Polyethylene glycol peg 400

Manufactured by HiMedia

Sourced in India

Polyethylene glycol (PEG) 400 is a clear, odorless, and viscous liquid. It is a type of polyether compound with a wide range of molecular weights. PEG 400 has a molecular weight range of 380 to 420 g/mol. It is commonly used as a solvent, emulsifier, and humectant in various industries, including pharmaceutical, cosmetic, and personal care products.

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Lab products found in correlation

Labrasol, by Gattefosse (2 mentions) Tween 80, by HiMedia (1 mentions) Acetonitrile, by Merck Group (1 mentions) Methanol, by Merck Group (1 mentions) Milli q water purification system, by Merck Group (1 mentions) Labrafac pg, by Gattefosse (1 mentions) Propylene glycol, by HiMedia (1 mentions) Transcutol p, by Gattefosse (1 mentions) Capryol 90, by Gattefosse (1 mentions) Labrafil m, by Gattefosse (1 mentions)

2 protocols using polyethylene glycol peg 400

Excipient Characterization for Drug Delivery

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CR was purchased from Sigma Aldrich Co. (St Louis, MO, USA). Tween 80, and polyethylene glycol (PEG) 400 was procured from Hi-Media (Mumbai, India). Labrafac PG and Labrasol were generously gifted by Gattefosse, Bad Krozingen, Germany. Glyceryl triacetate (triacetin) was purchased from Thomas Baker, Mumbai, India. High performance liquid chromatography (HPLC) grade methanol and acetonitrile were purchased from Merck Millipore, India. MilliQ water produced in-house by MilliQ water purification system (EMD Millipore, Billerica, MA, USA) was used for all the experiments. All other chemicals and reagents were of analytical grade.

Naz Z, & Ahmad F.J. (2015). Curcumin-loaded colloidal carrier system: formulation optimization, mechanistic insight, ex vivo and in vivo evaluation. International Journal of Nanomedicine, 10, 4293-4307.

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Dolutegravir Formulation Development

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Dolutegravir (MW, 419.38 Da, and 99.99%) was obtained as a gratis sample from Emcure Pharmaceuticals, Gandhinagar, India. Transcutol^® P, Capryol^® 90, Labrasol^®, and Labrafil^® M were purchased from Gattefosse, Saint-Priest, France, and were of USP-NF/EP quality. Dill oil (95.9%) and corn oil (92.3%) were gifted from Vicci Win Pharma, Ahmedabad, India. Castor oil (88.5%) was gifted from Gujarat Glycols, Ankhleswar, India. Polyethylene glycol (PEG) 400 (98%), butyl carbitol (92%), and propylene glycol (99%) were gifted from Himedia, Mumbai, India. Tween^® 80 (97.3%), and Tween^® 20 (97.3%) were received as gift samples from Finar Chemical, Ahmedabad, India. All other reagents/chemicals used in this study are of analytical grade.

Nair A.B., Chaudhary S., Jacob S., Patel D., Shinu P., Shah H., Chaudhary A., Aldhubiab B., Almuqbil R.M., Alnaim A.S., Alqattan F, & Shah J. (2023). Intranasal Administration of Dolutegravir-Loaded Nanoemulsion-Based In Situ Gel for Enhanced Bioavailability and Direct Brain Targeting. Gels, 9(2), 130.

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