D2 wt

Manufactured by Jackson ImmunoResearch

D2 WT is a laboratory instrument produced by Jackson ImmunoResearch. It is used for the analysis and detection of biological samples.

Automatically generated - may contain errors

Lab products found in correlation

D2 mdx, by Jackson ImmunoResearch (3 mentions) C57 mdx, by Jackson ImmunoResearch (3 mentions) C57 wt, by Jackson ImmunoResearch (3 mentions)

3 protocols using d2 wt

Mdx Mouse Tissue Collection

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Male C57 mdx (n = 12), C57 WT (n = 12), D2 mdx (n = 12), and D2 WT (n = 12) mice were purchased from Jackson Laboratories at 7–8 weeks of age. They were acclimated and housed in Brock University’s Animal Facility, in an environmentally controlled room with a standard 12:12 h light-dark cycle and allowed access to food and water ad libitum. After the mice reached 9–10 weeks of age, they were euthanized via cervical dislocation under general anesthetic (vaporized isoflurane) and their tissues were collected.

Cleverdon R.E., Braun J.L., Geromella M.S., Whitley K.C., Marko D.M., Hamstra S.I., Roy B.D., MacPherson R.E, & Fajardo V.A. (2022). Sarco(endo)plasmic reticulum Ca2+-ATPase function is impaired in skeletal and cardiac muscles from young DBA/2J mdx mice. iScience, 25(9), 104972.

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Muscular Dystrophy Mouse Model Characterization

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Male C57 mdx, C57 WT, D2 mdx, and D2 WT mice (n = 6 group) were purchased at 6-7 weeks of age from Jackson Laboratories. The mice were acclimated and housed in Brock University's Animal Facility, in an environmentally controlled room with a standard 12:12 hour light-dark cycle. The mice were allowed access to food and water ad libitum. After the mice reached 8-10 weeks of age, they were euthanized via exsanguination under general anesthetic (vaporized isoflurane) and their muscles and serum were collected. All animal procedures were reviewed and approved by the Animal Care Committee of Brock University and followed the guidelines of the Canadian Council on Animal Care (AUP 17-06-03).

Copeland E.N., Watson C.J.F., Whitley K.C., Baranowski B.J., Kurgan N., MacNeil A.J., MacPherson R.E.K., Fajardo V.A, & Allison D.J. (2022). Kynurenine metabolism is altered in mdx mice: a potential muscle to brain connection. Experimental physiology, 107(9).

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Murine Dystrophy Model Protocols

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All mice, C57 mdx (stock #013141), D2-mdx (stock #001801), C57 WT (stock number 000476) and D2 WT (stock #000671), were ordered from Jackson Laboratories. Upon arrival, they were acclimated and housed in Brock University's Animal Facility, in an environmentally controlled room with a standard 12:12 hour light-dark cycle and allowed access to food and water ad libitum. All animal procedures were approved by the Brock University Animal Care and Utilization Committee (file #17-06-03) and were carried out in accordance with the Canadian Council on Animal Care guidelines.

Marcella B., Hockey B., Braun J.L., Whitley K.C., Geromella M.S., Baranowski R.W., Watson C.J.F., Silvera S., Hamstra S.I., Wasilewicz L.J., Crozier R.W.E., Marais A., Vandenboom R., Roy B.D., MacNeil A.J., MacPherson R.E.K., & Fajardo V.A. (2022). GSK3 inhibition improves skeletal muscle function and whole-body metabolism in the severe DBA/2Jmdxmouse model.

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