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Onetouch ultra glucometer

Manufactured by LifeScan
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The OneTouch Ultra glucometer is a portable device used for measuring blood glucose levels. It provides users with accurate and reliable readings to help manage their diabetes.

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Lab products found in correlation

Humulin r, by Eli Lilly (8 mentions) Ultra sensitive mouse insulin elisa kit, by Crystal Chem (7 mentions) Onetouch ultra strips, by LifeScan (6 mentions) Comprehensive lab animal monitoring system, by Columbus Instruments (4 mentions) Sensitive rat insulin ria kit, by Merck Group (3 mentions) Mmhmag 44k milliplex map mouse metabolic hormone magnetic bead panel metabolism multiplex assay, by Merck Group (3 mentions) Pefabloc sc, by Roche (3 mentions) Protease inhibitor, by Merck Group (3 mentions) Novolin r, by Novo Nordisk (3 mentions) Diastix, by Bayer (3 mentions) Comprehensive laboratory monitoring system, by Columbus Instruments (3 mentions) Dpp4 inhibitor, by Merck Group (3 mentions) Humulin regular, by Eli Lilly (2 mentions) D glucose, by Merck Group (2 mentions) Insulin, by Eli Lilly (2 mentions) Echomri 100, by Echo Medical Systems (2 mentions) Stz mice, by Jackson ImmunoResearch (2 mentions) Humulin, by Eli Lilly (2 mentions) Ethylene diamine tetraacetic acid (edta), by Merck Group (2 mentions) Novorapid, by Novo Nordisk (2 mentions)

Spelling variants of this product

OneTouch Ultra (231 citations) OneTouch glucometer (57 citations) Glucometer (28 citations) OneTouch Ultra-portable glucometer (6 citations)

124 protocols using onetouch ultra glucometer

1

Metabolic Profiling of Glucose and Insulin Homeostasis

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Glucose tolerance tests (GTT) were conducted after o/n fasting. Mice were injected i.p. with 1 g of glucose per/kg bodyweight and blood glucose was monitored at 0, 15, 30, 60, and 120 min using a OneTouch Ultra glucometer (Lifescan Inc). Insulin tolerance tests (ITT) were conducted after 3 hr fasting. Mice were injected i.p. with 2U of insulin/kg bodyweight (Humulin R; Eli Lilly) and blood glucose was monitored at 0, 15, 30, 60, and 90 min using a OneTouch Ultra glucometer (Lifescan Inc). Real-time metabolic analyses were conducted in a Comprehensive Lab Animal Monitoring System (Columbus Instruments). CO2 production, O2 consumption, RQ (relative rates of carbohydrate versus fat oxidation), and ambulatory counts were determined for six consecutive days and nights, with at least 24 h for adaptation before data recording. Total body composition analysis was performed using an EchoMRI-100™ (Echo Medical Systems, LLC).
Suh J.M., Jonker J.W., Ahmadian M., Goetz R., Lackey D., Osborn O., Huang Z., Liu W., Yoshihara E., van Dijk T., Havinga R., Fan W., Yin Y.Q., Yu R.T., Liddle C., Atkins A.R., Olefsky J.M., Mohammadi M., Downes M, & Evans R.M. (2014). Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature, 513(7518), 436-439.
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2

Metabolic Profiling of Glucose and Insulin Homeostasis

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Glucose tolerance tests (GTT) were conducted after o/n fasting. Mice were injected i.p. with 1 g of glucose per/kg bodyweight and blood glucose was monitored at 0, 15, 30, 60, and 120 min using a OneTouch Ultra glucometer (Lifescan Inc). Insulin tolerance tests (ITT) were conducted after 3 hr fasting. Mice were injected i.p. with 2U of insulin/kg bodyweight (Humulin R; Eli Lilly) and blood glucose was monitored at 0, 15, 30, 60, and 90 min using a OneTouch Ultra glucometer (Lifescan Inc). Real-time metabolic analyses were conducted in a Comprehensive Lab Animal Monitoring System (Columbus Instruments). CO2 production, O2 consumption, RQ (relative rates of carbohydrate versus fat oxidation), and ambulatory counts were determined for six consecutive days and nights, with at least 24 h for adaptation before data recording. Total body composition analysis was performed using an EchoMRI-100™ (Echo Medical Systems, LLC).
Suh J.M., Jonker J.W., Ahmadian M., Goetz R., Lackey D., Osborn O., Huang Z., Liu W., Yoshihara E., van Dijk T., Havinga R., Fan W., Yin Y.Q., Yu R.T., Liddle C., Atkins A.R., Olefsky J.M., Mohammadi M., Downes M, & Evans R.M. (2014). Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature, 513(7518), 436-439.
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3

Diabetic Mice Glucose Response

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STZ mice (Jackson Laboratory) injected sc with control PBS or 0.5mg/kg rFGF1 were subsequently fasted for 8 hrs prior to blood glucose measurements (OneTouch Ultra glucometer, Lifescan Inc). STZ mice injected sc with control PBS or 0.5mg/kg rFGF1 were subsequently fasted for 8 hrs prior to injection of 0.25U/kg insulin (Humulin R; Eli Lilly) and blood glucose was monitored at 0, 30, 60, and 120 min (OneTouch Ultra glucometer, Lifescan Inc).
Suh J.M., Jonker J.W., Ahmadian M., Goetz R., Lackey D., Osborn O., Huang Z., Liu W., Yoshihara E., van Dijk T., Havinga R., Fan W., Yin Y.Q., Yu R.T., Liddle C., Atkins A.R., Olefsky J.M., Mohammadi M., Downes M, & Evans R.M. (2014). Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature, 513(7518), 436-439.
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4

Diabetic Mice Glucose Response

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STZ mice (Jackson Laboratory) injected sc with control PBS or 0.5mg/kg rFGF1 were subsequently fasted for 8 hrs prior to blood glucose measurements (OneTouch Ultra glucometer, Lifescan Inc). STZ mice injected sc with control PBS or 0.5mg/kg rFGF1 were subsequently fasted for 8 hrs prior to injection of 0.25U/kg insulin (Humulin R; Eli Lilly) and blood glucose was monitored at 0, 30, 60, and 120 min (OneTouch Ultra glucometer, Lifescan Inc).
Suh J.M., Jonker J.W., Ahmadian M., Goetz R., Lackey D., Osborn O., Huang Z., Liu W., Yoshihara E., van Dijk T., Havinga R., Fan W., Yin Y.Q., Yu R.T., Liddle C., Atkins A.R., Olefsky J.M., Mohammadi M., Downes M, & Evans R.M. (2014). Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature, 513(7518), 436-439.
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5

Plasma Metabolic Hormone Analysis in Mice

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At 12 weeks post-surgery all mice were overnight fasted and euthanized by decapitation. 500 µl of trunk blood was collected in microtubes containing 83.5 µl EDTA (Sigma, St. Louis, MO) and 15 µl of a Protease inhibitor cocktail (5 µl of each of the following: Protease inhibitor, Sigma, St. Louis, MO; DPP-IV inhibitor, EMD Millipore, St. Charles, MO; Pefabloc SC, Roche, Indianapolis, IN) and immediately centrifuged at 4° C and 3000 RPM for 10 minutes to separate the plasma from the whole blood. Plasma aliquots were frozen in liquid nitrogen, and stored at −80° C prior to processing. Plasma was subjected to ELISA for measurement of insulin and leptin concentrations (MMHMAG-44K Milliplex map mouse metabolic hormone magnetic bead panel – metabolism multiplex assay, EMD Millipore, St. Charles, MO). One drop of unprocessed tail vein blood was used for baseline glucose measurement (Onetouch Ultra Glucometer, LifeScan INC, Milpitas, CA; Onetouch Ultra Strips, LifeScan INC, Milpitas, CA). One drop of unprocessed trunk blood was used for baseline glucose measurement (Onetouch Ultra Glucometer, LifeScan INC, Milpitas, CA; Onetouch Ultra Strips, LifeScan INC, Milpitas, CA).
Hao Z., Townsend R.L., Mumphrey M.B., Morrison C.D., Münzberg H, & Berthoud H.R. (2017). RYGB produces more sustained body weight loss and improvement of glycemic control compared with VSG in the diet-induced obese mouse model. Obesity surgery, 27(9), 2424-2433.
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6

Glucose and Insulin Measurement

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Blood glucose levels were measured by OneTouch Ultra glucometers (LifeScan, Milpitas, CA, USA), and plasma insulin levels were determined by the Sensitive Rat Insulin RIA Kit (Millipore, Billerica, MA, USA).
Benova A., Ferencakova M., Bardova K., Funda J., Prochazka J., Spoutil F., Cajka T., Dzubanova M., Balcaen T., Kerckhofs G., Willekens W., van Lenthe G.H., Alquicer G., Pecinova A., Mracek T., Horakova O., Rossmeisl M., Kopecky J, & Tencerova M. (2022). Novel thiazolidinedione analog reduces a negative impact on bone and mesenchymal stem cell properties in obese mice compared to classical thiazolidinediones. Molecular Metabolism, 65, 101598.
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7

Glucose and Insulin Tolerance Tests

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For GTT experiment, mice were fasted for 8 h and measured fasting blood glucose on tail vein using OneTouch Ultra glucometers (LifeScan). Then the mice were injected with 1 g/kg glucose intraperitoneally and blood glucose was recorded at 15, 30, 60, and 120 min. For ITT experiment, mice fasted for 6 h and measured fasting blood glucose. Then the mice were injected with 0.75 U/kg insulin subcutaneously and blood glucose was recorded at 15, 30, 60, 120 min.
Fang Z., Xu H., Duan J., Ruan B., Liu J., Song P., Ding J., Xu C., Li Z., Dou K, & Wang L. (2023). Short-term tamoxifen administration improves hepatic steatosis and glucose intolerance through JNK/MAPK in mice. Signal Transduction and Targeted Therapy, 8, 94.
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8

Glucose and Insulin Tolerance Tests in Mice

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At the end of week 21, mice were fasted for either 18 h for a glucose tolerance test or 6 h for an insulin tolerance test. Blood was acquired from the tail vein and the fasting blood glucose level were measured (time 0) using One-Touch Ultraglucometers (Life Scan). The animals were then given either 2 g/kg glucose or 0.75 U/kg insulin (Regular Humulin, Eli Lilly and Company) by intraperitoneal injection. Blood glucose curves were drawn based on the glucose in blood samples drawn at 15 min, 30 min, 60 min, and 120 min post injection, and the area under the curve (AUC) was calculated.
Li H., Li J., Qu Z., Qian H., Zhang J., Wang H., Xu X, & Liu S. (2020). Intrauterine exposure to low-dose DBP in the mice induces obesity in offspring via suppression of UCP1 mediated ER stress. Scientific Reports, 10, 16360.
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9

Glucose and Insulin Tolerance Tests

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The mice were fasted for 18 h before the glucose tolerance test, and they were fasted for 6 h before insulin tolerance test. The mice were injected intraperitoneally with either 2 g kg−1 glucose or 0.75 U kg−1 insulin (Regular Humulin, Eli Lilly and Company). The glucose measurements were taken up to 2 h post injection using One-Touch Ultra glucometers (LifeScan). The serum insulin levels were measured by a mouse insulin ELISA kit (Crystal Chem).
Jiang X., Cao Y., Li F., Su Y., Li Y., Peng Y., Cheng Y., Zhang C., Wang W, & Ning G. (2014). Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours. Nature Communications, 5, 5809.
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10

Quantification of Plasma and Hepatic Lipids

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Plasma levels of (i) TAG and total cholesterol were determined using the colorimetric enzymatic assays from Erba Lachema (Brno, Czech Republic), and (ii) NEFAs were assessed with a NEFA-HR(2) kit from Waco Chemicals GmbH (Neuss, Germany). Blood glucose levels were measured by OneTouch Ultra glucometers (LifeScan, Milpitas, CA, USA), and plasma insulin levels were determined by the Sensitive Rat Insulin RIA Kit (Millipore, Billerica, MA, USA). Liver TAG content was estimated in ethanolic KOH tissue solubilisates as before [13 (link)].
Bardova K., Funda J., Pohl R., Cajka T., Hensler M., Kuda O., Janovska P., Adamcova K., Irodenko I., Lenkova L., Zouhar P., Horakova O., Flachs P., Rossmeisl M., Colca J, & Kopecky J. (2020). Additive Effects of Omega-3 Fatty Acids and Thiazolidinediones in Mice Fed a High-Fat Diet: Triacylglycerol/Fatty Acid Cycling in Adipose Tissue. Nutrients, 12(12), 3737.
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