Telmisartan

Manufactured by LGC

Sourced in United States

Telmisartan is a pharmaceutical ingredient used in the manufacture of various lab equipment. It is a white to slightly yellowish crystalline powder. Telmisartan is primarily used as an active pharmaceutical ingredient in the production of medical devices and laboratory equipment.

Automatically generated - may contain errors

Lab products found in correlation

4 hydroxydiclofenac, by LGC (2 mentions) Bac to bac baculovirus expression system, by Thermo Fisher Scientific (2 mentions) Mouse monoclonal anti or antibody, by Santa Cruz Biotechnology (2 mentions) 4 hydroxytolbutamide, by LGC (2 mentions) Losartan, by Merck Group (1 mentions) Tolbutamide, by Merck Group (1 mentions) Cellfectin transfection reagent, by Thermo Fisher Scientific (1 mentions) Restriction enzyme, by Takara Bio (1 mentions) High performance liquid chromatography grade solvents, by Thermo Fisher Scientific (1 mentions) Sf 900 3 sfm insect culture medium, by Thermo Fisher Scientific (1 mentions) Diclofenac, by Tokyo Chemical Industry (1 mentions) Nadph regenerating system, by Promega (1 mentions) Supersignal west pico trial kit, by Thermo Fisher Scientific (1 mentions) Primestar hs dna polymerase and restriction enzymes, by Takara Bio (1 mentions) High pressure liquid chromatography grade solvents, by Thermo Fisher Scientific (1 mentions) Tianamp blood dna midi kit, by Tiangen Biotech (1 mentions)

2 protocols using telmisartan

Recombinant Protein Production in Insect Cells

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Spodoptera frugiperda (Sf)21 insect cells, Sf‐900™ III SFM insect culture medium, Cellfectin transfection reagent, Grace's Insect Medium, fetal bovine serum, and the Bac‐to‐Bac Baculovirus Expression System were purchased from Invitrogen. Restriction enzymes were obtained from Takara Bio. Rabbit polyclonal anti‐CYP2C9 antibody was obtained from AbD Serotec. The mouse monoclonal anti‐OR antibody was from Santa Cruz Biotechnology. Diclofenac and chlorpropamide were obtained from Tokyo Chemical Industry Co., Ltd. Tolbutamide, losartan, and E‐3174 were purchased from Sigma‐Aldrich. 4‐hydroxyDiclofenac, 4‐hydroxyTolbutamide, and telmisartan were purchased from Toronto Research Chemicals Inc. High‐performance liquid chromatography‐grade solvents were purchased from Fisher Scientific Co. All the other chemicals and solvents were of the highest grade or analytical grade that were commercially available.

Liu J., Chen H., Wang S., Zhou Q., Geng P., Zhou Y., Wu H., Shi H., Wang F., Yang J., Cai J, & Dai D. (2021). Functional characterization of the defective CYP2C9 variant CYP2C9*18. Pharmacology Research & Perspectives, 9(1), e00718.

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Baculovirus-Mediated Recombinant Protein Expression

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Materials and kits were purchased from the following sources: TIANamp Blood DNA Midi Kit (TIANGEN, Beijing, China); PrimeSTAR HS DNA polymerase and restriction enzymes (Takara Bio, Inc.; Otsu, Shiga, Japan); Spodoptera frugiperda (Sf)21 insect cells, Sf-900TM III SFM insect culture medium and Bac to-Bac Baculovirus Expression System (Invitrogen, Carlsbad, CA, United States); Mouse monoclonal anti-OR antibody (Santa Cruz Biotechnology, Dallas, Texas, United States); Rabbit polyclonal anti-CYP2C9 antibody (Abcam, Cambridge, United Kingdom); Super Signal West Pico Trial Kit (Thermo Scientific, Rockford, IL, United States); 4-Hydroxytolbutamide, 4-hydroxydiclofenac, and telmisartan (Toronto Research Chemicals, Inc.; Toronto, Ontario, Canada); Diclofenac and chlorpropamide (Tokyo Chemical Industry Co., Ltd.; Tokyo, Japan); Tolbutamide, losartan and E-3174 (Sigma-Aldrich, St. Louis, MO, United States); NADPH-regenerating system (Promega, Madison, WI, United States); High-pressure liquid chromatography-grade solvents (Fisher Scientific Co.; Fair Lawn, NJ, United States). All other chemicals and reagents were of analytical grade or the highest commercially available quality.

Zhao F.L., Zhang Q., Wang S.H., Hong Y., Zhou S., Zhou Q., Geng P.W., Luo Q.F., Yang J.F., Chen H., Cai J.P, & Dai D.P. (2022). Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C9*72-*75 in the Chinese Han population. Frontiers in Pharmacology, 13, 1007268.

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