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Prism 5.0c software

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Prism 5.0c is a data analysis and graphing software developed by GraphPad. It is designed to help researchers and scientists quickly and easily analyze their data, create publication-quality graphs, and perform statistical analysis.

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Lab products found in correlation

Spss ver 20, by IBM (2 mentions) Imagequant 5, by GE Healthcare (1 mentions) Typhoon 8600, by GE Healthcare (1 mentions)

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GraphPad Prism 5 (39065 citations) Prism software (8870 citations) Prism software 5.0 (327 citations) Prism 5.0c (110 citations)

15 protocols using prism 5.0c software

1

Statistical Analysis of Survival Outcomes

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SPSS ver. 20.0 (IBM Co., Armonk, NY, USA) and Prism 5.0c software (GraphPad, La Jolla, CA, USA) were used for statistical analysis. PFS and OS were estimated with the Kaplan-Meier method of log-rank test. Median PFS and OS were calculated with the reverse Kaplan-Meier method. A multivariate analysis was performed with Cox proportional hazards model to determine risk factors after adjustment for known prognostic variables. Frequency distributions were compared with chi-square and Fisher's exact test, mean and median values in the groups were compared with the Mann-Whitney U-test. A p<0.05 was considered statistically significant.
Yang J., Shen K., Wang J., Yang J, & Cao D. (2016). Extrafascial hysterectomy after concurrent chemoradiotherapy in locally advanced cervical adenocarcinoma. Journal of Gynecologic Oncology, 27(4), e40.
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2

HIV-1 Integrase Gel-Based Assay

Cited 1 time
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HIV-1 IN gel-based assays were carried out as previously published.33 (link) Briefly, drugs or an equivalent volume of 100% DMSO (dimethyl sulfoxide, used as the drug solvent) was added to a reaction mixture containing 20 nM 32P-labeled DNA substrate and 400 nM IN in 50 mM MOPS, pH 7.2, 7.5 mM MgCl2, and 14 mM 2-mercaptoethanol. Reactions were performed at 37 °C for 1 h and stopped by the addition of an equal volume of loading buffer [formamide containing 1% SDS (sodium dodecyl sulfate), 0.25% bromophenol blue, and xylene cyanol]. Products were separated in 16% polyacrylamide denaturing sequencing gels. Dried gels were visualized using a Typhoon 8600 (GE Healthcare). Densitometric analyses were performed using the ImageQuant 5.1 software from GE Healthcare. Data analyses (linear regression, IC50 determination, and standard deviation) were performed using Prism 5.0c software from GraphPad.
Pescatori L., Métifiot M., Chung S., Masoaka T., Crucitti G.C., Messore A., Pupo G., Madia V.N., Saccoliti F., Scipione L., Tortorella S., Di Leva F.S., Cosconati S., Marinelli L., Novellino E., Le Grice S.F., Pommier Y., Marchand C., Costi R, & Di Santo R. (2015). N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase. Journal of medicinal chemistry, 58(11), 4610-4623.
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3

Statistical Analysis of Biological Data

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Data were expressed as the means with 95% confidence intervals. Statistical analysis was performed with two tailed t-test or one-way analysis of variance (ANOVA) using Prism 5.0c Software (GraphPad Software, La Jolla, CA). For all results, statistical significance was defined by a value of P < 0.05.
Men K., Huang R., Zhang X., Zhang R., Zhang Y., Peng Y., Tong R., Yang L., Wei Y, & Duan X. (2018). Delivery of interleukin-22 binding protein (IL-22BP) gene by cationic micelle for colon cancer gene therapy. RSC Advances, 8(30), 16537-16548.
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4

Statistical Analysis of Biological Data

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Data were expressed as the means with 95% confidence intervals. Statistical analysis was performed with two tailed t-test or one-way analysis of variance (ANOVA) using Prism 5.0c Software (GraphPad Software, La Jolla, CA). For all results, statistical significance was defined by a value of P < 0.05.
Men K., Zhang R., Zhang X., Huang R., Zhu G., Tong R., Yang L., Wei Y, & Duan X. (2018). Delivery of modified mRNA encoding vesicular stomatitis virus matrix protein for colon cancer gene therapy. RSC Advances, 8(22), 12104-12115.
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5

Statistical Analysis of Endometrial Cancer

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SPSS ver. 20.0 (IBM Co., Armonk, NY, USA) and Prism 5.0c software (GraphPad, La Jolla, CA, USA) were used for statistical analysis. Data were documented as numbers and percentages unless otherwise noted. Continuous data were compared using Mann-Whitney U test. Frequency distributions were compared using χ2 test and Fisher's exact test for categorical variables. PFS and OS were estimated with the Kaplan-Meier method of log-rank test. Median PFS and OS were calculated with the reverse Kaplan-Meier method and log-rank test. The predictors of recurrence (age, histology type, grade, RD, margin, LVSI, cervical stromal invasion, parametrial invasion, lymphadenectomy) were assessed via univariate analyses. Major risk factors including lymph node metastasis, parametrium involvement, RD, LVSI, tumor size, stromal invasion and variable with significant p value in univariate analyses were included for multivariate analyses using the Cox proportional hazards model. The value of p<0.05 was considered significant.
Yang J., Yang J., Cao D., Shen K., Ma J, & Zhang F. (2019). Completion hysterectomy after chemoradiotherapy for locally advanced adeno-type cervical carcinoma: updated survival outcomes and experience in post radiation surgery. Journal of Gynecologic Oncology, 31(2), e16.
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6

Guinea Pig Ileum Pharmacology Assay

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Guinea
pigs of either sex (250–500 g) were stunned by a blow on the
neck and exsanguinated. The ileum was rapidly removed, rinsed, and
cut into segments of 1.5–2.0 cm length. The tissues were mounted
isotonically (preload of 5 mN) in a jacketed 20 mL organ bath that
was filled with Tyrode’s solution (composition [mM]: NaCl,
137; KCl, 2.7; CaCl2, 1.8; MgCl2, 1.0; NaH2PO4, 0.4; NaHCO3, 11.9; and glucose
5.0) supplemented with atropine, at a concentration not affecting
H1 receptors (0.05 μM), to block cholinergic muscarinic
receptors. The bath was aerated with 95% O2/5% CO2 and heated to 37 °C. During an equilibration period of 80 min,
the tissues were stimulated three times with histamine (2 × 1
μM, 1 × 10 μM) followed by washout. Up to four cumulative
CRCs were determined on each tissue: the first by addition of histamine
(0.01–30 μM) and the second to fourth by addition of
histamine in the presence of increasing concentrations of antagonist
(preincubation: 10–15 min). pEC50 differences were
not corrected because four successive curves for histamine were superimposable
under these conditions (N > 10). Data were analyzed
by nonlinear regression and were best-fitted to sigmoidal concentration–response
curves using Prism 5.0c software (GraphPad, San Diego, CA).
Pockes S., Wifling D., Keller M., Buschauer A, & Elz S. (2018). Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists. ACS Omega, 3(3), 2865-2882.
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7

Statistical Analysis of Experimental Data

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Data were expressed as means with 95% confidence intervals. Statistical analysis was performed using a two-tailed Student's t-test or one-way analysis of variance (ANOVA) using Prism 5.0c Software (GraphPad Software, La Jolla, CA). For all results, a statistically significant difference was defined by a value of * P < 0.05, **P < 0.01, ***P < 0.001.
Zhou T., Peng J., Hao Y., Shi K., Zhou K., Yang Y., Yang C., He X., Chen X, & Qian Z. (2020). The construction of a lymphoma cell-based, DC-targeted vaccine, and its application in lymphoma prevention and cure. Bioactive Materials, 6(3), 697-711.
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8

Statistical Analysis of Experimental Data

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Data were expressed as the means with 95% CIs. Statistical analysis was performed with two-tailed t-test or one-way ANOVA using Prism 5.0c Software (GraphPad Software, La Jolla, CA, USA). For all results, statistical significance was defined by a value of *P<0.05, **P<0.01, ***P<0.01.
Zhang X., Men K., Zhang Y., Zhang R., Yang L, & Duan X. (2019). Local and systemic delivery of mRNA encoding survivin-T34A by lipoplex for efficient colon cancer gene therapy. International Journal of Nanomedicine, 14, 2733-2751.
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9

Statistical Analysis of Research Data

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Statistical analysis was undertaken using Prism 5.0c Software. A two-tailed t-test or a one-way analysis of variance (ANOVA) was performed when comparing two groups or more than two groups, respectively. Statistical significance was defined by a value of P < 0.05. Data were shown as mean ± SD.
Miao L., Liu Q., Lin C.M., Luo C., Wang Y., Liu L., Yin W., Hu S., Kim W.Y, & Huang L. (2016). Targeting Tumor-associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors: ——In situ Generation of Tumor Suppressive Fibroblasts. Cancer research, 77(3), 719-731.
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10

Statistical Analysis of Experimental Data

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Statistical analysis was undertaken using Prism 5.0c Software. A two-tailed t-test or a one-way analysis of variance was performed when comparing two groups or more than 2 groups, respectively. Statistical significance was defined by a value of p < 0.05.
Miao L., Wang Y., Xiong Y., Lin C.M., Chen N., Zhang L., Kim W.Y, & Huang L. (2015). Nanoparticle Modulation of the Tumor Microenvironment Enhances Therapeutic Efficacy of Cisplatin. Journal of controlled release : official journal of the Controlled Release Society, 217, 27-41.
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