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Tomo slides

Manufactured by Matsunami
Sourced in Japan

TOMO slides are specialized laboratory equipment used for the analysis and manipulation of biological samples. The core function of TOMO slides is to provide a controlled and standardized environment for the observation and study of cells, tissues, or other biological materials under a microscope.

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Lab products found in correlation

2 protocols using tomo slides

1

Histological Grading of Tumor Samples

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In-house tumors and control tissues were fixed in 10% neutral-buffered formalin and embedded in paraffin. Tumors obtained from other institutions had been processed in different devices, however, with the same formalin concentration. Tumors and control tissue blocks were cut in 4 µm sections, mounted on TOMO slides (Matsunami Glass IND Ltd., Osaka, Japan) and dried for 1 h at 50 °C. Haematoxylin and eosin (H & E) staining was performed on all sections for diagnostic confirmation of tumor type. Clear cell renal cell carcinomas, pheochromocytomas, pancreatic neuroendocrine tumors, and extra-adrenal paragangliomas were histologically graded according to the following grading systems: World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grading system [15 (link)], Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) [16 (link)], WHO grading system [17 ], and for paragangliomas again the Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) [16 (link)].
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2

Immunohistochemical Analysis of Prostate Cores

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Four micron sections from B, C and D cores for IHC were placed on either SuperFrost plus slides (PSA, ERG, Vimentin stains) or TOMO slides (Matsunami glass Ind., Ltd) (2IHC stain) using automated Bond III technology (PSA, ERG and Vimentin) or Ventana Benchmark GX technology ("2IHC" CK5/6, p63 and AMACR cocktail) (Fimlab) (detailed protocol in Supplemental Methods). The IHC sections were counterstained with hematoxylin.
Overall immunohistochemistry results were compared for each trio of BCD IHC sections (4core study) or BC IHC sections (3-core study) by two pathologists (T.T. and G.S.B.).
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