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Discovery 600 scanner

Manufactured by GE Healthcare
Sourced in United States

The Discovery 600 scanner is a medical imaging device developed by GE Healthcare. It is designed to capture high-quality images for diagnostic purposes. The scanner utilizes advanced imaging technology to produce detailed scans of the body's internal structures. The core function of the Discovery 600 is to provide healthcare professionals with the necessary imaging data to support their clinical decision-making processes.

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3 protocols using discovery 600 scanner

1

Dual-Tracer PET/CT Imaging Protocol

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PET/CT images were acquired with a Discovery 600 scanner (GE Healthcare, Milwaukee, WI, USA). Whole-body 18F-BPA PET/CT imaging was carried out at 1 h after the injection of 18F-BPA (ca. 4 MBq/kg). The scan timing for 18F-BPA PET/CT was determined as in our previous work [6 (link)]. Whole-body 11C-Met PET/CT was carried out 10 min after the injection of 11C-Met (ca. 4 MBq/kg). The scan timing for11C-Met PET/CT was determined by a previous report [15 (link)]. A scout image was first acquired to determine the scanning field range from the head to the pelvis of the patient, using settings of 10 mA and 120 kV. Next, whole-body 16-slice helical CT and whole-body 3D PET were performed. PET images were acquired in 7–8 bed positions with 2-min acquisition durations per bed position, such that the images covered the same field as the whole-body CT image. The acquired data were reconstructed as 192 × 192 matrix images (3.65 × 3.65 mm) using a 3D ordered subsets-expectation maximization algorithm.
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2

Multimodal Brain Imaging: MRI and PET

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Participants were scanned using a 3.0-T MRI scanner (Philips Achieva, Philips Medical Systems, Best, the Netherlands) with a SENSE head coil (SENSE factor=2). T1-weighted MRI data were obtained using a 3D T1-weighted turbo field echo sequence with the following parameters: axial acquisition matrix, 224×224; reconstructed matrix, 256×256 with 170 slices; voxel size, 0.859×0.859×1 mm3; field of view, 220 mm; echo time, 4.6 ms; repetition time, 9.8 ms; and flip angle, 8°.
FBB-PET and FC119S-PET data were acquired using a Discovery 600 scanner (General Electric Healthcare; Milwaukee, MI, USA). The FBB-PET images were acquired 90 min after FBB administration at 300 MBq (8 mCi) for 20 min. FC119S-PET images were acquired 30 min after FC119S administration at 370 MBq (10 mCi) for 30 min. PET images were acquired in a 256×256 matrix and were reconstructed using an ordered-subsets expectation-maximization algorithm in an isometric 0.98-mm voxel size.
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3

Dual-Time Point PET/CT Imaging of Ovarian and Breast Cancers

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Two patients were imaged with 2 different PET/CT scanners at Stanford. The ovarian cancer patient was imaged with a GE Discovery 600 scanner (14 minutes per scan), while the breast cancer patient was imaged with a GE Discovery MI scanner (18 minutes per scan). Participants were scanned with a low-dose attenuation correction CT scan (ACCT) followed by vertex to toes PET emission scan at 1hour (Scan #1) post-injection (p.i). After 24 hours p.i. patients received a second low-dose ACCT scan and a second vertex to toes PET emission scan (Scan #2). ACCT scan was performed with 120 kV and 10 mA. Whole body scans were analyzed using MIM Software (MIM, Cleveland, OH) and they were independently reviewed by 2 board certified nuclear medicine physicians.
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