Carbopol 934p

Manufactured by Merck Group

Sourced in United States

Carbopol 934P is a high-molecular-weight, crosslinked, polyacrylic acid polymer that is commonly used as a gelling agent, thickener, and suspending agent in various pharmaceutical and cosmetic formulations. It is a white, fluffy powder that swells in water to form a clear, acidic, and viscous gel.

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Lab products found in correlation

5 protocols using carbopol 934p

Formulation and Evaluation of Skin Cream

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SIM was kindly gifted to us by Biocon Pvt. Ltd. QRC and poloxamer 188 were procured from Acros organics, Morris Plains, New Jersey, USA. Poloxamer 407, Carbopol 934 P and chitosan were purchased from Sigma-Aldrich, St. Louis, MO, USA. The National Centre for Cell Sciences (NCCS), India, gifted the HCS-3 cell lines topus. All additional chemicals, reagents, and solvents used were of analytical grade.

Kurakula M, & Naveen N.R. (2020). In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma. Marine Drugs, 18(4), 201.

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Herbal Formulation Development and Analysis

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HPMC K4, Carbopol 934P, HPMC K15, NaHCO₃, Mg stearate and citric acid were purchased from Sigma Aldrich, Germany. The silymarin standard was gifted by Nutrabiotics, Peshawar. Methanol and Acetonitrile HPLC grade were purchased from Fisher, UK.

Ahmad S., Khan J.A., Kausar T.N., Mahnashi M.H., Alasiri A., Alqahtani A.A., Alqahtani T.S., Walbi I.A., Alshehri O.M., Elnoubi O.A., Mahmood F, & Sadiq A. (2023). Preparation, Characterization and Evaluation of Flavonolignan Silymarin Effervescent Floating Matrix Tablets for Enhanced Oral Bioavailability. Molecules, 28(6), 2606.

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Transdermal Delivery of Hesperidin

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Hesperidin was purchased from Sigma-Aldrich (St. Louis, MO, USA). Phospholipid 90G was procured from Lipoid, Germany. Carbopol 934P, Polyethylene glycol, and Triethanolamine were procured from Sigma-Aldrich (St. Louis, MO, USA). Rhodamine B, Ascorbic acid, 1,1diphenyl-1-picrylhydrazy (DPPH) were procured from SD Fine Chemicals, Mumbai, India. Rodent rat skin was utilized from Etsy Pvt Ltd. India. All the other reagents and chemicals used in the experiments were of analytical grade.

Alam P., Imran M., Jahan S., Akhtar A, & Hasan Z. (2023). Formulation and Characterization of Hesperidin-Loaded Transethosomal Gel for Dermal Delivery to Enhance Antibacterial Activity: Comprehension of In Vitro, Ex Vivo, and Dermatokinetic Analysis. Gels, 9(10), 791.

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Biopolymer-Based Insulin Delivery System

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Chitosan (Average Mw 100 KDa, 75–85% deacetylated), Carbopol 934P (viscosity 800–11,000 cP), hydroxypropyl m ethylcellulose (viscosity 2600–5600 cP), and ethylcellulose (viscosity 10 cP) were purchased from Sigma-Aldrich. (Oakville, Ontario, Canada). Sodium tripolyphosphate (TPP) and sodium alginate (low viscosity) was purchased from VWR (Radnor, Pennsylvania, USA). Recombinant human insulin was obtained from Fisher Scientific (Waltham, Massachusetts, USA). Fluorescein isothiocyanate (FITC)-labelled human insulin and the 4′,6-Diamidino-2-phenylindole dihydrochloride (DAPI) were obtained from Sigma-Aldrich. (Oakville, Ontario, Canada). The HepG2 and Caco-2 cell line was obtained from ATCC (Manassas, Virginia, USA) while TR-146 Cell line was purchased from Sigma-Aldrich. (Oakville, Ontario, Canada). Other reagents were of analytical or chromatography grade.

Pratap-Singh A., Guo Y., Baldelli A, & Singh A. (2023). Mercaptonicotinic acid activated thiolated chitosan (MNA-TG-chitosan) to enable peptide oral delivery by opening cell tight junctions and enhancing transepithelial transport. Scientific Reports, 13, 17343.

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Butenafine Hydrochloride Formulation Development

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Butenafine Hydrochloride (BTF) was obtained as a gift sample from Jazeera Pharmaceutical Industries (JPI), Riyadh. Ethyl cellulose, Polyvinyl Alcoho (PVA, Mole wt- 85,000–124,000), Dichloromethane and Carbopol 934P were purchased from “Sigma-Aldrich (St. Louis, Missouri, USA)”. All other reagents and chemicals utilized were of analytical grades. Deionized water (18.2 MΩ·cm at 25 °C) were collected from Millipore Mill-Q Gradient A-10 water-purification systems (Bedford, MA, United States).

Ahmed M.M., Fatima F., Anwer M.K., Ibnouf E.O., Kalam M.A., Alshamsan A., Aldawsari M.F., Alalaiwe A, & Ansari M.J. (2021). Formulation and in vitro evaluation of topical nanosponge-based gel containing butenafine for the treatment of fungal skin infection. Saudi Pharmaceutical Journal : SPJ, 29(5), 467-477.

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