CYP26A1 and CYP26B1 were generous gifts from Dr. Nina Isoherranen (University of Washington). Recombinant CYP2C8 Supersomes® and purified human cytochrome P450 reductase were obtained from Corning Life Sciences (Tewksbury, MA). Tazarotenic acid, MM11253, liarazole, EC23, AM80 and candesartan were purchased from Tocris Chemicals (Bristol, United Kingdom). Montelukast, pioglitazone, rosiglitazone and zafirlukast were from Cayman Chemical (Ann Arbor, MI). Talarazole was purchased from MedChem Express (Monmouth Junction, NJ). Rapid equilibrium dialysis (RED) device kits were obtained from ThermoFisher Scientific (Waltham, MA). All other chemicals were from Sigma-Aldrich (St. Louis, MO) and were of the highest grade available.
Zafirlukast
Manufactured by Cayman Chemical
Sourced in United States
Zafirlukast is a chemical compound used as a laboratory reagent. It functions as a leukotriene receptor antagonist.
Automatically generated - may contain errors
Lab products found in correlation
Montelukast, by Cayman Chemical (3 mentions)
Rosiglitazone, by Cayman Chemical (2 mentions)
Pioglitazone, by Cayman Chemical (2 mentions)
Steponeplus thermocycler, by Thermo Fisher Scientific (1 mentions)
Penicillin streptomycin, by Thermo Fisher Scientific (1 mentions)
Sodium pyruvate, by Thermo Fisher Scientific (1 mentions)
Phosphate buffered saline (pbs), by Thermo Fisher Scientific (1 mentions)
Dulbecco modified eagle medium (dmem), by Thermo Fisher Scientific (1 mentions)
Opti mem, by Thermo Fisher Scientific (1 mentions)
Dexamethasone (dex), by Merck Group (1 mentions)
Insulin, by Merck Group (1 mentions)
Sodium dodecyl sulfate (sds), by AppliChem (1 mentions)
Fetal calf serum (fcs), by Capricorn (1 mentions)
Triton x 100, by AppliChem (1 mentions)
Sodium chloride (nacl), by AppliChem (1 mentions)
Newborn calf serum, by Harvard Bioscience (1 mentions)
Oil red o, by Merck Group (1 mentions)
14 15 eet d11, by Cayman Chemical (1 mentions)
3 isobutyl 1 methyl xanthine (ibmx), by Cayman Chemical (1 mentions)
Np 40, by AppliChem (1 mentions)
3 protocols using zafirlukast
1
CYP26A1 and CYP26B1 Enzyme Assay
2
3T3-L1 Cell Differentiation Assay
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DMEM, OptiMEM, penicillin-streptomycin, PBS and sodium pyruvate were obtained from Gibco by Life Technologies (Carlsbad, CA, United States), SYBR green MicroAmp Fast Optical 96-well Reaction Plate 0.1 ml and StepOnePlus thermocycler were obtained from Applied Biosystems (Foster City, CA, United States). FCS was purchased from Capricorn (Ebsdorfergrund, Germany). New born calf serum was purchased from Biochrom (Berlin, Germany). All primer pairs were purchased from Eurofins (Friedrichsdorf, Germany). Cell culture flasks (T75, Cell+, vented cap) and 6-well plates for sub-culturing 3T3-L1 cells were obtained from SARSTEDT (Nümbrecht, Germany). Rosiglitazone, pioglitazone, zafirlukast, montelukast, IBMX and (±)14(15)-EET-d11 were purchased from Cayman Chemical (Ann Arbor, MI, United States). Insulin, dexamethasone and Oil Red O were obtained from Sigma Aldrich (St. Louis, Missouri, MO, United States). Tris, Triton-X-100, NP-40, NaCl, EDTA and SDS were purchased from AppliChem (Darmstadt, Germany).
3
Diverse Pharmacological Modulators of Inflammatory Pathways
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Montelukast, pranlukast and zafirlukast as leukotriene receptor antagonists were purchased from Cayman Chemical (Ann Arbor, MI, USA). Suplatast tosilate as a Th2 cytokine inhibitor, sodium cromoglicate, tranilast, amlexanox and pemirolast as mediator release inhibitors, ozagrel as a thromboxane A2 synthesis inhibitor, seratrodast as a thromboxane A 2 receptor antagonist, diphenhydramine as an ethanolamine H1 blocker, chlorpheniramine as a propylamine H1 blocker, cyproheptadine as a piperidine H1 blocker, promethazine as a phenothiazine H1 blocker, and ketotifen, fexofenadine, epinastine, cetirizine, levocetirizine, emedastine, loratadine, azelastine, mequitazine and ebastine as second-generation H1 receptor antagonists were purchased from Tokyo Chemical Industry (Tokyo, Japan).
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