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Discovery vct pet ct scanner

Manufactured by GE Healthcare
Sourced in United States

The Discovery VCT PET/CT scanner is a medical imaging system designed to capture detailed images of the body. It combines positron emission tomography (PET) and computed tomography (CT) technologies to provide comprehensive information about the patient's anatomy and metabolic processes.

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6 protocols using discovery vct pet ct scanner

1

Ga-68 Citrate PET/CT and PET/MR Imaging

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Patients were injected with up to 15 mCi (555 MBq; average 7.42 mCi [274.6 MBq], range 3.7–11.9 mCi [136.9–438.5 MBq]) 68Ga-citrate intravenously. PET acquisition was acquired between 120 and 263 min after injection (average 210 min). Images were acquired on either a PET/CT or PET/magnetic resonance (MR). PET/CT examinations were performed on either a Biograph 16 (Hi-Rez) PET/CT scanner (Siemens AG) with an integrated PET and 16-MDCT scanner or a Discovery VCT PET/CT scanner (GE Medical Systems) with an integrated PET and 64-MDCT scanner. A low-dose CT was acquired for PET attenuation correction. PET/MR images were performed on a SIGNA PET/MR (GE Medical Systems). Attenuation correction for PET reconstruction was performed using a MR-based attenuation correction technique provided by the scanner manufacturer.
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2

Dynamic FDG-PET/CT in Idiopathic Pulmonary Fibrosis

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Nine patients, 5 males and 4 females aged 71 ± 6 years, all with diagnosed idiopathic pulmonary fibrosis (IPF), underwent 18F-FDG dynamic PET/CT with the protocol outlined in Table 1 using a GE Discovery VCT PET/CT scanner. All patients were imaged supine immediately post-injection using 209 ± 23 MBq 18F-FDG. The study was split into three stages (early, mid and late) to relieve patient discomfort during the long acquisition. The duration of the cine-CTs acquired for early and mid-cycle stages was set to the duration of the patient’s complete breathing cycle plus one extra second. A cine-CT obtains multiple CT acquisitions over time for each patient slice building up a 4D CT dataset [24 (link)]. The final stage of the study was a normal clinical static PET with a shallow breathing ‘snap shot’ CT study.
The patient data used in this study were the baseline scans (i.e. prior to patient dosing) obtained from a dose escalation study (NCT01725139) of omnipalisib (GSK2126458) in patients with IPF that included FDG-PET as one of the pharmacodynamics endpoints. Institutional Review Board permission, the UK Medicines and Healthcare Products Regulatory Agency (MHRA) approval and informed patient consent were obtained for the study.
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3

Multimodal Imaging for Bone Assessment

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PET/CT data were obtained by a Discovery VCT PET/CT scanner (GE Healthcare). All patients received an injection of 3 MBq NaF per kg body weight after having fasted for 6 h. Image acquisition started approximately 60 min after tracer injection. A diagnostic contrast-enhanced CT scan (64-slice helical, 120 kV, “smart mA” maximum 400 mA) was obtained from the base of the skull to the mid-thigh. The CT slice thickness used in the analysis was 3.75 mm. A PET scan with an acquisition time of 2.5 min per bed position was obtained from the same region.
Whole-body planar bone scans with anterior and posterior views were acquired using a dual head ɣ camera (Skylight or PRISM XP2000, Philips Medical, Surrey) with LEHR collimator, energy window 140 keV ±20%, matrix 256×1024, and scan speed 14 cm/min. All patients received 600 MBq Tc-99m HDP and imaging acquisition was performed 3 h postinjection.
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4

Ga-68 Citrate PET/CT and PET/MR Imaging

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Patients were injected with up to 15 mCi (555 MBq) (average 7.42 mCi [274.6 MBq], range 3.7 to 11.9 mCi [136.9 to 438.5 MBq]) 68Ga-citrate intravenously. PET acquisition was acquired between 120 and 263 minutes after injection (average 210 minutes). Images were acquired on either a PET/CT or PET/MR. PET/CT examinations were performed on either a Biograph 16 (Hi-Rez) PET/CT scanner (Siemens AG, Erlangen, Germany) with an integrated PET and 16-MDCT scanner or a Discovery VCT PET/CT scanner (GE Medical Systems, Milwaukee, WI) with an integrated PET and 64-MDCT scanner. A low-dose CT was acquired for PET attenuation correction. PET/MR images were performed on a SIGNA PET/MR (GE Medical Systems, Milwaukee, WI). Attenuation correction for PET reconstruction was performed using a MR-based attenuation correction (MRAC) technique provided by the scanner manufacturer.
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5

Whole-Body 18F-NaF PET-CT Imaging Protocol

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Whole body volumetric PET-CT images were obtained using either a biograph 16 (high resolution) PET-CT scanner (Siemens Medical Solutions, Knoxville, TN, USA) with an integrated PET and 16-multiple detector computed tomography (MDCT) scanner or a Discovery VCT PET/CT scanner (General Electric Healthcare, Waukesha, WI, USA) with an integrated PET and 64-MDCT scanner. Images were acquired from head to toe approximately 60 min following the intravenous (IV) administration of 160 MBq (4.32 mCi) of 18F-NaF. CT images were used for attenuation correction of PET images.
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6

PET/CT Myocardial Perfusion Imaging Protocol

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Patients were scanned with the Discovery VCT PET/CT scanner (GE Healtchare, US) as previously described in13 (link),17 (link),18 (link). The study protocol included computed tomography coronary angiography (CTA) and myocardial PET perfusion imaging with PET/CT hybrid scanner. An adenosine stress perfusion PET was performed immediately after CT-based attenuation correction. Adenosine was started 2 min before the start of the scan and was infused at 140 μg/kg body weight per minute. 15O-labeled water (900 to 1100 MBq) was injected (Radiowater Generator, Hidex Oy, Finland) as an intravenous bolus over 15 s. A dynamic acquisition of the heart was performed (14 × 5 s, 3 × 10 s, 3 × 20 s, and 4 × 30 s). Images were reconstructed using two-dimensional ordered expectation maximization algorithm (2D-OSEM) using a 35 cm field of view, 128 × 128 matrix size, 2 iterations, 20 subsets and a 6.0 mm Gaussian post-filter.
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