3 t skyra scanner

Anatomical (1 mm isotropic voxel) and functional (TR = 2 s; TE = 25 ms; FA = 90°; 3 mm isotropic voxel) MRI data were acquired using a Siemens 3 T Skyra scanner (Siemens Medical Systems, Germany) with a 32-channel head coil at the Hoglund Biomedical Imaging Center of the University of Kansas Medical Center. The AFNI package^{50 (link)} was used for preprocessing and statistical analyses of fMRI data. All participants showed less than 3 voxels of head motion (< 9 mm). We applied slice-time correction, motion correction, spike correction (3dDespike), spatial resampling (3 × 3 × 3 mm) and normalization to the standard Talairach template, Gaussian spatial smoothing (FWHM: 6 mm), and intensity normalization (each voxel’s mean was set to 100).

The 5D EP-COSI data was acquired on a Siemens 3 T Skyra scanner (Siemens Healthineer, Erlangen, Germany) with a dedicated “receive” 24-channel phase-array breast coil and a body “transmit” coil (FOV: 160 × 160 × 120mm³, 1.5 mL voxel volume, TR/TE were 1500/35 ms), running on VE11C software platform. 64 t₁ points sampled were used along F₁^{15 (link)} with a spectral bandwidth (SW) of 1250 Hz and 512 complex t₂ points, and a SW of 1190 Hz along F₂. A three-pulse sequence^{27 (link)} was employed before the global water suppression. A non-water suppressed scan with one t₁ point was acquired for eddy current phase correction and coil combination^{28 (link)}. Two spatial and one spectral dimensions (k_y,k_z,t₁) were non-uniformly sampled with an exponentially-weighted sampling density along t₁ and gaussian sampling density along the k_y-k_z plane for an acceleration factor of 8. The total scan time was 28 min and 48 s.