.M., Wang J., Wei L., Hu Q., Hutson N., Rondeau C., Celotto K., Belal A., Alberico R., Block A.W., Mohammadpour H., Wallace P.K., Tario J., Luce J., Glenn S.T., Singh P., Herr M.M., Hahn T., Samur M., Munshi N., Liu S., McCarthy P.L, & Hillengass J. (2022). Deciphering spatial genomic heterogeneity at a single cell resolution in multiple myeloma. Nature Communications, 13, 807.

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18F-FDG PET/CT Imaging Protocol

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¹⁸F-FDG PET/CT images were performed following a 4-hour fast and blood glucose level < 125 mg/dl, PET/CT. Imaging was performed ~ 1 hour post injection of 10–15 mCi [375–555 MBq] of ¹⁸F-FDG i.v. Eleven patients were imaged using a 3-dimensional (3D) Time-of-Flight (TOF) mode Gemini TF (Philips Medical Systems, Andover, MA, USA). The remaining 10 patients were imaged on a GE Discovery ST PET/CT, (General Electric Medical Systems, Milwaukee, WI). A low dose, non-contrast, CT transmission scan (120 kVp, 60mAs) was used for attenuation correction and co-registration purposes. To normalize for possible individual scanner quantitative SUV value differences, a tumor: mediastinal blood pool ratio was also performed. All tumors were visible over background. All tumors had ¹⁸F-FDG SUV_est.max. value >2, and had a minimum tumor:mediastinal blood pool value of 1.4.

Mena E., Lindenberg M.L., Turkbey B.I., Shih J., Logan J., Adler S., Wong K., Wilson W., Choyke P.L, & Kurdziel K. (2014). A pilot study of the value of 18F-Fluoro-deoxy-thymidine (18F-FLT) PET/CT in predicting viable lymphoma in residual 18F-FDG avid masses following completion of therapy. Clinical nuclear medicine, 39(10), 874-881.

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