Origin software version 8

Manufactured by OriginLab

Sourced in United States

Origin is a data analysis and graphing software package developed by OriginLab. Version 8.5 includes core functionalities for data import, plotting, analysis, and report generation. The software supports a wide range of data formats and provides tools for curve fitting, statistics, and signal processing.

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Lab products found in correlation

Actilyse, by Boehringer Ingelheim (2 mentions) Sas program version 8, by SAS Institute (2 mentions) Dade innovin, by Siemens (1 mentions) Spss 19, by IBM (1 mentions) Sas version 8, by SAS Institute (1 mentions) Spss software version 16, by IBM (1 mentions) Microcal vp itc, by Malvern Panalytical (1 mentions) Cary 360, by Agilent Technologies (1 mentions) Microcal itc200, by Malvern Panalytical (1 mentions) Illustrator cs6, by Adobe (1 mentions) Excel software, by IBM (1 mentions) Statistical package for social sciences 20, by IBM (1 mentions) Synergy 2 plate reader, by Bioteck (1 mentions)

Spelling variants of this product

Origin 8.0 (1499 citations) Origin software (583 citations) Origin version 8.0 (32 citations) Origin software 8.0 (6 citations) OriginLab version 8.0 (4 citations) Origin Lab software version 8.0 (2 citations)

29 protocols using origin software version 8

Triplicate Experiments with Origin Software

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All experiments were conducted in triplicate, leading to achieve the evaluation by the mean ± standard deviation (SD). The figures were plotted by Origin Software Version 8.5 (OriginLab Corp., MA, USA).

Wang D., Liu J., Qiu S., Wang J., Song G., Chu B., Li L., Xiao G., Gong J, & Zheng F. (2021). Ultrasonic degradation kinetics and isomerization of 3- and 4-O-caffeoylquinic acid at various pH: The protective effects of ascorbic acid and epigallocatechin gallate on their stability. Ultrasonics Sonochemistry, 80, 105812.

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Characterization of Nanomaterial Properties

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All the data are reported as mean±standard deviation. One-way ANOVA with Tukey’s post-hoc analysis was applied to check the difference in mean values. A P-value less than 0.05 was considered as significant. The statistical analysis was performed on Origin software version 8.5 (OriginLab, Northampton, MA).

Li A., Khan I.N., Khan I.U., Yousaf A.M, & Shahzad Y. (2021). Gellan Gum-Based Bilayer Mucoadhesive Films Loaded with Moxifloxacin Hydrochloride and Clove Oil for Possible Treatment of Periodontitis. Drug Design, Development and Therapy, 15, 3937-3952.

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Statistical Analysis of Normalized Means

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Values are given as normalized means and standard deviation of the mean. Statistical comparisons intragroup and between groups were performed with t test using Origin software version 8.5 (OriginLab, Northampton, MA), after submitting data to Levenne and Shapiro-Wilk tests to confirm homogeneity and normality. Results were considered significant if p<0.05.

Sabino C.P., Garcez A.S., Núñez S.C., Ribeiro M.S, & Hamblin M.R. (2014). Real-time evaluation of two light delivery systems for photodynamic disinfection of Candida albicans biofilm in curved root canals. Lasers in medical science, 30(6), 1657-1665.

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Comparative Analysis of Protein Levels

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Values are provided as mean and standard deviation. Statistical comparisons within and between groups were performed with t test using Origin software version 8.5 (OriginLab, Northampton, MA, USA) after submitting data to Levenne and Shapiro-Wilk tests to confirm homogeneity and normality. Results were considered significant if P<0.05.

GARCEZ A.S, & HAMBLIN M.R. (2017). Methylene Blue and Hydrogen Peroxide for Photodynamic Inactivation in Root Canal - A New Protocol for Use in Endodontics. European endodontic journal, 2(1), 29.

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Plasma Fibrinolytic Potential Assay

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Plasma fibrinolytic potential was determined using a turbidity assay.^{28 (link)} tPA (80 ng/mL tPA; Actilyse, Boehringer Ingelheim, Ingelheim, Germany) was added to plasma containing 17 mmol/L CaCl₂, tissue factor (TF) (1,750 × diluted TF; Dade Innovin, Siemens Healthcare Diagnostics Inc., Marburg, Germany) and 10 mmol/L phospholipid vesicles (Rossix, Mölndal, Sweden). The tPA and TF concentrations were selected to obtain CLTs between 60 and 100 minutes. To determine clotting and lysis times from the resultant curves, sigmoidal curve fitting was used (Origin software version 8.5 [Origin lab, 2010]). Lag time (minutes), slope (×10⁻³ au/s), maximum absorbance (Δau), and CLT (minutes) were calculated as previously described.^{6 (link)}

Pieters M., Guthold M., Nunes C.M, & de Lange Z. (2019). Interpretation and Validation of Maximum Absorbance Data Obtained from Turbidimetry Analysis of Plasma Clots. Thrombosis and haemostasis, 120(1), 44-54.

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Fibrinolytic Potential of Plasma Clots

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A modified turbidity assay [35 (link)] was used to determine formation, structure, and fibrinolytic potential of plasma clots. Final concentrations were 80 ng/mL tissue plasminogen activator (tPA; Actilyse, Boehringer Ingelheim, Ingelheim, Germany), 17 mM CaCl₂, 1750× diluted tissue factor (TF; Dade Innovin, Siemens Healthcare Diagnostics Inc., Marburg, Germany) and 10 mM phospholipid vesicles (Rossix, Mölndal, Sweden). The TF and tPA concentrations were selected to obtain clot lysis times (CLTs) between 60 and 100 min in control plasma. Sigmoidal curve fitting [Origin^® software version 8.5 (Origin lab^®, 2010)] was used to determine clot lysis time (CLT). Lag time (minutes), slope (×10⁻³ au/s), and maximum absorbance (Δau) were calculated as previously described [34 (link)].

Daraei A., Pieters M., Baker S.R., de Lange-Loots Z., Siniarski A., Litvinov R.I., Veen C.S., de Maat M.P., Weisel J.W., Ariëns R.A, & Guthold M. (2021). Automated Fiber Diameter and Porosity Measurements of Plasma Clots in Scanning Electron Microscopy Images. Biomolecules, 11(10), 1536.

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Data Analysis Software Utilization

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The data processing and graphical representations were conducted using Origin software version 8.5 (OriginLab Corp., MA, USA). Statistical analyses were performed using SPSS 19.0 (IBM Inc., Chicago, IL, USA) with a significance level of P < 0.05.

Yang Q., Guo J., Zhang F., Zhao F, & Zhang G. (2024). Inulin with different degrees of polymerization as a functional ingredient: Evaluation of flour, dough, and steamed bread characteristics during freezing. Food Chemistry: X, 22, 101431.

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Anlotinib's Effects on OSA Cells

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Statistical analysis was performed by Bonferroni’s correction with or without two-way ANOVA methods using SPSS (Version No. 8.0; IBM Corporation, Armonk, NY, USA). The IC₅₀ values of anlotinib on OSA cells were calculated by Origin Software, version 8.5 (OriginLab, Northampton, MA, USA). A P-value of <0.05 was considered statistically significant between the results from two groups.

Wang L., En H., Yang L., Zhang Y., Sun B, & Gao J. (2019). miR-596 suppresses the expression of Survivin and enhances the sensitivity of osteosarcoma cells to the molecular targeting agent anlotinib. OncoTargets and therapy, 12, 6825-6838.

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Triplicates ANOVA Analysis with Origin

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Unless otherwise specified, all experiments in this study were performed in triplicates. An analysis of variance (ANOVA) was carried out using the SAS program version 8.1 (SAS Institute Inc., Cary, NC, USA). The least significant difference (LSD) was computed at p < 0.05. All figures were drawn using Origin software version 8.5 (Origin Lab Corp., Northampton, MA, USA). Error bars denote standard deviation of the mean.

Xu J.M., Li J.Q., Zhang B., Liu Z.Q, & Zheng Y.G. (2019). Fermentative production of the unnatural amino acid l-2-aminobutyric acid based on metabolic engineering. Microbial Cell Factories, 18, 43.

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Comparative Analysis of Protein Levels

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Garcez A.S, & Hamblin M.R. (2017). Methylene Blue and Hydrogen Peroxide for Photodynamic Inactivation in Root Canal - A New Protocol for Use in Endodontics. European Endodontic Journal, 2(1), 1-7.

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