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Cl 387 785

Manufactured by Selleck Chemicals
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Sourced in United States

CL-387,785 is a laboratory instrument used for chemical analysis and research. It is designed to perform specific measurements and tasks related to the identification and quantification of chemical compounds. The core function of CL-387,785 is to provide accurate and reliable data, but its intended use is not interpreted or extrapolated in this description.

Automatically generated - may contain errors

Lab products found in correlation

Trametinib, by Selleck Chemicals (2 mentions) Dabrafenib, by Selleck Chemicals (2 mentions) Plx4720, by Selleck Chemicals (2 mentions) Sch772984, by Selleck Chemicals (2 mentions) Gefitinib, by Selleck Chemicals (1 mentions) Neratinib, by Selleck Chemicals (1 mentions) Afatinib, by Selleck Chemicals (1 mentions)

3 protocols using cl 387 785

1

Inhibition of Oncogenic Pathways

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BRAF inhibitors dabrafenib and PLX4720, MEK inhibitor trametinib, ERK
inhibitor SCH772984 and EGFR tyrosine kinase inhibitor CL-387,785 were purchased
from Selleck Chemicals (Houston, TX, USA). Dacarbazine was obtained from the
pharmacy of the Slotervaart hospital (Amsterdam, The Netherlands).
Kong X., Kuilman T., Shahrabi A., Boshuizen J., Kemper K., Song J.Y., Niessen H.W., Rozeman E.A., Geukes Foppen M.H., Blank C.U, & Peeper D.S. (2017). Cancer Drug Addiction is Relayed by an ERK2-Dependent Phenotype Switch. Nature, 550(7675), 270-274.
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2

Synthesis and Acquisition of EGFR Inhibitors

Cited 1 time
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WZ4002, AZD9291 and CO-1686 were synthesized using previously published methods (14 (link)–16 ). Gefitinib, Afatinib, Neratinib, CL-387,785 were obtained from Selleck chemicals. The synthesis of TX2-30 is described in supplementary methods. Stock solutions of all drugs were prepared in DMSO and stored at −80°C.
Ercan D., Choi H.G., Yun C.H., Capelletti M., Xie T., Eck M.J., Gray N.S, & Jänne P.A. (2015). EGFR mutations and resistance to Irreversible pyrimidine based EGFR inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research, 21(17), 3913-3923.
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3

Inhibition of Oncogenic Pathways

Check if the same lab product or an alternative is used in the 5 most similar protocols
BRAF inhibitors dabrafenib and PLX4720, MEK inhibitor trametinib, ERK
inhibitor SCH772984 and EGFR tyrosine kinase inhibitor CL-387,785 were purchased
from Selleck Chemicals (Houston, TX, USA). Dacarbazine was obtained from the
pharmacy of the Slotervaart hospital (Amsterdam, The Netherlands).
Kong X., Kuilman T., Shahrabi A., Boshuizen J., Kemper K., Song J.Y., Niessen H.W., Rozeman E.A., Geukes Foppen M.H., Blank C.U, & Peeper D.S. (2017). Cancer Drug Addiction is Relayed by an ERK2-Dependent Phenotype Switch. Nature, 550(7675), 270-274.
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