CT imaging examinations were performed using the Philips ICT 256 and the Philips IQon spectral CT. Device parameters are as follows: tube voltage 120 kV or 130kv, with activated automatic tube current modulation, collimation 64 × 0.6 mm (Philips ICT 256) or 64 × 0.625 mm (Philips IQon spectral CT); pitch 0.9; image matrix 512× 512; slice thickness/slice interval 1 mm/1 mm (Philips ICT 256) or 0.683 mm/0.751 mm (Philips IQon spectral CT). Pixel spacing 0.605-0.751mm. The patients were scanned from the hemidiaphragm to the pelvic foor.The patients were injected with 100 mL of iopamidol or 80 mL of ioversol intravenously, followed by a 50 mL saline chaser at a rate of 3 mL/s. Corticomedullary-phase, nephrographic-phase, and excretory-phase images were obtained at 30 s, 60 s, and 300 s after the threshold was achieved in the thoracoabdominal aorta junction, respectively.
Iqon spectral ct
Manufactured by Philips
Sourced in United States, Netherlands, Germany
The IQon Spectral CT is a computed tomography (CT) imaging system developed by Philips. It utilizes spectral imaging technology to capture information about the composition of the scanned object, providing additional data beyond traditional CT imaging. The core function of the IQon Spectral CT is to acquire and analyze spectral data to enhance diagnostic capabilities, but a detailed description cannot be provided while maintaining an unbiased and factual approach.
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Lab products found in correlation
Ict 256, by Philips (7 mentions)
Brilliance 64, by Philips (5 mentions)
Discovery ct750 hd, by GE Healthcare (4 mentions)
Somatom definition, by Siemens (4 mentions)
Somatom definition as, by Siemens (4 mentions)
Somatom definition flash, by Siemens (3 mentions)
Somatom force, by Siemens (3 mentions)
Iodixanol, by GE Healthcare (3 mentions)
Aquilion one, by Canon (3 mentions)
Doseright 3d dom, by Philips (3 mentions)
Care dose 4d, by Siemens (2 mentions)
Doseright system, by Philips (2 mentions)
Omnipaque 300 mgi ml, by Daiichi Sankyo (2 mentions)
Accupaque 350, by GE Healthcare (2 mentions)
Intellispace portal, by Philips (2 mentions)
Iobitridol, by Guerbet (2 mentions)
Intellispace portal vision 10, by Philips (2 mentions)
Brilliance ict 256, by Philips (2 mentions)
Smart ma, by GE Healthcare (1 mentions)
Ge revolution, by GE Healthcare (1 mentions)
101 protocols using iqon spectral ct
1
Contrast-Enhanced CT Imaging Protocol
2
Quantifying Bone Mineral Density from CT Scans
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BMD measurements were performed in patients that received CT in a time period ± 1 month around the MR imaging sessions. CT images were acquired with one dual-layer dual-energy CT scanner (IQon Spectral CT, Philips Healthcare) and one multislice detector CT scanner (iCT 256, Philips Healthcare). CT was performed according to our routine clinical protocols: collimation, 0.6 mm; pixel spacing, 0.4/0.3 mm; pitch factor, 0.8/0.9; tube voltage (peak), 120 kV; modulated tube current, 102–132 mA. Images were reformatted in 3-mm slice thickness using a bone-specific convolution kernel.
For BMD measurements, a mid-line 15mm MPR section in sagittal reformations was created with a PACS tool (IDS7, Sectra). Cylindrical volumes of interest were manually positioned in the non-fractured lumbar vertebrae by one radiologist (G.C.F.), and mean Hounsfield Units (HU) were noted (23 (link)). Fractured or otherwise altered vertebrae (e.g. vertebrae with severe degenerative changes, vertebrae after vertebro-/kyphoplasty) were excluded. The HU values were then converted into BMD using conversion equations as previously described: (i) 0.928 x HU + 4.5 mg/cm3 for the IQon Spectral CT, (ii) 0.855 x HU + 1.172 mg/cm3 for the Philips iCT 256 (24 (link), 25 (link)). Osteoporosis was defined as BMD < 80 mg/cm3 and osteopenia as 80 ≤ BMD ≤ 120 mg/cm3 (26 ).
For BMD measurements, a mid-line 15mm MPR section in sagittal reformations was created with a PACS tool (IDS7, Sectra). Cylindrical volumes of interest were manually positioned in the non-fractured lumbar vertebrae by one radiologist (G.C.F.), and mean Hounsfield Units (HU) were noted (23 (link)). Fractured or otherwise altered vertebrae (e.g. vertebrae with severe degenerative changes, vertebrae after vertebro-/kyphoplasty) were excluded. The HU values were then converted into BMD using conversion equations as previously described: (i) 0.928 x HU + 4.5 mg/cm3 for the IQon Spectral CT, (ii) 0.855 x HU + 1.172 mg/cm3 for the Philips iCT 256 (24 (link), 25 (link)). Osteoporosis was defined as BMD < 80 mg/cm3 and osteopenia as 80 ≤ BMD ≤ 120 mg/cm3 (26 ).
3
Spectral CT Brain Imaging Protocol
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We collected clinical spectral CT images of 22 patients with Philips IQon Spectral CT devices. All exams were performed in Nanjing Gulou Hospital, China, with the approval of the institutional review board and patient consent forms. Philips IQon Spectral CT applies spectral detector technology to implement dual-energy scans. Virtual mono-energetic images at different X-ray energy levels can be reconstructed from the data collected. In our experiments, images at 70 keV, 110 keV, and 150 keV were used to evaluate the proposed method. Noncontrast-enhanced brain virtual mono-energetic images (2463 slices in total) were collected for each energy level and all images were reconstructed using a build-in algorithm provided by the CT vendor. Similar to the Siemens dataset, the Philips dataset was also split into a training set, a validation set and a testing set randomly with 16, 3 and 3 patients included respectively.
4
Multidetector-row CT Imaging for Renal Colic
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All abdomen-pelvis CT examinations for evaluation of renal colic or calculi were performed on one of the three multidetector-row CT (MDCT) scanners: 96-detector-row, third-generation, dual-source MDCT (Siemens Force, Siemens Healthineers, Forchheim, Germany; n = 106 patients), 256-detector-row single-source MDCT (GE Revolution, GE Healthcare, Waukesha, Wis.; n = 83 patients), and 64-detector-row single-source MDCT (Philips IQon Spectral CT, Philips Healthcare, Eindhoven, The Netherlands; n = 13 patients). The following scan parameters were used on all CT scanners: 100–120 kV, automatic exposure control (Smart mA, GE; 3D Modulation, Philips; Care Dose 4D, Siemens), 0.5-s gantry rotation time, and 0.9–1:1 pitch. Reconstructed section thickness was 1–1.25 mm with a 0.8–1 mm overlap and soft tissue reconstruction algorithm using vendor-specific iterative reconstruction techniques (ASIRv, GE; iDose 4, Philips; ADMIRE, Siemens).
5
Multi-Modal CT Imaging Protocol for Thoracic Evaluation
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CT imaging was performed using one of four 64-slice multidetector CT scan machines (Philips Brilliance CT 64; Philips Medical Systems, Eindhoven, Netherlands), Philips IQon spectral CT (Philips Medical Systems, Eindhoven, Netherlands), GE Discovery CT750 HD (GE Medical Systems, Waukesha, USA), and Somatom Definition Flash (Siemens Healthineers, Erlangen, Germany). Detailed acquisition and reconstruction protocol specifications are provided in Supplementary Material 1
6
Multivendor Brain CT Imaging Protocol
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Brain CT was performed on the following scanner models: Canon Aquilion ONE Genesis (Canon Medical Systems, Otawara, Japan), GE Discovery CT750 HD and Revolution CT (GE Healthcare, Milwaukee, WI), Philips IQon Spectral CT (Philips Healthcare, Best, Netherlands) and Siemens SOMATOM Definition Flash (Siemens Healthineers, Erlangen, Germany). Scanning was performed with/without contrast agent in standard doses. Sub-millimeter spatial resolution images were acquired and reconstructed in three planes with 5-millimeter slice thickness.
7
Cardiac Enhancement Imaging and Left Atrial Appendage Measurement
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An IQon-Spectral CT instrument from Philips was used for cardiac enhancement imaging and to display the external morphology of the LAA via 3D reconstruction. In the LAA measurement method, which is similar to conventional RT3D-TEE, the LAA LZ is manually adjusted from three mutually perpendicular planes, and the LZ max, LZ min, LZ area, and LZ cir parameters are measured separately (Figure 2D ).
8
Spectral CT Imaging of Abdomen
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Scans were performed with an SDCT scanner (IQon spectral CT, Philips Healthcare, Amsterdam, The Netherlands). Patients fasted for 4 to 6 hours before undergoing scanning, and the scanning range was from the top of the diaphragm to the lower edge of the ischial tubercle. The scanning parameters were as follows: tube voltage, 120 kV; automatic tube current control modulation technology (151–193 mA); slice thickness, 5 mm; slice spacing, 5 mm; pitch, 1; field of view, 350 mm; and matrix, 512×512. The contrast agent ioversol (350 mg/mL; Jiangsu Hengrui Pharmaceuticals Co., Ltd., Lianyungang, China) was injected intravenously through the elbow with a double-tube high-pressure syringe at a dose of 0.8–1.0 mL/kg and an injection rate of 2.5–3.0 mL/s. After injection of contrast agent, 20 mL of normal saline was injected at a flow rate of 3.5 mL/s. Scanning was initiated using the contrast agent autotracking trigger technique. The trigger point of the scan was located in the abdominal aortic cavity. The trigger threshold of the arterial phase (AP) was 150 HU, and the venous phase (VP) was scanned 35 seconds after AP.
9
Contrast-Enhanced Neck CT Imaging
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All patients in our study underwent preoperative contrastenhanced neck scans through 64-slice DLCT devices (IQon Spectral CT, Philips Healthcare). The DLCT scanning protocol was as follows: tube voltage, 120 kVp; tube current, modulated with automated exposure control (DoseRight system, Philips Healthcare); detector collimation, 64 × 0.625 mm; field of view, 350 mm; matrix, 512 × 512; layer thickness, 3 mm; reconstruction thickness, 0.67 mm. Patients were intravenously injected with nonionic contrast media (Iopamidol 350 mg/ml, Bracco) at a dose of 1.5 ml/kg and an injection rate of 3.5 ml/s, followed by 30 ml of saline flashing at the same rate. The arterial phase (AP) scan was performed with a delay of 6 seconds and a venous phase (VP) scan was performed with a delay of 50 seconds after the CT value of the descending aorta lumen at the tracheal bifurcation level reached 150 Hounsfield units, respectively.
10
Dual-Phase Spectral CT Imaging
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All patients underwent abdominal spectral CT scanning (IQon Spectral CT, Philips Healthcare, Best, the Netherlands) with an unenhanced and dual-phase enhanced scan. The main parameters were tube voltage of 120 kVp, automatic tube current modulation, collimation of 64 × 0.625 mm, pitch value of 0.99, X-ray tube rotation speed of 0.75 s, and the reconstruction slice thickness of 1.0 mm. A contrast enhancement scan was performed with a fully automatic high-pressure syringe by injecting 80 mL of iodixanol (320 mgI/mL) through the elbow vein at a rate of 3.0 mL/s. The scan was triggered at the level of the coeliac trunk of the abdominal aorta in the arterial phase with a threshold of 150 HU. The scan was delayed by 70 s in the venous phase. Both conventional images and spectral-based images (SBI) data were reconstructed.
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