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Skyra 3.0t mri scanner

Manufactured by Siemens
Sourced in Germany

The SKYRA 3.0T MRI scanner is a magnetic resonance imaging system manufactured by Siemens. It operates at a magnetic field strength of 3.0 Tesla, which is commonly used for diagnostic imaging applications.

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12 protocols using skyra 3.0t mri scanner

1

Exploring Brain-Behavioral Phenotypes across Datasets

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We used data from n = 900 individuals from the HCP 1,200 Subject Data Release (aged 22–35 years). All HCP participants provided informed consent. A custom Siemens SKYRA 3.0T MRI scanner and a custom 32-channel head matrix coil were used to obtain high-resolution T1-weighted (MP-RAGE, TR = 2.4 s, 0.7 mm3 voxels) and BOLD contrast sensitive (gradient-echo EPI, multiband factor 8, TR = 0.72 s, 2 mm3 voxels) images from each participant. The HCP used sequences with left-to-right (LR) and right-to-left (RL) phase encoding, with a single RL and LR run on each day for two consecutive days for a total of four runs68 (link). MRI data were preprocessed as previously described62 (link). All HCP data are available at https://db.humanconnectome.org/.
Similar to the ABCD data, we extracted the timeseries from a total of 394 cortical and subcortical ROIs, correlated and Fisher z-transformed them. Data from the NIH Toolbox were correlated with each edge of the RSFC correlation matrix across participants. Across all NIH Toolbox subscales, the tails of the distributions of the resulting brain–behavioural phenotype correlations were compared to 100 subsampled ABCD brain–behavioural phenotype correlations (n = 877, matching HCP sample size). In Supplementary Fig. 8, we show the distributions of brain–behavioural phenotype correlations for ABCD and HCP data, for each NIH Toolbox subscale.
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2

Comprehensive Cardiac MRI Protocol for Tissue Characterization

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A Siemens SKYRA 3.0T MRI scanner was used, which was equipped with a phased array surface coil and electrocardiogram (ECG)-gating technology. The movies of the cross section and coronal plane of the black blood sequence and multi-sections of the true fast imaging with steady-state precession (true FISP) sequence (4-chamber view and 2-chamber view of the left ventricle, long axis view of the left ventricle passing through the outflow tract of the left ventricle, and continuous 9 to 12 layers of the short axis view from the atrioventricular valve ring to the cardiac apex) were routinely acquired. All patients underwent a delayed enhanced sequence scan of the myocardium and multiple low-b-value DWI sequence scanning of the short axis of the heart. The b-values (a parameter of the diffusion sensitive gradient field) were 0, 20, 60, 100, 150, 200, and 600 second/mm2, respectively. The scanning parameters were as follows: frequency-coding field of view (FOV) was 306 mm, phase-coding FOV was 75%, repetition time (TR) was 2200 milliseconds, echo time (TE) was 67 milliseconds, the thickness of slice was 8 mm, the gap was 1.5 to 3.5 mm, and the NEX was 8.00. Local shimming and the ECG-gating system were used. Scanning while breath-holding was performed at the end of expiration.
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3

Brain Imaging in Supine Position

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All participants lay supine on the bed of a Siemens Skyra 3.0-T MRI scanner with a standard 32-channel head coil to collect the MRI data at the Shanxi Provincial People’s Hospital. T1-weighted anatomical data were acquired by covering the entire brain using the MPRAGE sequence (repetition time/echo time = 2,300/2.95 ms, FA = 9°, data matrix = 225 × 240, 160 slices, slice thickness = 1.2 mm). Functional image was obtained using an EPI sequence (repetition time/echo time = 2,500/3.0 ms, FA = 90°, field of view = 240 × 240 mm, data matrix = 64 × 64, slice thickness = 4 mm, and 32 slices, 212 volumes).
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4

Facial Nerve Morphology Assessment

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MRI examination is to observe the morphology of the facial nerve of the temporal bone and the transverse diameters of the facial nerve mastoid; second, the genu and tympanic segments will be considered as the outcome indicators. The measurements will be performed within day 4 after onset and day 10 after onset. The MRI examination (SIEMENS MAGNETOM Skyra 3.0T MRI Scanner using head matrix coils) protocol for this study sequence is as follows: T1 three-dimensional magnetization-prepared rapid gradient-echo imaging with the following parameters: 256 × 256 mm field of view (FOV), repetition time/echo time (TR/TE) of 2000.00/1.97 ms, 192 sections of 1.0 mm thickness, with a voxel size = 1.0 × 1.0 × 1.0 mm, flip angle 20°, and acquisition time of 4 min, 40 s.
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5

3T MRI Acquisition Protocol for Functional Neuroimaging

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All MRI data were acquired on a Siemens Skyra 3.0 T MRI scanner before surgery. The complete MRI acquisition protocol included three-dimensional (3D) anatomical T1-weighted imaging and fMRI echo-planar imaging. The 3D anatomical T1-weighted imaging parameters were as follows: 176 sagittal slices, repetition time = 1900 ms, echo time = 3.57 ms, voxel size = 1 × 1 × 1 mm, and flip angle = 9°. The echo-planar imaging sequence parameters were as follows: 33 axial slices, slices thickness = 4 mm with a 0-mm gap, repetition time = 3000 ms, echo time = 30 ms, voxel size = 3.4 × 3.4 × 4 mm, and flip angle = 90°. During the fMRI imaging, 120 volumes were obtained that lasted 8.5 min.
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6

Comparing Brain-Behavior Relationships in HCP and ABCD Datasets

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We used data from n = 900 individuals from the HCP 1,200 Subject Data Release (aged 22–35 years). All HCP participants provided informed consent. A custom Siemens SKYRA 3.0T MRI scanner and a custom 32-channel head matrix coil were used to obtain high-resolution T1-weighted (MP-RAGE, TR = 2.4 s, 0.7 mm3 voxels) and BOLD contrast sensitive (gradient-echo EPI, multiband factor 8, TR = 0.72 s, 2 mm3 voxels) images from each participant. The HCP used sequences with left-to-right (LR) and right-to-left (RL) phase encoding, with a single RL and LR run on each day for two consecutive days for a total of four runs68 (link). MRI data were preprocessed as previously described62 (link). All HCP data are available at https://db.humanconnectome.org/.
Similar to the ABCD data, we extracted the timeseries from a total of 394 cortical and subcortical ROIs, correlated and Fisher z-transformed them. Data from the NIH Toolbox were correlated with each edge of the RSFC correlation matrix across participants. Across all NIH Toolbox subscales, the tails of the distributions of the resulting brain–behavioural phenotype correlations were compared to 100 subsampled ABCD brain–behavioural phenotype correlations (n = 877, matching HCP sample size). In Supplementary Fig. 8, we show the distributions of brain–behavioural phenotype correlations for ABCD and HCP data, for each NIH Toolbox subscale.
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7

High-resolution MRI for Human Connectome

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A custom Siemens SKYRA 3.0T MRI scanner and a custom 32 channel Head Matrix Coil were used to obtain high-resolution T1-weighted (MP-RAGE, 2.4s TR, 0.7×0.7×0.7mm voxels) and BOLD contrast sensitive (gradient echo EPI, multiband factor 8, 0.72s TR, 2×2×2mm voxels) images from each subject. The HCP used sequences with left-to-right and right-to-left phase encoding, with a single RL and LR run on each day for two consecutive days for a total of four runs (Van Essen et al., 2012 (link)). Thus, for symmetry, the BOLD time series from each subject’s best (most frames retained after censoring) LR run and their best RL run were concatenated together.
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8

Brain Imaging with Siemens Skyra 3T MRI

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All volunteers were scanned with a Siemens Skyra 3.0 T MRI scanner (Siemens Healthineers, Erlangen, Germany) using a 32-channel high-resolution phased array coil in the Nansha Imaging Center of Guangzhou First People’s Hospital. None of the participants were taking any medication that might have influenced cognition during the scans at the time of the study. The volunteers laid in a supine position with their heads fixed snugly with foam pads to minimize head motion. MRI sequences included 3D T1-weighted imaging and 3D SWI. An axial orientation parallel to the anterior commissure to the posterior commissure (AC-PC) line in all sequences covered the entire brain. T1-weighted imaging was performed under the following parameters: repetition time (TR) =2,530 ms, echo time (TE) =2.96 ms, slice thickness =1.0 mm, flip angle =7°, field of view =256×256 mm2, and acquisition matrix =352×352. SWI was performed with the following parameters: TR =28 ms, TE =20 ms, slice thickness =1.0 mm, flip angle =15°, field of view (FOV) =220×193.8 mm2, and acquisition matrix =352×352.
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9

High-Resolution 3D T1-Weighted MRI Acquisition

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MRI scans were performed using a Magnetom Skyra 3.0T MRI scanner (Siemens, Germany) with a 32channel phased-array head coil. All participants underwent 3D-T1WI scanning with the following scan parameters: magnetization-prepared rapid gradient-echo (MP-RAGE) sequence with a repetition time (TR) = 2,000 ms, inversion time (TI) = 880 ms, echo time (TE) = 2.01 ms, ip angle (FA) = 8°, matrix = 256 × 256, eld of view (FOV) = 256 × 256 m 2 , total sagittal thickness = 208 mm, and thickness = 1 mm.
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10

Multimodal MRI Scanning Protocol for Surgical Patients

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Participants underwent structural and functional MRI scanning before surgeries. MRI data were collected using a Skyra 3.0T MRI scanner (Siemens, Erlangen, Germany) equipped with a 32‐channel head coil at the FAH‐FMU. High‐resolution T1‐weighted (T1w) anatomical images were acquired using an MPRAGE 3D T1w sequence (TR = 2300 ms, TE = 3.09 ms, flip angle = 9°, FOV = 256 × 256, 256 × 256 matrix, 192 sagittal slices, and voxel size = 1 × 1 × 1 mm3). Additionally, high‐resolution T2w images were acquired using the 3D T2w fluid‐attenuated inversion recovery sequence (TR = 5000 ms, TE = 387 ms, FOV = 230 × 230, 230 × 230 matrix, 192 sagittal slices, and voxel size = 1 × 1 × 0.9 mm3). Rs‐fMRI was acquired with an echo planar imaging (EPI) pulse sequence (TR = 3000 ms, TE = 30 ms, flip angle = 90°, FOV = 240 × 240, 80 × 80 matrix, 50 slices, voxel size = 3 × 3 × 3.4 mm3). Participants were required to keep their bodies and heads still, eyes closed, and not to fall asleep during the entire scanning. To ensure a sufficient data amount of rs‐fMRI for reliable personalized functional mapping, each rs‐fMRI session included three repeated runs (29 min 33 s in total) for each participant. All patients underwent a post‐operative MRI session a week after surgeries. The session included T1w and T2w FLAIR scans to identify lesion locations.
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