2 methylhexanoic acid

Manufactured by Merck Group

Sourced in United States

2-methylhexanoic acid is a carboxylic acid with the chemical formula CH3CH2CH2CH2CH(CH3)COOH. It is a colorless, oily liquid with a characteristic odor. The compound is used as a chemical intermediate and in the synthesis of various organic compounds.

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Lab products found in correlation

2 protocols using 2 methylhexanoic acid

Fatty Acid Analysis Protocol

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Acetic acid was purchased from Thermo Fisher Scientific (Fair Lawn, NJ). Propionic acid, iso butyric acid, butyric acid, 2-methylbutyric acid, iso valeric acid, valeric acid, 2-methylpentanoic acid, 3-methylpentanoic acid, iso caproic acid, caproic acid, 2-methylhexanoic acid, 4-methylhexanoic acid, heptanoic acid, hexanoic acid-6,6,6-d₃ internal standard, N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA), and methoxyamine hydrochloride were purchased from Sigma-Aldrich (St. Louis, MO).

Zhang A., Matsushita M., Zhang L., Wang H., Shi X., Gu H., Xia Z, & Cui J.Y. (2021). Cadmium exposure modulates the gut-liver axis in an Alzheimer’s disease mouse model. Communications Biology, 4, 1398.

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Dose-Dependent Chemical Embryo Toxicity

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Except for 4-eneVPA (Santa Cruz Biotechnology, Dallas, Texas, USA; 98 % purity), all other chemicals (valproic acid, 2,2-dimethylvaleric acid, 2-ethylbutyric acid, 2-ethyl hexanoic acid, 2-methyl hexanoic acid, 2-methylpentanoic acid, 2-propylheptanoic acid, 4-pentenoic acid and hexanoic acid) were purchased at the highest purity available from Sigma (Deisenhofen, Germany). After initial rangefinding tests, the ten chemicals were tested at three to eight different concentrations prepared from a 100 % DMSO stock solutions (n = 3). Nominal and analytically measured water concentrations as well as measured total embryo concentrations are summarized in Table S1 of the Supporting Information. The highest concentration tested led sometimes to 100% mortality of the embryos. In such cases, no concentration measurement was made.

Siméon S., Brotzmann K., Fisher C., Gardner I., Silvester S., Maclennan R., Walker P., Braunbeck T, & Bois F.Y. (2020). Development of a generic zebrafish embryo PBPK model and application to the developmental toxicity assessment of valproic acid analogs. Reproductive toxicology (Elmsford, N.Y.), 93.

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