Ronidazole

Manufactured by Merck Group

Sourced in United States

Ronidazole is a laboratory reagent used in the chemical and pharmaceutical research industries. It is a nitroimidazole compound with antimicrobial properties. Ronidazole is commonly used as a research tool in various scientific applications, but its core function is to serve as a reference standard or active ingredient in laboratory experiments and analyses. A detailed description of its intended use or application is not provided to maintain an unbiased and factual approach.

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Lab products found in correlation

3 protocols using ronidazole

Reagent Sources for Immunoassay Development

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NIC, 4-nitroaniline, 2-nitroaniline, 3-nitroaniline, N-(4-nitrophenyl) propionamide, H-Val-pNA HCl, L-argininep-nitroanilide dihydrochloride, 4-nitrophenethylamine hydrochloride, N-methyl-4-nitrophenethylamine hydrochloride, H-Ala-pNA HCl, N, N-dimethyl-4-nitroaniline, H-Glu-pNA, halofuginone, toltrazuril, 1,3-diphenylguanidine, ronidazole, and dinitolmide were obtained from Sigma-Aldrich (St. Louis, MO, USA) (Figure 1). The coating antigen (DNC-4-BSA) and mAb 3B4 were acquired from China Agricultural University (Qianqian Tang May 2018). For other reagents materials were shown in the Supplementary Materials part.

Zou M., Yin Y., Guo L., Zhang Q., Li J., Zhang H., Song Q., Li Z., Wang L., Ao X, & Liang X. (2023). A Europium Nanosphere-Based Time-Resolved Fluorescent Immunochromatographic Assay for the Rapid Screening of 4,4′-Dinitrocarbanilide: Aiming at Improving Strip Method Performance. Biosensors, 13(5), 518.

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Comprehensive Veterinary Drug Extraction

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All solvents (HPLC/analytical grade) were purchased from Fluka (Sigma- Aldrich, St. Louis, MO, USA). Trichloroacetic acid (TCA) crystals and the reagents to prepare an EDTA-McIlvaine buffer solution, pH 4 (disodium hydrogen phosphate dihydrate, citric acid monohydrate and EDTA) were purchased from Fluka.
Formic acid (98–100%) was obtained from Riedel-de Haën (Sigma-Aldrich, St. Louis, MO, USA).
The extraction cartridges (Oasis HLB 3 mL, 60 mg) were provided by Waters (Milford, MA, USA).Amoxicillin, ampicillin, benzylpenicillin, cefalexin, cefquinome, ceftiofur, chloramphenicol, chlortetracycline, ciprofloxacin, danofloxacin, dimetridazole, doxycycline, enrofloxacin, florfenicol, florfenicol amine, flumequine, furaltadone, furazolidone, lincomycin, lomefloxacin hydrochloride, marbofloxacin, nalidixic acid, nitrofurazone, oxolinic acid, oxytetracycline, ronidazole, spyramicin, sulphadiazine, sulphadimethoxine, sulphadimidine, sulphamerazine, sulphathiazole, tetracycline hydrochloride, thiamphenicol, tilmicosine, tinidazole, trimethoprim, tylosin, and enrofloxacin d5 as the internal standards (IS) (purity >98%) were used and purchased from Fluka (Sigma-Aldrich, St. Louis, MO, USA).

Savarino A.E., Terio V., Barrasso R., Ceci E., Panseri S., Chiesa L.M, & Bonerba E. (2020). Occurrence of antibiotic residues in Apulian honey: potential risk of environmental pollution by antibiotics. Italian Journal of Food Safety, 9(1), 8678.

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Repositioning Compound Library Evaluation

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The Pharmakon 1600 repositioning compound library was purchased from
MicroSource Discovery Systems, Inc. (Gaylordsville, CT) and the Johns Hopkins
library was provided by Johns Hopkins University (Baltimore, MD). Both libraries
were supplied in 96-well plates of 10 mM stocks of the compounds in either
dimethyl sulfoxide or water and stored in −80° C. Ornidazole,
miconazole nitrate, econazole nitrate, tioconazole, butoconazole, clotrimazole,
metoprolol tartrate, metoclopramide hydrochloride, chloroquine diphosphate,
miconazole, dimetridazole, nithiamide and methylthiouracil (Alfa Aesar, Ward
Hill, MA), dichlorophen, triclabendazole, closantel, nitazoxanide (Ark Pharm
Inc, Libertyville, IL), ronidazole, oxyclozanide (Sigma-Aldrich, St. Louis, MO),
tinidazole (TCI, Portland, OR) and niclosamide (Cayman Chemical, Ann Arbor, MI)
were all purchased separately to confirm the results of both libraries.
Vancomycin hydrochloride (Gold Biotechnology, Olivette, MO) and metronidazole
(BTC, Hudson, NH) were used as positive controls.

AbdelKhalek A., Mohammad H., Mayhoub A.S, & Seleem M.N. (2020). Screening for potent and selective anticlostridial leads among FDA-approved drugs. The Journal of antibiotics, 73(6), 392-409.

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