C57BL/6J mouse pups (Jackson Laboratory, Bar Harbor, ME) were monitored until birth then placed into chambers with varying levels of hyperoxia (40%, 60%, or 80%) or room air control (RA) from within 12 hours birth until postnatal day eight. Animals were housed in a specialized inhalation facility on 12-hour light-dark cycles with ad libitum standard food and water. Temperature and humidity were monitored throughout the exposure. Animals were recovered in RA until their respective analysis endpoints. Nursing dams were rotated every 24 hours.
C57bl 6j mouse pups
Manufactured by Jackson ImmunoResearch
Sourced in Montenegro
C57BL/6J mouse pups are laboratory mouse strains commonly used in research. They are genetically defined and widely used as experimental models.
Automatically generated - may contain errors
Lab products found in correlation
3 protocols using c57bl 6j mouse pups
1
Hyperoxia Exposure in Newborn Mice
2
Hyperoxia Exposure in Newborn Mice
3
Neonatal PD1 Knockout Mouse Model
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Wild type (WT) C57BL/6J mouse pups were bred from adult mice (Jackson Laboratory, Bar Harbor, ME). Wild type mice deficient in PD1 (PD1−/−) were used to breed the knock-out pups (kindly provided by Tasuku Honjo, Kyoto University, Kyoto, Japan, through Megan Sykes at Massachusetts General Hospital, Boston, MA). Mice were bred at the Rhode Island Hospital (RIH) rodent facility and received standard care and diet ad libitum. Neonatal pups between 5 and 7 days old were utilized for each experiment in accordance with the Institutional Animal Care and Use Committee of Rhode Island Hospital (AWC# 5064-18), the Animal Welfare Act, and National Institutes of Health guidelines for animal care and use.
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