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Anti mouse cd25 pc 61.5.3

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The Anti-mouse CD25 (PC-61.5.3) is a monoclonal antibody that binds to the CD25 antigen expressed on activated T cells and regulatory T cells in mice. It is commonly used in research applications to study the role of CD25-positive cells in immune responses and regulatory processes.

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Lab products found in correlation

Irdye 700dx nhs ester, by LI COR (1 mentions)

2 protocols using anti mouse cd25 pc 61.5.3

1

CD44 and CD25 Antibody Labeling

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Water soluble, silica-phthalocyanine derivative, IRDye700DX NHS ester was obtained from LI-COR Bioscience (Lincoln, NE, USA). An anti-mouse/human CD44 (IM7) and anti-mouse CD25 (PC-61.5.3) were purchased from Bio X Cell. All other chemicals were of reagent grade.
Maruoka Y., Furusawa A., Okada R., Inagaki F., Fujimura D., Wakiyama H., Kato T., Nagaya T., Choyke P.L, & Kobayashi H. (2020). Combined CD44- and CD25-targeted Near-Infrared Photoimmunotherapy Selectively Kills Cancer and Regulatory T cells in Syngeneic Mouse Cancer Models. Cancer immunology research, 8(3), 345-355.
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2

Murine Anti-CD20 and BAFFR-Fc Treatments

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Murine anti-CD20 IgG2c mAb (MB20.11) administered intraperitoneally at 250 μg doses at 2-week intervals, has been described (9 (link)) and was provided by MedImmune. BAFFR-Fc, a fusion protein with the extracellular portion of BAFFR fused to the Fc domain of mouse IgG1, was dosed at 200 μg intraperitoneally twice a week and was also obtained from MedImmune (34 ). An irrelevant control murine IgG1 antibody (ctrl mAb) supplied by MedImmune was dosed at 200 μg intraperitoneally twice a week. Anti-mouse IL-10 (JES5-2A5, BioXcell) was initially dosed at 500 μg intraperitoneally twice a week for 2 weeks followed by a maintenance dose of 200 μg twice a week. Anti-mouse CD25 (PC-61.5.3, BioXcell) administered intraperitoneally at 250 μg doses at 2-week intervals has been described (8 (link)).
Wang Q., Racine J.J., Ratiu J.J., Wang S., Ettinger R., Wasserfall C., Atkinson M.A, & Serreze D.V. (2017). Transient BAFF blockade inhibits type 1 diabetes development in NOD mice by enriching immunoregulatory B-lymphocytes sensitive to deletion by anti-CD20 co-therapy,. Journal of immunology (Baltimore, Md. : 1950), 199(11), 3757-3770.
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