All protocols for animal use and euthanasia were reviewed and approved by the Animal Care Committee of the Joslin Diabetes Center. The experiments were in accordance with National Institutes of Health (NIH) guidelines following the standards established by the Animal Welfare Acts and by the documents entitled ‘Principles for Use of Animals’ and ‘Guide for the Care and Use of Laboratory Animals’. Male Zucker lean (ZL) rats, Zucker fatty (ZF) rats, Zucker diabetic fatty (ZDF) and their control (LEAN +/?) were from Charles River (Wilmington, MA, USA). C57BL/6 mice were from Jackson Laboratory (Bar Harbor, ME, USA). PDGF-BB was purchased from Sigma (St Louis, MO, USA).
Zucker fatty rats
Manufactured by Charles River Laboratories
Sourced in United States
The Zucker fatty (ZF) rat is a genetic model that exhibits obesity, insulin resistance, and other metabolic abnormalities. It is commonly used in research related to metabolic disorders.
Automatically generated - may contain errors
2 protocols using zucker fatty rats
1
Zucker Rat Animal Study Protocol
2
Zucker Rat Diabetes Animal Protocol
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