All protocols for animal use and euthanasia were reviewed and approved by the Animal Care Committee of the Joslin Diabetes Center. The experiments were in accordance with National Institutes of Health (NIH) guidelines following the standards established by the Animal Welfare Acts and by the documents entitled ‘Principles for Use of Animals’ and ‘Guide for the Care and Use of Laboratory Animals’. Male Zucker lean (ZL) rats, Zucker fatty (ZF) rats, Zucker diabetic fatty (ZDF) and their control (LEAN +/?) were from Charles River (Wilmington, MA, USA). C57BL/6 mice were from Jackson Laboratory (Bar Harbor, ME, USA). PDGF-BB was purchased from Sigma (St Louis, MO, USA).
Male zucker lean rats
Manufactured by Charles River Laboratories
Sourced in United States
Male Zucker lean (ZL) rats are a commonly used rodent model in research. They are characterized by a lean phenotype and serve as a control strain for the Zucker fatty (ZF) rat, which exhibits obesity and other metabolic abnormalities. The male ZL rats provide a healthy, lean reference point for comparative studies.
Automatically generated - may contain errors
2 protocols using male zucker lean rats
1
Zucker Rat Animal Study Protocol
2
Zucker Rat Diabetes Animal Protocol
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