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Trued system

Manufactured by Siemens

The TrueD system is a laboratory equipment product developed by Siemens. It is designed to perform precise and accurate measurements and analysis. The core function of the TrueD system is to provide reliable and consistent data for research and testing purposes. The specific technical details and intended applications of the TrueD system are not available within the scope of this request.

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2 protocols using trued system

1

Multimodal Imaging of Ground-Glass Nodules

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Imaging equipment: German Siemens Biograph mCT (64) PET/CT scanner. Image acquisition: the patients were required to fast for 4–6 h before examination, and the height, weight, and blood sugar on the day of examination were recorded; PET/CT whole-body imaging was performed 1 h after the imaging agent (18F-FDG, 3.70–5.55 MBq/kg) injection, and was imaged first with low-dose CT and then PET scan. PET imaging was performed at 2 min/bed, about six to seven beds per patient according to their heights. The TrueX + TOF (ultraHD-PET) method was used for image reconstruction, with two iterations and 21 subsets; the matrix was 200 × 200, and the image acquisition mode was 3D. The post-processing workstation TrueD system (Siemens) was used for image evaluation (lung window width 1,200 HU, window level −600 HU, mediastinal window width 350 HU, window level 40 HU).
Then, the HRCT scan was performed on the GGN site under a breath-hold condition. The collection and reconstruction conditions were as follows: the tube voltage was 140 kV, and the tube current was automatically adjusted by caredose software according to human anatomy and tissue density; the rotation time was 0.5 s, the pitch was 0.6, the layer thickness was 1.0 mm, the layer interval was 0.5 mm, the matrix was 512 × 512, and the lung and mediastinal windows were set as before.
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2

PET/CT Image Acquisition Protocol for Radiomics

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The image acquisition protocol was developed according to the acquisition protocol based on Imaging Biomarker Standardization Initiative (IBSI) guidelines [37 (link)]. The PET/CT image acquisition instrument was a German Siemens BiographmCT (64) PET/CT machine. The patients fasted for 4–6 h before the examination, and their height, weight, and blood sugar were recorded on the examination day. [18F]FDG was intravenously injected according to the patient's body weight at 3.70–5.55 MBq/kg. The imaging agent was provided by Nanjing Jiangyuan Andico Positron Research and Development Company (radiochemical purity > 95%). The patients underwent PET/CT whole-body imaging after resting in a quiet and comfortable environment for 1 h. The patient was placed in the supine position and kept holding the head with both hands. Imaging lasted for 2 min/bed, and the collection range was from the base of the skull to the middle of the femur. Diagnostic chest CT imaging was performed after the PET/CT scan. After image acquisition, the TrueX + TOF (ultraHD-PET) system was used for image reconstruction. A postprocessing workstation TrueD system (Siemens) was used for image evaluation. Image acquisition parameters are listed in Additional file.
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