Creatinine

Manufactured by Arbor Assays

Sourced in United States

Creatinine is a laboratory assay used to measure the concentration of creatinine in a biological sample. Creatinine is a breakdown product of creatine phosphate in muscle and is cleared from the body by the kidneys. The creatinine assay provides information about kidney function.

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Lab products found in correlation

Kim 1, by R&D Systems (1 mentions) Gen5 image software, by Agilent Technologies (1 mentions)

Close spelling variants of this product

Urinary creatinine detection kit Detect X Serum Creatinine Detection Kit Serum creatinine Plasma creatinine DetectX® Urinary Creatinine Detection Kit DetectX Urinary Creatinine Kit DetectX® Serum Creatinine kit Creatinine Serum Detection Kit

2 protocols using creatinine

Renal Function Assessment After Iodixanol

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Renal function was assessed by determining the serum levels of creatinine (Arbor Assays, Ann Arbor, MI, USA), NGAL (R&D Systems), and KIM-1 (R&D Systems) at 48 h after the iodixanol injection.

Kim B.W., Kim H.J., Kim S.H., Baik H.J., Kang M.S., Kim D.H., Markowitz S.D., Kang S.W, & Bae K.B. (2021). 15-Hydroxyprostaglandin dehydrogenase inhibitor prevents contrast-induced acute kidney injury. Renal Failure, 43(1), 168-179.

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Cytokine and Organ Damage Analysis in Sepsis

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All mice were sacrificed 24 h after CLP and blood collected via cardiac puncture. Samples were centrifuged for 10 min at 4°C with 1000 g. Serum was procured from each sample for analysis. Soluble cytokine concentrations of IL-1β, IL-6, IL-10, MCP-1, TNF-α, and INF-γ were determined using the Bio-Plex 200 System with suspension array kits according to the manufacturer’s instructions (Bio-Rad). All samples were run in duplicate. Results were analyzed using the Bio-Plex Manager 3.0 Software. Levels were reported in pg/mL. Organ damage marker concentrations were obtained from serum by ELISA using the BioTek Synergy HT plate reader (BioTek). These markers included ALT (ABclonal), AST (Abcam), and creatinine (Arbor Assays). All kits were used according to the respective manufacturer’s instructions. Results were analyzed using Gen5 Image+ software (BioTek). Levels were reported in pg/dL and mg/dL.

Zhang W., Anyalebechi J.C., Ramonell K.M., Chen C.W., Xie J., Liang Z., Chihade D.B., Otani S., Coopersmith C.M, & Ford M.L. (2021). TIGIT modulates sepsis-induced immune dysregulation in mice with preexisting malignancy. JCI Insight, 6(11), e139823.

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