All the patients were assessed with hypophysis MRI before the procedure. MRI examinations were performed using the same hypophysis MRI protocol using the 1.5-T Siemens MR unit (Magnetom Symphony Quantum, Siemens Medical Systems Erlangen, Germany) or 1.5-T Philips MR unit (Achieva; Philips Healthcare, Best, the Netherlands). T1-weighted and T2-weighted spin echo sequences were obtained with a slice thickness of 3 mm at the coronal and sagittal planes. Later, T1-weighted turbo spin echo dynamic sequences were obtained with 3-mm slice thickness at the coronal and sagittal plans after gadolinium injection (0.1 mmol/kg). IPSS was planned for the patients who were not found to have pituitary gland adenoma or who were found to have adenoma with a diameter <6 mm.
Magnetom symphony quantum
Manufactured by Siemens
Sourced in Germany
The Magnetom Symphony Quantum is a magnetic resonance imaging (MRI) system manufactured by Siemens. It is designed to acquire high-quality images of the human body for diagnostic purposes. The system utilizes a superconducting magnet and advanced imaging techniques to capture detailed anatomical information without the use of ionizing radiation.
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7 protocols using magnetom symphony quantum
1
Pituitary MRI and IPSS Evaluation
2
Pituitary MRI Imaging Protocol
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MRI examinations were performed using the same pituitary MRI protocol for all patients with a 1.5-T Siemens MR unit (Magnetom Symphony Quantum, Siemens Medical Systems) or 1.5-T Philips MR unit (Achieva; Philips Healthcare). T1-weighted and T2-weighted spin echo sequences were obtained with a slice thickness of 3 mm for the coronal and sagittal planes. Later, T1-weighted turbo spin echo dynamic sequences were obtained with 3-mm slice thickness for the coronal and sagittal planes after gadolinium injection (0.1 mmol/kg).
3
Quantifying Myocardial Scar Using Cardiac MRI
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Cardiac MRI was performed in all patients using a 1.5 Tesla scanner (Magnetom Symphony Quantum; Siemens Medical Systems, Erlangen, Germany), after intravenous injection of gadopentetate dimeglumine 0.2 mmol/kg (Magnevist; Bayer HealthCare AG, Leverkusen, Germany). LE images were obtained with T1 inversion recovery sequences (8‐mm slice thickness, breath hold, field of view 240×320 mm2, matrix size 165×256, repetition time 7.5 ms, echo time 3.4 ms, and flip angle 258). Areas with pathological mid‐ or transmural LE were measured manually in the basal, mid, and apical segments, covering the entire ventricle using continuous short‐axis views. The sum of all enhanced areas was multiplied by the slice thickness and then set in relation to the LV myocardial volume. With this technique, every LV segment was scanned separately for occurrence of pathological LE. Attention was paid to a similar setting for the follow‐up scan.
4
Cardiac MRI Protocol for Ventricular Mass
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Cardiac magnetic resonance imaging was performed using a 1.5T MRI (Magnetom Symphony Quantum, Siemens Healthineers, Erlangen, Germany) with a 12-channel body phased-array coil (6 elements in the front and 6 elements in the back integrated into the spine-array). An electrocardiogram-gated balanced steady-state free precession technique (TR, 4.3 ms; TE, 2.15 ms; flip angle, 70°; temporal resolution <50 ms) was used for morphologic imaging. For the analysis of LV mass and volumes, short-axis views were acquired (10–12 consecutive 8-mm slices, depending on heart size). For assessment of the aortic supravalvular area, including the ascending aorta, the same sequence was planned in the 3-chamber view (3CV).
5
Gadopentetate Dimeglumine-Enhanced Cardiac MRI
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CMRI was performed after intravenous injection of gadopentetate dimeglumine 0.2 mmol/kg (Magnevist®, Bayer Schering Pharma AG, Berlin, Germany)on a 1.5 Tesla scanner (Magnetom Symphony Quantum, Siemens AG Healthcare Sector, Erlangen, Germany). Pictures were acquired with segmented inversion-recovery turboFLASH sequences (8 mm slice thickness, no slice spacing, breath hold technique, field of view 240 x 320 mm², matrix size 165 x 256, repetition time 7.5 ms, echo time 3.4 ms, flip angle 25° and acquisition window 250ms). The time of inversion (TI) was set to null normal myocardium (range 230-330ms). All consecutive short axis slices were used for manually tracing the area with pathological mid- or transmyocardial LE. The sum of areas was multiplied with the slice thickness and then set in relation to LV myocardium volume.
6
Vertebral MRI for Trauma Evaluation
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Conventional vertebral column MRI examinations were performed in all patients, using a 3.0 Tesla MRI apparatus (Siemens Magnetom Symphony Quantum, Erlangen, Germany) with a spine coil. Routine sequences studied in patients with trauma consisted of T1-weighted spin echo (SE), T2-weighted SE sagittal, T2-weighted SE axial, and STIR sagittal sections. All MRI examinations were performed within one week after trauma. According to a previous study, the linear black signal change was defined as a linear black signal area of more than half the length of the fractured vertebral body on STIR image [17 (link)] (Figure 2 ).
7
Late Gadolinium Enhancement CMR Protocol
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CMRI was performed with intravenous injection of gadobenate dimeglumine 0.1 mmol/kg (Multihance, Braco Diagnostics, Italy) on a 1.5-T scanner (Magnetom Symphony Quantum, Siemens Medical Systems, Erlangen, Germany). LE images were acquired with inverse recovery sequences (8 mm slice thickness, breath hold, field of view 240 × 320 mm 2 , matrix size 165 × 256, repetition time 7.5 ms, echo time 3.4 ms, flip angle 25°). Short axis views at the basal, mid and apical segments, covering the entire ventricle, were used. Applying this LE technique, every LV segment, using a standard 17-segment model, was evaluated for the occurrence of myocardial replacement fibrosis. Standard cine breath-hold short axis images were used to determine wall thickness, cardiac mass and ejection fraction. All cMRI data were analyzed by experienced investigators blinded to echocardiographic and clinical results.
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