Rapamycin

Manufactured by Chemietek

Rapamycin is a macrocyclic lactone compound produced by the bacterium Streptomyces hygroscopicus. It functions as an immunosuppressant and has been used in the prevention of organ transplant rejection.

Automatically generated - may contain errors

Lab products found in correlation

Erlotinib, by Chemietek (1 mentions) Sunitinib, by Chemietek (1 mentions) Everolimus, by Chemietek (1 mentions) Abt 199, by Chemietek (1 mentions) Gemcitabine, by Chemietek (1 mentions) Mitomycin c, by MedKoo Biosciences (1 mentions) Abt 263, by Chemietek (1 mentions)

2 protocols using rapamycin

Glucose Deprivation and 2-DG Treatment

Check if the same lab product or an alternative is used in the 5 most similar protocols

Analysis was performed as previously described [50 (link)]. The cells were incubated in culture medium deprived of glucose (Sigma). 2-DG (Sigma) in PBS was diluted to the required concentrations with culture medium. Cells were further treated with pre-optimized 0.5 mM glucose or 20 mM 2-DG at the indicated days. Rapamycin (Chemietek) in DMSO was diluted to the indicated concentrations with culture media, SRB staining was performed to evaluate the cell growth after 72 h.

Wang Y., Yu T., Zhou Y., Wang S., Zhou X., Wang L., Ou T., Chen Y., Zhou Y., Zhang H., Wang Y., Fan X., Chen P., Gonzalez F.J., Yu A., Huang P., Huang M, & Bi H. (2020). Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence. Aging (Albany NY), 12(8), 6733-6755.

+ Open protocol

+ Expand

Compound Sources for CIVO and Systemic Studies

Check if the same lab product or an alternative is used in the 5 most similar protocols

Compounds used in the CIVO and systemic studies were purchased from Selleck Chemicals (Everolimus, Sunitinib, 5-Fluorouracil, Rapamycin, Gemcitabine, ABT-199, ABT-263, Erlotinib), Chemietek (ABT-263, ABT-199) and Medkoo Biosciences (Mitomycin C). Abraxane^® was manufactured by Celgene Corporation (San Diego, CA).

Dey J., Kerwin W.S., Grenley M.O., Casalini J.R., Tretyak I., Ditzler S.H., Thirstrup D.J., Frazier J.P., Pierce D.W., Carleton M, & Klinghoffer R.A. (2016). A Platform for Rapid, Quantitative Assessment of Multiple Drug Combinations Simultaneously in Solid Tumors In Vivo. PLoS ONE, 11(6), e0158617.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!