Magnetom prisma system

Manufactured by Siemens

Sourced in Germany

The MAGNETOM Prisma system is a magnetic resonance imaging (MRI) scanner developed by Siemens. It is designed to provide high-quality imaging capabilities for medical and research applications. The MAGNETOM Prisma system utilizes a powerful superconducting magnet and advanced imaging technology to generate detailed images of the human body.

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Lab products found in correlation

32 channel head coil, by Siemens (1 mentions)

Close spelling variants of this product

MAGNETOM Prisma 3T system 3.0 T Magnetom Prisma system MAGNETOM Prisma Fit system Magnetom Prisma 3T MR system MAGNETOM Prisma MRI System MAGNETOM Prisma 3T MRI system MAGNETOM Prisma Prisma system Prisma

10 protocols using magnetom prisma system

Multimodal MRI Acquisition Protocol

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The MRI scans were acquired on a 3 T Siemens Magnetom Prisma system (Siemens, Erlangen, Germany) equipped with a 64-channel head/neck coil at Scannexus, Maastricht, The Netherlands. T1-weighted Magnetization Prepared Rapid Acquisition Gradient Echo (MPRAGE) whole brain images were acquired with a voxel size of 1.0 mm × 1.0 mm × 1.0 mm (repetition time (TR) = 2250 msec, echo time (TE) = 2.21 msec, flip angle = 9°, field of view (FOV) = 256 × 256, 192 sagittal orientated slices, GRAPPA = 2, no fat suppression, acquisition time (TA) = 5.05 min).
Whole brain structural Diffusion Weighted Imaging scans were acquired using an interleaved echo-planar-imaging sequence (field of view 200 × 200 mm², TR 7300 ms, TE 49 ms, voxel size 2 × 2 × 2 mm³, b-value 1000 s/mm², 72 slices, no overlap). 119 directions were recorded; 11 B0 volumes and 108 B-1000 volumes. Total acquisition time was 14m52s. Due to a scanner update a one scan (PE-group) was recorded with TR 7800 ms.

Michielse S., Lange I., Bakker J., Goossens L., Verhagen S., Wichers M., Lieverse R., Schruers K., van Amelsvoort T., van Os J, & Marcelis M. (2019). White matter microstructure and network-connectivity in emerging adults with subclinical psychotic experiences. Brain Imaging and Behavior, 14(5), 1876-1888.

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Longitudinal Structural Brain Imaging After Trauma

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Whole-brain anatomical images were conducted using a 3T MAGNETOM Prisma system (Siemens Medical Solutions, Erlangen, Germany) at the Tel-Aviv Sourasky Medical Center (TASMC). These repeated structural MRI scans took place at three different time points following traumatic exposure (T1, T2, and T3). At each time point, a sagittal T1-weighted magnetization prepared rapid gradient echo (MPRAGE) sequence (TR/TE = 2400/2.29ms, flip angle = 8°, voxel size = 0.7mm³, field of view = 224×224mm², slice thickness=0.7mm) was used to acquire high-resolution structural images. Foam padding and earplugs were used to reduce head motion and scanner noise.

Ben-Zion Z., Korem N., Spiller T.R., Duek O., Keynan J.N., Admon R., Harpaz-Rotem I., Liberzon I., Shalev A.Y, & Hendler T. (2022). Longitudinal Volumetric Evaluation of Hippocampus and Amygdala Subregions in Recent Trauma Survivors. Molecular psychiatry, 28(2), 657-667.

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5D J-resolved MRSI Phantom Imaging

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The spectroscopic phantom was scanned on a 3T Siemens Magnetom Prisma system using a commercial 20-channel head and neck coil. The data were acquired using the proposed data acquisition scheme with the following parameters: FOV = 180 × 180 × 48 mm³, excitation volume = 90 × 90 × 40 mm³, TR = 1200 ms, nominal spatial resolution = 3.0 × 3.0 × 3.0 mm³, matrix size = 60 × 60 × 16, and 30.7 minutes scan time. The proposed method was used to reconstruct the 5D J-resolved MRSI images for spectral quantification. The metabolite concentrations of vial I were used as reference for calculating the molecule concentrations in all the other vials.

Tang L., Zhao Y., Li Y., Guo R., Clifford B., Fakhri G.E., Ma C., Liang Z.P, & Luo J. (2020). Accelerated J-Resolved 1H-MRSI with Limited and Sparse Sampling of (k, t1, t2)-Space. Magnetic resonance in medicine, 85(1), 30-41.

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Rat Brain Imaging with 3T MRI

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All rats underwent fasting for 12 h and water deprivation for 4 h before scanning. After anesthetized with 3% isoflurane and maintained with 1.5% isoflurane, the rats were placed in the supine position with all 4 limbs immobilized. A Siemens Prisma 3.0 T superconducting scanner with a 64-channel head-coil system (MAGNETOM Prisma System, Siemens Medical Solutions, Erlangen, Germany) was used.

Zhang Q., Yu Z., Zeng S., Liang L., Xu Y., Zhang Z., Tang H., Jiao W., Xue W., Wang W., Zhang X., Jiang T, & Hu X. (2019). Use of intravoxel incoherent motion imaging to monitor a rat kidney chronic allograft damage model. BMC Nephrology, 20, 364.

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Comprehensive Neuroimaging Protocol for Brain Assessment

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All participants underwent a comprehensive neuroimaging protocol (Nation et al., 2018 (link)) and all MRI scans were conducted on a 3T scanner (Siemens MAGNETOM Prisma System). The following sequences were examined for the current analysis: 3D T1-weighted anatomical scan for qualitative assessment of brain structures and abnormalities (Scan parameters: TR = 2300 ms; TE = 2.98 ms; TI = 900 ms; flip angle = 9 deg; FOV = 256 mm; resolution = 1.0 × 1.0 × 1.2 mm³; Scan time = 9 minutes), T2-weighted scan for identification of perivascular spaces (Scan parameters: TR = 10000 ms; TE = 88.0 ms; flip angle = 120 deg; FOV = 210 mm; resolution = 0.8 × 0.8 × 3.5 mm³; Echo spacing = 9.8 ms; Echo trains per slice = 11; Scan time = 2 minutes), and 3D gradient and spin-echo (GRASE) pseudo-continuous arterial spin labeling (pCASL) for CBF. The scan parameters were as follows for pCASL: TR = 5000 ms; TE at University of Southern California = 36.3 ms; TE at University of California, Irvine = 37.46 ms; FOV = 240 mm; resolution = 2.5 × 2.5 × 3.4 mm³; slice thickness = 3.42 mm; number of slices = 24; labeling duration = 1517 ms; post-labeling delay = 2000 ms. There was a total of 32 acquisitions (1 M0 image + 1 dummy image + 30 alternating tag and control images), with a total scan time of 5 minutes 25 seconds, yielding 15 tag-control pair images.

Alroy J., Marshall C.R., Bambach R.K., Bezusko K., Foote M., Fürsich F.T., Hansen T.A., Holland S.M., Ivany L.C., Jablonski D., Jacobs D.K., Jones D.C., Kosnik M.A., Lidgard S., Low S., Miller A.I., Novack-Gottshall P.M., Olszewski T.D., Patzkowsky M.E., Raup D.M., Roy K., Sepkoski JJ J.r., Sommers M.G., Wagner P.J, & Webber A. (2001). Effects of sampling standardization on estimates of Phanerozoic marine diversification. Proceedings of the National Academy of Sciences of the United States of America, 98(11), 6261-6266.

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Large-Scale fMRI Scanning Protocol

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fMRI data were acquired with a 3-Tesla Siemens MAGNETOM Prisma system (Siemens Medical Systems, Erlangen, Germany). The scanner was equipped with a 64-channel phased-array head/neck coil. We used inflatable air pads to restrict head movement, and participants were instructed to lie still for the duration of the scan. For the applicability in large-scale testing, we decided on a standard fMRI scanning protocol: we acquired two task fMRI sessions of 140 volumes using echo-planar imaging (EPI), including four dummies. Each volume consisted of 32 axial slices of 3-mm thickness with a 0.75-mm gap. The repetition time (TR) was 2,000 ms, echo time (TE) was 30 ms, flip angle was 84°, readout bandwidth was 2,300 Hz/pixel, the slice orientation was anterior commissure–posterior commissure (AC-PC), and field of view (FOV) was 192 × 192 mm, resulting in an effective voxel size of 3.0 × 3.0 × 3.75 mm.

Boenniger M.M., Diers K., Herholz S.C., Shahid M., Stöcker T., Breteler M.M, & Huijbers W. (2021). A Functional MRI Paradigm for Efficient Mapping of Memory Encoding Across Sensory Conditions. Frontiers in Human Neuroscience, 14, 591721.

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High-Resolution 3T MEMPR Neuroimaging

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Neuroimaging was acquired on a 3T Siemens MAGNETOM Prisma system with a 32-channel head coil. For optimal contrast, a multi-echo MPRAGE (MEMPR) sequence was collected with the following parameters: TR/TE/TI=2400/2.07/1000 ms, flip angle=8°, FoV=256×256 mm, Slice thickness=0.8 mm, Slices per slab=224, 3D voxel resolution=0.8×0.8×0.8 mm, Pixel bandwidth=240 Hz. A fieldmap for distortion correction was also acquired: TR/TE=7220 ms/73 ms, FoV=248×248 mm, in-plane voxel resolution=3.0×3.0×3.0 mm, 56 slices.

Thayer R.E., YorkWilliams S.L., Hutchison K.E, & Bryan A.D. (2019). Preliminary Results from a Pilot Study Examining Brain Structure in Older Adult Cannabis Users and Nonusers. Psychiatry research. Neuroimaging, 285, 58-63.

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Multimodal MRI Acquisition Protocol

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The MRI acquisition was performed using the 3T Siemens MAGNETOM Prisma system (Siemens, Erlangen, Germany). T1w images were acquired using the magnetization-prepared rapid gradient-echo (MPRAGE) sequence, with voxel size = 1 × 1 × 1 mm³, repetition time = 2,150 ms, echo time (TE) = 2.47 ms, inversion time = 1,000 ms, generalized autocalibrating partial parallel acquisition = 2, and flip angle = 8°. The acquisition of T2w images was based on the SPACE sequence, with voxel size = 1 × 1 × 1 mm³, TE = 147 ms, and generalized autocalibrating partial parallel acquisition = 2. No prescan normalization algorithm as implemented by the manufacturer was used in T1w or T2w scans. Finally, the pseudocontinuous arterial spin labeling sequence was acquired with a repetition time = 5,000 ms, TE = 14 ms, field of view = 210 × 210 mm², voxel size = 3 × 3 × 3 mm³, number of slices = 36 with 20% gap, labeling plane thickness = 10 mm, labeling plane offset = 90 mm, labeling duration = 1,600 ms, labeling postlabeling delay = 1,600 ms, and number of pairs of label/control images = 80 (in 10 subjects, the number of label/control pairs was 79). The metabolic condition during the MRI acquisition was controlled using a hyperinsulinemic clamp to maintain blood glucose level of ∼95 mg/dL (for details of the procedure, see Mangia et al. [29 (link)]).

Filip P., Canna A., Moheet A., Bednarik P., Grohn H., Li X., Kumar A.F., Olawsky E., Eberly L.E., Seaquist E.R, & Mangia S. (2020). Structural Alterations in Deep Brain Structures in Type 1 Diabetes. Diabetes, 69(11), 2458-2466.

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Quantifying Liver Fat Changes with Liraglutide

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All subjects received upper-abdominal MRI examinations to accurately measure liver fat content before and after the 12-week liraglutide treatment. Each subject underwent an upper-abdominal MRI examination with a 3-Tesla whole-body human MRI scanner (MAGNETOM Prisma System; Siemens Medical Solutions, Erlangen, Germany) while in the supine position. Subjects were instructed to follow a 10 to 12 h overnight fast before imaging. The scanning protocol comprised an initial set of localizer images and then a T1 volumetric interpolated breath-hold examination (VIBE) Dixon sequence. The scans covered all upper abdominal organs, including liver and pancreas. The imaging parameters were as follows: TE1 1.23 ms, TE2 2.46 ms, TR 3.97 ms, 9° flip angle, Bandwidth1 1040 Hz/Px, Bandwidth2 1040 Hz/Px, and a slice thickness of 3.0 mm. All subjects were carefully instructed to hold their breath during end expiration to ensure consistency.

Li X., Wu X., Jia Y., Fu J., Zhang L., Jiang T., Liu J, & Wang G. (2021). Liraglutide Decreases Liver Fat Content and Serum Fibroblast Growth Factor 21 Levels in Newly Diagnosed Overweight Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Disease. Journal of Diabetes Research, 2021, 3715026.

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Prisma MRI Acquisition Protocol

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MRI data were acquired using the 3-T Siemens MAGNETOM Prisma system from the Beijing Tiantan Hospital and First Affiliated Hospital Affiliated with Xiamen University. Details of the MRI acquisition parameters are shown in Appendix S2.

Wan H., Liu Q., Chen C., Dong W., Wang S., Shi W., Li C., Ren J., Wang Z., Cui T, & Shao X. (2023). An Integrative Nomogram for Identifying Cognitive Impairment Using Seizure Type and Cerebral Small Vessel Disease Neuroimaging Markers in Patients with Late-Onset Epilepsy of Unknown Origin. Neurology and Therapy, 13(1), 107-125.

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