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Automatic hematology analyzer

Manufactured by Beckman Coulter
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Sourced in China, United States

The Automatic hematology analyzer is a laboratory instrument used to perform a complete blood count (CBC) analysis. It automatically measures and analyzes various blood cell parameters, including red blood cells, white blood cells, and platelets.

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Lab products found in correlation

Ficoll paque plus, by GE Healthcare (1 mentions)

Close spelling variants of this product

Hematology analyzer Automatic analyzer

4 protocols using automatic hematology analyzer

1

Hepatotoxicity Evaluation through Biomarkers

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The contents of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in the serum were detected using an automatic hematology analyzer (Beckman Coulter, Inc.) to evaluate the hepatotoxicity. The contents of antioxidant index superoxide dismutase (SOD) and glutathione (GSH) and oxidative damage index malondialdehyde (MDA) in the liver homogenate were tested using assay kits (Nanjing Jiancheng Bioengineering Institute, China). All operations are carried out in accordance with the instructions strictly.
Han T., Zhang H., Xu W., Li C., Wang M., Bai Y., Yang L., Zhang S., Jia Z., Xu X., Zhao C., Wei F, & Li X. (2021). Study on the Mechanism of Reducing Hepatotoxicity of Water-Grinding Realgar by Metabolomics, Morphology, and Chemical Analysis. Evidence-based Complementary and Alternative Medicine : eCAM, 2021, 8538287.
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2

Leukocyte Isolation from Mouse Blood

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Whole blood (heparin as anticoagulant, 10 U/mL) were taken from mouse heart, and then leukocytes were isolated using Ficoll-Paque Plus (GE Healthcare). The distributions of circulating leukocytes were counted by automatic hematology analyzer (Beckman Coulter).
Niu H., Li Y., Li H., Chi Y., Zhuang M., Zhang T., Liu M, & Nie L. (2016). Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity. Scientific Reports, 6, 20171.
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3

Automated Eosinophil Quantification

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The automatic hematology analyzer purchased from Beckman Coulter Commercial Enterprise (China) Co., Ltd. (article no. N/A) was used to detect the eosinophil granulocyte.
Wei H., Li W., Jiang Z., Xi X, & Qi G. (2019). Clinical efficacy of montelukast sodium combined with budesonide or combined with loratadine in treating children with cough variant asthma and influence on inflammatory factors in the serum. Experimental and Therapeutic Medicine, 18(1), 411-417.
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4

Identification of Hemoglobin and Blood Disorders

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HbE, α- and β-thalassemia traits were identified using cation exchange high performance liquid chromatography, using methods described elsewhere [14 ,15 (link)]. The α-thalassemia trait was confirmed by multiplex gap polymerase chain reaction [16 (link),17 (link)], and glucose-6-phosphate dehydrogenase (G6PD) deficiency by fluorescent spot test [18 (link)]. Complete blood cell count was performed by automatic hematology analyzer (Beckman Coulter, CA, USA).
Lithanatudom P., Wipasa J., Inti P., Chawansuntati K., Svasti S., Fucharoen S., Kangwanpong D, & Kampuansai J. (2016). Hemoglobin E Prevalence among Ethnic Groups Residing in Malaria-Endemic Areas of Northern Thailand and Its Lack of Association with Plasmodium falciparum Invasion In Vitro. PLoS ONE, 11(1), e0148079.
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