Two studies were conducted under the Institutional Animal Care and Use Committee approved Animal Care and Use Protocol procedures at Mayo Clinic (Rochester, MN) and Bristol Myers Squibb (BMS, Lawrenceville, NJ). The investigative procedures regarding diet and treatment groups were conducted in the same manner at both sites, as follows: 6-week-old, male C57BL/6J mice were purchased from Jackson Laboratories (Bar Harbor, ME) and acclimated to either the BMS (single-housed, N = 36) or Mayo Clinic animal facilities (group-housed, 3–4 per cage, N = 42) for 1 week on standard rodent chow (BMS: Teklad, 2018, Madison, WI; Mayo Clinic: Lab Diet 5053 PicoLab® Rodent Diet-20; St. Louis, MO). At 7 weeks of age, mice of normal body weight (~22–24 g) were randomized to receive either a matched control diet (CD) containing standard levels of choline, methionine, and fat (Research Diets, A13012807, New Brunswick, NJ) or a choline-deficient, amino acid-defined, (methionine, 0.1%), high-fat (60% of calories from fat) diet (CDAHFD; Research Diets, A06071302, New Brunswick, NJ).10 –12 ,33 (link)
A13012807
Manufactured by Research Diets
A13012807 is a laboratory equipment item. It is designed to perform specific functions within a research or testing environment. The core function of this product is to facilitate controlled experiments or analyses, but a more detailed description cannot be provided while maintaining an unbiased and factual approach.
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Lab products found in correlation
2 protocols using a13012807
1
Dietary Intervention in C57BL/6J Mice
2
Dietary Effects on C57BL/6J Mice
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Two studies were conducted under the Institutional Animal Care and Use Committee approved Animal Care and Use Protocol procedures at Mayo Clinic (Rochester, MN) and Bristol Myers Squibb (BMS, Lawrenceville, NJ). The investigative procedures regarding diet and treatment groups were conducted in the same manner at both sites, as follows: 6‐week‐old, male C57BL/6J mice were purchased from Jackson Laboratories (Bar Harbor, ME) and acclimated to either the BMS (single‐housed, N = 36) or Mayo Clinic animal facilities (group‐housed, 3–4 per cage, N = 42) for 1 week on standard rodent chow (BMS: Teklad, 2018, Madison, WI; Mayo Clinic: Lab Diet 5053 PicoLab® Rodent Diet‐20; St. Louis, MO). At 7 weeks of age, mice of normal body weight (~22–24 g) were randomized to receive either a matched control diet (CD) containing standard levels of choline, methionine, and fat (Research Diets, A13012807, New Brunswick, NJ) or a choline‐deficient, amino acid‐defined, (methionine, 0.1%), high‐fat (60% of calories from fat) diet (CDAHFD; Research Diets, A06071302, New Brunswick, NJ).10 , 11 , 12 , 33
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