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Stata version 14.2 for windows

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Stata version 14.2 for Windows is a statistical software package developed by StataCorp. It provides a comprehensive set of tools for data analysis, management, and visualization. The software supports a wide range of statistical techniques, including regression analysis, time series analysis, and survey data analysis.

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10 protocols using stata version 14.2 for windows

1

Cardiac Structure and Function in HIV

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Continuous variables are described as medians (interquartile range [IQR]) and compared using the Wilcoxon rank‐sum test. Categorical variables are presented as an absolute value (percentage) and compared using χ2 statistics. Multivariable linear regression analyses were used to investigate the associations between HIV serostatus and cardiac structure and function, adjusting for the following:

Model 1: Age, race, body mass index (for echocardiographic metrics not normalized to body surface area), educational level, MACS site, and wave of MACS enrollment (before/after 2001);

Model 2: Model 1+further adjustment for heart rate, systolic blood pressure, antihypertensive medications, diabetes mellitus, dyslipidemia, smoking status, alcohol intake, history of cardiovascular disease, and history of cocaine consumption.

Using the same models above, we also performed an exploratory analysis among participants who were HIV+ to assess the association between the echocardiographic metrics and HIV disease severity factors and treatments.
A sensitivity analysis was also performed by excluding men with prior cardiovascular disease history. All statistical analyses were conducted using Stata 14.2 version for Windows (StataCorp LP, College Station, TX). A 2‐tailed P value of <0.05 was considered statistically significant.
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2

Cardiac Structure and Function in Obesity

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Continuous variables are presented as means ± SD or as medians and interquartile ranges and compared using Student’s t test or Wilcoxon rank-sum test (Mann-Whitney) as appropriate. Categorical variables are presented as absolute values (percentage) and compared using χ2 statistics. Multivariable linear regression analyses were used to assess the relationship between cBMI with 3D echocardiography LA structure/function parameters, assessed by two analytic models: model 1 was adjusted for demographics at year 30 examination (age and race); model 2 included model 1 with adjustment for traditional CV risk factors at year 30 examination (heart rate, education level, physical activity, systolic blood pressure, smoking status, diabetes, alcohol intake, LDL cholesterol, and HDL cholesterol). Effect modification by sex on the association of cBMI with several LA parameters was observed; therefore, all assessments were stratified by sex. All analyses were conducted using STATA 14.2 version for Windows (StataCorp LP, College Station, TX). A two-tail P value < .05 was considered statistically significant.
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3

Cardiac Structure and Function in Obesity

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Continuous variables are presented as means ± SD or as medians and interquartile ranges and compared using Student’s t test or Wilcoxon rank-sum test (Mann-Whitney) as appropriate. Categorical variables are presented as absolute values (percentage) and compared using χ2 statistics. Multivariable linear regression analyses were used to assess the relationship between cBMI with 3D echocardiography LA structure/function parameters, assessed by two analytic models: model 1 was adjusted for demographics at year 30 examination (age and race); model 2 included model 1 with adjustment for traditional CV risk factors at year 30 examination (heart rate, education level, physical activity, systolic blood pressure, smoking status, diabetes, alcohol intake, LDL cholesterol, and HDL cholesterol). Effect modification by sex on the association of cBMI with several LA parameters was observed; therefore, all assessments were stratified by sex. All analyses were conducted using STATA 14.2 version for Windows (StataCorp LP, College Station, TX). A two-tail P value < .05 was considered statistically significant.
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4

Demographic Factors and CV Risk Indices

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Continuous variables are present as mean ± SD and compared using Student t-test. Categorical variables are present as absolute values (percentage) and compared using chi-square statistics. Specific Age, gender, and race/ethnicity categories reference values were obtained for the entire study group, NRF, and RF groups. Also, multivariate linear regression models adjusted for demographic characteristics were performed to evaluate differences in LA indices by age, gender, and race/ethnicity and CV risk factors components. All analyses were conducted using STATA 14.2 version for Windows (StataCorp LP, College Station, TX). All tests were two-tailed and considered statistically significant when p-value ≤ 0.05.
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5

Predictors of Early Discharge Post-SCI

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Analyses were conducted using Stata version 14.2 for Windows (College Station, TX, USA). Descriptive statistics were used to describe the population of potentially eligible patients and the simulation results. Continuous variables were tested for normality. Chi-square, Fisher’s exact, and Kruskal-Wallis tests were used to test for differences across study years and models of LEMS cut-offs. Imbalance in the randomization lists was investigated and reported as the absolute difference between the proportion of participants assigned to either intervention [23 (link)]. To describe participant flow, the intervention start was defined as day 34 (middle of the baseline assessment window) and intervention end as day 91 (middle of three-month follow-up window). Multivariable logistic regression was used to identify predictors of early discharge from the hospital within the TASCI intervention time period (< 81 days after SCI diagnosis).
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6

Factors Associated with Treatment Adherence

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Univariate analysis was performed with Chi-square or Fisher’s exact test. Multivariate logistic regression was performed for variables with p<0.25 based on univariate analysis. Stata version 14.2 for Windows was adopted for statistical analysis. Two-tailed p≤0.05 was considered as statistically significant. Variables that had missing data were excluded from multivariate analysis. Patients who moved to another health facility and treated irregularly were excluded from the study.
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7

Predictors of Early Discharge Post-SCI

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Analyses were conducted using Stata version 14.2 for Windows (College Station, TX, USA). Descriptive statistics were used to describe the population of potentially eligible patients and the simulation results. Continuous variables were tested for normality. Chi-square, Fisher’s exact, and Kruskal-Wallis tests were used to test for differences across study years and models of LEMS cut-offs. Imbalance in the randomization lists was investigated and reported as the absolute difference between the proportion of participants assigned to either intervention [23 (link)]. To describe participant flow, the intervention start was defined as day 34 (middle of the baseline assessment window) and intervention end as day 91 (middle of three-month follow-up window). Multivariable logistic regression was used to identify predictors of early discharge from the hospital within the TASCI intervention time period (< 81 days after SCI diagnosis).
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8

Statistical Analysis of Quantitative Data

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Data in this study were quantitatively analysed with descriptive statistics using STATA version 14.2 for Windows (StataCorp, 2015). All data gathered were summarised by indicating the distribution of data and measure of variability. Data normally distributed were expressed as mean ± standard deviation (SD), whilst those not normally distributed were described as median and frequency (n, %).
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9

Dietary Guidelines Compliance Trends

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Statistical analyses were conducted using Stata version 14.2 for windows (Stata Corp, College Station, Texas, USA). Participants characteristics were expressed as number (percentage) for categorical variables or as average ± standard deviation for continuous variables. Prevalence rates for compliance for the first (2009-2012) and the second (2014-2017) follow-up were presented as rates (95% confidence interval) using the exact Poisson method. Paired analyses were conducted using the participant as her/his control using the McNemar test for paired proportions. The factors associated with changes in compliance were assessed by multivariable analysis using multinomial logistic regression and the "Never compliers" as reference. A sensitivity analysis was conducted by assessing the prevalence and determinants of an improvement in the number of dietary guidelines complied to. Statistical significance was assessed for a two-sided test with p<0.05.
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10

Dietary Patterns and Heart Failure Risk

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Descriptive statistics were utilized to summarize participant characteristics according to DASH score categories. Data are presented as mean ± SD for continuous variables and number (percentage) for categorical variables. Differences in baseline participant characteristics by quintile of DASH score were tested with Student’s t-test (continuous variables with normal distribution) or chi-square test (categorical variables). Log rank tests were used to compare the incidence of HF by DASH score quintile. Subsequently, Cox proportional hazards models were used to analyze the association of dietary pattern with incident HF. For all regression models, adjustment was made for demographic factors (age, sex, study site, educational level, and race/ethnicity), traditional CVD risk factors (systolic BP and diastolic BP, use of antihypertensive medications, lipids, diabetes mellitus, smoking, alcohol intake, and exercise), BMI, and eGFR. Four sets of models were used: Model 1: gender and age; Model 2: plus race, education, energy, cigarette use, site, exercise, energy and BMI; Model 3 adjusted for Model 2 adjusted for HTN, diabetes, high-density lipoprotein (known disease associations with HF); and Model 4 adjusted for Model 3 plus EF, LV mass (pathophysiology of HF). Analyses were performed using Stata, version 14.2 for Windows.
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