Cd11ccre gfp

Manufactured by Jackson ImmunoResearch

The CD11cCre-GFP is a transgenic mouse line that expresses Cre recombinase under the control of the CD11c promoter, which drives expression in dendritic cells. The Cre recombinase is fused to green fluorescent protein (GFP), allowing for the visualization of Cre-expressing cells.

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Lab products found in correlation

Igf1fl fl, by Jackson ImmunoResearch (1 mentions) B6 thy1, by Jackson ImmunoResearch (1 mentions) B6 nr4a1egfp nur77gfp, by Jackson ImmunoResearch (1 mentions) B6 mhc 2, by Jackson ImmunoResearch (1 mentions) Cd4ko, by Jackson ImmunoResearch (1 mentions)

2 protocols using cd11ccre gfp

Murine Models for Neuroinflammation Studies

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C57BL/6j bom female mice aged 7–8 weeks were obtained from Taconic Europe A/S; CX3CR1^GFP/GFP and CCR2^RFP/RFP, CD11c^Cre‐GFP (Stranges et al, 2007) and Igf1^fl/fl were obtained from The Jackson Laboratory and maintained as a breeding colony (CX3CR1^GFP/GFP and CCR2^RFP/RFP were crossed with B6 mice to obtain heterozygotes) in the Biomedical Laboratory, University of Southern Denmark (Odense). All experiments performed in Denmark were approved by the Danish Animal Experiments Inspectorate (approval number 2014‐15‐0201‐00369). CX3CR1^CreER, CD11c^Cre, DTA, and iDTR mice were housed in specific pathogen‐free conditions and used in accordance with the guidelines of the Central Animal Facility Institution (ZVTE, University of Mainz). Neonatal mice (p2‐p21) used for experiments were of mixed sex.

Wlodarczyk A., Holtman I.R., Krueger M., Yogev N., Bruttger J., Khorooshi R., Benmamar‐Badel A., de Boer‐Bergsma J.J., Martin N.A., Karram K., Kramer I., Boddeke E.W., Waisman A., Eggen B.J, & Owens T. (2017). A novel microglial subset plays a key role in myelinogenesis in developing brain. The EMBO Journal, 36(22), 3292-3308.

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Diverse Murine Strains for Immunology

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C57Bl/6 (B6), B6.CD45.1, B6.Thy1.1, B6.Nr4a1^eGFP (Nur77^GFP), B6.CD80/CD86 KO, IL-15Ra KO, CD11c-Cre-GFP, I-AB-flox, CD4 KO and B6.MHC II⁻ were obtained from the Jackson Laboratory. B6.TCRα/β KO mice were obtained from R.Welsh (UMass Chan), Y-linked B6.OT-II mice from L.Bradley (The Scripps Research Institute, La Jolla, CA) and were originally published by F.Carbone’s group ^{47 (link)}, BALB/c.HNT from D. Lo ^{48 (link)} (The Scripps Research Institute, La Jolla, CA), IFNAR KO from J.Sprent (Garvan Institute), CD11cTg.H2-Ab1^−/− mice from T.Laufer originally and all have been bred and maintained at the UMass Chan animal facility. Mice were at least 8 weeks old prior to use, controls were age and sex-matched, both female and male mice were used where possible. Experimental animal procedures were done in accordance with UMass Chan Animal Care and Use Committee guidelines.

Bussey H., Kaback D.B., Zhong W., Vo D.T., Clark M.W., Fortin N., Hall J., Ouellette B.F., Keng T, & Barton A.B. (1995). The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.. Proceedings of the National Academy of Sciences of the United States of America, 92(9), 3809-3813.

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