Cardiac magnetic resonance scans were performed on a study‐dedicated 1.5‐T Signa Twinspeed system (GE Healthcare) using a 4‐element cardiac‐phased array coil. Typical cine steady‐state free precession scan parameters resulted in pixel dimensions of 1.8×2.1 mm, a slice thickness of 8 mm with a 3‐mm gap, and 30 images per cycle. Standard long‐axis and short‐axis views were obtained to evaluate global and regional function. End‐systolic phase was determined as the minimal cross‐sectional area of a midventricular slice. Left ventricular end diastolic volume (LVEDV) and left ventricular end systolic volume (LVESV) were computed by the summation of disks method. Left ventricular stroke volume (LVSV) in mL was calculated by subtracting LVESV from LVEDV. Left ventricular ejection fraction (LVEF) in % was calculated as LVSV/LVED×100 and cardiac output (CO) in L/min was calculated as LVSV/1000× heartbeat per minute.
Signa twinspeed
Manufactured by GE Healthcare
Sourced in United States, United Kingdom
The Signa Twinspeed is a magnetic resonance imaging (MRI) system developed by GE Healthcare. It is designed to provide high-quality imaging for a wide range of clinical applications. The system features a powerful superconducting magnet and advanced radiofrequency and gradient subsystems to enable fast and efficient data acquisition.
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13 protocols using signa twinspeed
1
Cardiac MRI Quantification Protocol
2
Cardiac MRI Assessment of Chemotherapy Effects
3
Evaluation of Sacroiliac Joint MRI in Pediatrics
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MRI examinations were performed at either 1.5 Tesla with a Signa Twinspeed or 3 Tesla Discovery 750HD scanner (General Electric Medical Systems, Milwaukee, WI) with patients placed in supine position. The following pulse sequences were obtained in an oblique coronal orientation dedicated to the SI joints: short tau inversion recovery (STIR), T1-weighted, and T1-weighted fat saturated pre- and post-gadolinium (intravenous Gd-DTPA 0.1 mmol/kg body weight) contrast enhanced images. The slice thickness was 4-5 mm; field of view = 20 cm; matrix = 512 × 512 for the T1-weighted sequence and 256 × 256 for the STIR and fat saturated T1-weighted sequences.
MR images were evaluated by a board-certified pediatric radiologist with an extra-year of fellowship training in musculoskeletal radiology and six years of post-fellowship experience. A subset of 22 MRI exams were evaluated independently by another board-certified pediatric radiologist with an additional year of fellowship training in abdominal and pelvic imaging and three years of post-fellowship experience in the interpretation of imaging examinations of pediatric bones and joints.
MR images were evaluated by a board-certified pediatric radiologist with an extra-year of fellowship training in musculoskeletal radiology and six years of post-fellowship experience. A subset of 22 MRI exams were evaluated independently by another board-certified pediatric radiologist with an additional year of fellowship training in abdominal and pelvic imaging and three years of post-fellowship experience in the interpretation of imaging examinations of pediatric bones and joints.
4
Brain MRI Metrics and Cerebrovascular Outcomes
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MR images were collected using 1.5T brain MRI (Signa TwinSpeed; General Electric Medical Systems). For more information on the MRI protocol, refer to [26 (link)–28 (link)]. Log-transformed white matter lesion volume and hippocampal volume, as well as the ratio of gray matter/intracranial volume (to account for correlation), and the number of cerebral microbleeds were entered as continuous predictors. The presence of infarcts (yes/no) was entered as a dichotomous variable.
5
MRI Acquisition Protocol for Brain Imaging
6
Breast MRI Protocol for Cancer Diagnosis
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MR imaging was performed on a 1.5 T MRI system (Signa Twinspeed; GE Medical Systems, USA) with an eight-channel phased-array bilateral breast coil. The MRI protocol included axial T1-weighted imaging T2-weighted imaging, diffusion-weighted imaging, and DCE-MRI. Three-dimensional axial T1WI volume sequence of DCE MR imaging was performed every 58 s to scan 124 slices (TR 6 ms/TE 2.6 ms; FOV, 32 cm × 32 cm; matrix, 384 × 288; slice thickness, 2.4 mm; intersection gap, 0 mm; bandwidth, 62.5 Hz; and NEX,1). The DCE-MRI acquisitions were started after intravenous administration of 0.1 mmol/kg of Gd-DTPA (Magnevist, Bayer Schering Pharma, Germany), followed by a flush of 20 ml of saline solution with the flow of about 2 ml/s. The acquisition was repeated eight times, and each phase took 58 seconds.
7
MRI Protocol for Acute Optic Neuritis
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Magnetic resonance imaging (MRI) of the brain and orbits were reviewed retrospectively. The MRI examinations were performed on two different scanners, a 3.0T scanner (Ingenia; Philips Healthcare, Best, the Netherlands) and a 1.5T scanner (Signa TwinSpeed; GE Healthcare), using our standard brain and orbit MRI protocols that included axial and coronal contrast-enhanced T1-weighted images with fat suppression (CE-T1W/FS), T2-weighted images with fat suppression and axial fluid-attenuation inversion recovery images (FLAIR). Enhancement of the optic nerve on CE-T1W/FS is highly sensitive for acute ON detection.
8
Liver MRI Contrast Protocol
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All patients underwent MRI using a 3.0-T scanner (Discovery MR750; GE Healthcare, or SIGNA HDx, Little Chalfont, UK) or a 1.5-T scanner (Signa Twinspeed; GE Healthcare) with an eight-channel phased-array software coil covering the entire liver. The MRI scan sequences from both institutions are shown in Supplemental Table 1. Gadodiamide (OMNISCAN, 15 mL 4.305 g) was injected intravenously for image acquisition. Scans were conducted at 20, 60, and 180 seconds after injection to obtain arterial, portal venous, and delayed phase images (AP, PP, and DP).
9
MRI Segmentation and Lesion Analysis Protocol
10
Orbital MRI and Ultrasonography Protocol
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Orbital MRI scans were performed using a 1.5 T MRI scanner (Signa TwinSpeed; GE Healthcare, Milwaukee, WI) with dual 7.6-mm surface coils. Spin echo T1-weighted image was carried out at a time of repetition (TR) of 600.0 ms and a time of echo (TE) of 11.1 ms. The fast spin echo T2-weighted image acquisition parameters were at TR 3000 ms and TE 120 ms. Gadopentetate dimeglumine (0.1 mmol/kg, Magnevist; Bayer Schering Pharma, Berlin, Germany) was injected and dynamic contrast-enhanced MRI were obtained employing 3D-fast spoiled gradient echo (TR 8.4 ms, TE 4.0 ms, flip angle 15°, field of view 220 × 220 mm, matrix size 256 × 160, slice thickness 3.2 mm with 0 spacing and 5 minutes acquisition time).
B-mode ultrasonography and CDFI were performed using Mylab 90× vision diagnostic instruments (Esaote, Shenzhen, China). B-type ultrasonography was used to identify the location and measure the base diameter and height of the tumor. The CM volume was calculated by the equation: V = 2лa2b/3, where V = tumor volume, a = base diameter/2, and b = height.[25 (link)] CDFI was used to observe tumor blood flow with a frequency range of 6 to 18 MHz.
B-mode ultrasonography and CDFI were performed using Mylab 90× vision diagnostic instruments (Esaote, Shenzhen, China). B-type ultrasonography was used to identify the location and measure the base diameter and height of the tumor. The CM volume was calculated by the equation: V = 2лa2b/3, where V = tumor volume, a = base diameter/2, and b = height.[25 (link)] CDFI was used to observe tumor blood flow with a frequency range of 6 to 18 MHz.
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