Quercetin (CAS NO: 117-39-5, purity > 95%, Figure 1A ) was purchased from Sigma-Aldrich. Kits for detecting SOD and MDA were purchased from Nanjing Jiancheng Bioengineering Institute. The antibodies for PSD93, PSD95, SIRT1, Caspase3, Bax, Bcl2, PERK, P-PERK, eIF2α, P-eIF2α, IRE-1α, P-IRE-1α, BIP, PDI were provided by Cell Signaling Technology (MA, USA). Anti-β-actin, BDNF, NGF, ATF6 were purchased from Abcam, Inc (Cambridge, England).
Quercetin cas no 117 39 5
Manufactured by Merck Group
Sourced in United States
Quercetin (CAS NO: 117-39-5) is a naturally occurring flavonoid compound. It is commonly used as a reference standard and in research applications.
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Lab products found in correlation
Nerve growth factor (ngf), by Abcam (1 mentions)
P ire1α, by Cell Signaling Technology (1 mentions)
Eif2α, by Cell Signaling Technology (1 mentions)
Brain derived neurotrophic factor (bdnf), by Abcam (1 mentions)
Caspase 3, by Cell Signaling Technology (1 mentions)
Sirt1, by Cell Signaling Technology (1 mentions)
P perk, by Cell Signaling Technology (1 mentions)
Psd93, by Cell Signaling Technology (1 mentions)
Ire1α, by Cell Signaling Technology (1 mentions)
P eif2α, by Cell Signaling Technology (1 mentions)
Bcl2 associated x (bax), by Cell Signaling Technology (1 mentions)
Bcl 2, by Cell Signaling Technology (1 mentions)
P erk, by Cell Signaling Technology (1 mentions)
Anti β actin, by Abcam (1 mentions)
2 protocols using quercetin cas no 117 39 5
1
Quercetin Neuroprotective Mechanism Evaluation
2
Xiaoyao Pill and Fluoxetine in Mice
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The Xiaoyao pill, which was obtained from Guangdong Provincial Hospital of Chinese Medicine, was dissolved in normal saline to yield a suspension. According to the conversion coefficient between adult and mice, the dosage of the Xiaoyao pill for mice was 6.1 g/kg. The mice were treated with Xiaoyao pill by intragastric administration once a day. Fluoxetine hydrochloride was purchased from Guangdong Provincial Hospital of Chinese Medicine and dissolved in normal saline to yield a suspension. The mice received fluoxetine via intragastric administration at a dose of 1.8 mg/kg once a day. Quercetin (CAS No. 117-39-5, purity ≥95%) was obtained from Sigma-Aldrich (St. Louis, MO, USA). Stock solutions of 100 mM concentration were prepared in dimethyl sulfoxide (DMSO) and stored at –20 °C. Quercetin was diluted as needed in the experimental medium.
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