Pantrk clone epr17341

Manufactured by Abcam

Sourced in Germany

PanTRK (clone EPR17341) is a recombinant rabbit monoclonal antibody directed against the pan-Trk (NTRK1/2/3) receptor tyrosine kinases. The antibody can be used in various immunoassay applications to detect NTRK1/2/3 expression.

Automatically generated - may contain errors

Lab products found in correlation

Bond 3 staining system, by Leica (1 mentions) Ki 67 clone 30 9, by Roche (1 mentions) P63 clone 4a4, by Roche (1 mentions) P53 do 7, by Agilent Technologies (1 mentions) Desmin clone de u 10, by Merck Group (1 mentions) H caldesmon clone h cd, by Agilent Technologies (1 mentions)

2 protocols using pantrk clone epr17341

Immunohistochemical Staining Protocols

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Immunohistochemical stainings were performed as described previously [52] (link), using the monoclonal primary anti-NUT antibody (clone C52B1, 1:200, Cell Signaling Technology, Danvers, MA, USA) and the monoclonal anti-NR4A3 (NOR-1) antibody (clone H-7, 1:25, Santa Cruz Biotechnology, Inc, Dallas, TX, USA), applying the automated Leica Bond III staining system (Leica Biosystems, Nussloch, Germany). The Ventana Benchmark staining system (Oro Valley, AZ, USA) was applied for the following primary antibodies: p63 (clone 4A4, prediluted, Ventana, Oro Valley, AZ, USA), p40 (clone BC24, 1:100, Zytomed Systems, Berlin, Germany), panTRK (clone EPR17341, 1:100, Abcam, Cambridge, UK), CD117 (clone YR145, 1:200, Cell Marque Lifescreen Ltd., Rocklin, CA, USA), Ki-67 (clone 30-9, prediluted, Ventana, Oro Valley, AZ, USA), S100 (polyclonal, 1:2000, DAKO A/S, Jena, Germany), DOG-1 (clone SP31, 1:50 Invitrogen, Carlsbad, CA, USA).

Freiberger S.N., Brada M., Fritz C., Höller S., Vogetseder A., Horcic M., Bihl M., Michal M., Lanzer M., Wartenberg M., Borner U., Bode P.K., Broglie M.A., Rordorf T., Morand G.B, & Rupp N.J. (2021). SalvGlandDx – a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets. Neoplasia (New York, N.Y.), 23(5), 473-487.

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Immunohistochemical Profiling of Soft Tissue

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Immunohistochemistry was performed on 4 μm thick formalin-fixed paraffin-embedded (FFPE) tissue for pan-TRK (clone EPR17341, 1:300, Abcam, Cambridge, MA), S100 (polyclonal, 1:3000, Dako, Carpinteria, CA), SOX10 (clone EP268, 1:2000, Cell Marque, Rocklin, CA), CD34 (clone M7165, 1:150, Dako), desmin (clone DE-U-10, 1:5000, Sigma-Aldrich, Saint Louis, MO), smooth muscle actin (SMA, clone 1A4, 1:20 000, Sigma), h-caldesmon (clone h-CD, 1:300, Dako), estrogen receptor (ER, clone SP1, 1:40, Fisher Scientific, Hampton, NH), progesterone receptor (PR, PgR636, 1:200, Dako), and p53 (DO-7, 1:500, Dako).

Costigan D.C., Nucci M.R., Dickson B.C., Chang M.C., Song S., Sholl L.M., Hornick J.L., Fletcher C.D, & Kolin D.L. (2022). NTRK-Rearranged Uterine Sarcomas: Clinicopathologic Features of 15 Cases, Literature Review, and Risk Stratification. The American journal of surgical pathology.

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