Stealthviz software

Manufactured by Medtronic

Sourced in Ireland, Colombia

StealthViz is a software tool developed by Medtronic to provide advanced visualization and analysis capabilities for medical imaging data. It is designed to assist healthcare professionals in the interpretation and evaluation of medical images, such as those obtained from CT, MRI, or other imaging modalities.

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Lab products found in correlation

Framelink, by Medtronic (1 mentions) Nicolet cortical stimulator, by Natus (1 mentions) Stealthstation s8, by Medtronic (1 mentions)

Spelling variants of this product

StealthViz (5 citations) StealthViz (TM) Planning Station software (2 citations)

4 protocols using stealthviz software

Deep Brain Stimulation Targeting Methodology

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Pre-operatively, diffusion, T2, and T1-weighted post-gadolinium sequences were acquired on a 3-Tesla magnetic resonance imaging (MRI) system, as described previously^{1 (link)}.
Each patient’s MFB was individually mapped by means of deterministic fiber tracking using diffusion sequences. An area lateral to the VTA, anterior to the red nucleus, and posterior to the mammillary bodies was used as the seed region, as described by Coenen et al.^{27 (link)}. Using StealthViz software (Medtronic, Inc.), such mapping resulted in clear projections of the slMFB through to the medial prefrontal cortex. Results of such fiber tracking were then transferred to the stereotactic planning software (Framelink, Medtronic, Inc.), where the center of this fiber bundle superolateral to the VTA was used as the target for the DBS electrode, as previously described^{1 (link),2 (link)}.

Fenoy A.J., Schulz P.E., Selvaraj S., Burrows C.L., Zunta-Soares G., Durkin K., Zanotti-Fregonara P., Quevedo J, & Soares J.C. (2018). A longitudinal study on deep brain stimulation of the medial forebrain bundle for treatment-resistant depression. Translational Psychiatry, 8, 111.

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Diffusion Tensor Imaging Preprocessing

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Structural and diffusion weighted (60 directions of diffusion gradient) images were acquired on 3T MRI scanners. Eddy current and movement artifact corrections were applied. StealthViz software (v1, Medtronic Inc., Minneapolis, Minnesota) was used for tensor calculation. This software uses a deterministic tractography and is integrated with the stereotactic targeting software used for tremor surgery. The diffusion weighted and structural MRI images were coregistered, and the accuracy of coregistration was verified. Detailed methodology of the preprocessing pipeline is provided in the supplementary section.

Sammartino F., Krishna V., King N.K., Lozano A.M., Schwartz M.L., Huang Y, & Hodaie M. (2016). Tractography‐Based Ventral Intermediate Nucleus Targeting: Novel Methodology and Intraoperative Validation. Movement Disorders, 31(8), 1217-1225.

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Frontal Glioma Resection with FAT Identification

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After studying the anatomy of the FAT in 2015, the senior author (M.E.S.) began to perform all posterior frontal glioma resections with intra-operative neuronavigation, now including with the FAT as highlighted in the Medtronic Stealthviz Software (Medtronic, Dublin, Ireland). The identification of the FAT is demonstrated in Figure 1. Tumour location varied in relation to the FAT, but was often observed in front of the FAT (Figure 2). Regardless, we planned to resect these tumours by making coronal cuts parallel to the FAT so as to avoid resecting this tract.

Briggs R.G., Allan P.G., Poologaindran A., Dadario N.B., Young I.M., Ahsan S.A., Teo C, & Sughrue M.E. (2021). The Frontal Aslant Tract and Supplementary Motor Area Syndrome: Moving towards a Connectomic Initiation Axis. Cancers, 13(5), 1116.

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Intraoperative Electrocortical Stimulation Mapping

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Clinical presurgical tfMRI and DTI‐based tractography maps were formatted using StealthViz software (Medtronic Navigation, CO), merged with standard anatomic sequences (FLAIR, T₁‐precontrast and postcontrast) and imported onto neuronavigation system (Stealth Station S8, Medtronic Navigation, CO). Activation maps from clinical presurgical tfMRI were used to guide intraoperative stimulation. ECS was performed using a 60 Hz bipolar electrocortical stimulator (Nicolet Cortical Stimulator, Natus, WI) with biphasic pulses of 250 μs pulse width, and surgeon‐controlled train duration of 3 s. Stimulus intensity was generally kept between 2 and 12 mA, with motor threshold commonly lower than language threshold. Electrocorticography was performed using an 8‐contact strip electrode (Integra Lifesicences, NJ) for monitoring after discharges. Behavioral testing/monitoring was conducted by the same neuropsychologist who did preoperative testing. The coordinates of intraoperative ECS with a positive behavioral response were recorded in the Stealth workstation in reference to the FLAIR/T₁‐precontrast in LAS reference frame as image points. Motor function was not mapped with ECS in Patients 2 and 3 and language function was not mapped with ECS in Patient 5. Further detail is available in Supporting Information S1.

Vakamudi K., Posse S., Jung R., Cushnyr B, & Chohan M.O. (2019). Real‐time presurgical resting‐state fMRI in patients with brain tumors: Quality control and comparison with task‐fMRI and intraoperative mapping. Human Brain Mapping, 41(3), 797-814.

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