S100 protein clone 4c4.9

Manufactured by Roche

Sourced in United States

The S100 protein (clone 4C4.9) is a laboratory reagent used for the detection and quantification of the S100 protein. The S100 protein is a calcium-binding protein that plays a role in various cellular processes. The clone 4C4.9 is a monoclonal antibody that specifically recognizes the S100 protein.

Automatically generated - may contain errors

Lab products found in correlation

Chromogranin clone lk2h10, by Roche (1 mentions) Muscle specific actin clone hhf35, by Roche (1 mentions) Desmin clone d33, by Agilent Technologies (1 mentions) Benchmark xt autostainer, by Roche (1 mentions) Ventana benchmark ultra autostainer, by Roche (1 mentions)

2 protocols using s100 protein clone 4c4.9

Comprehensive Immunohistochemistry Panel for Sinonasal Tumors

Check if the same lab product or an alternative is used in the 5 most similar protocols

Immunohistochemistry for CD99 (clone 12E7; Leica, Buffalo Grove, IL; prediluted), pancytokeratin (PCK26; Ventana, Tuscon, AZ; prediluted); p40 (Ab-1; Oncogene Research Products, Cambridge, MA; 1:2000 dilution), synaptophysin (clone 27G12; Leica Microsystems; prediluted); chromogranin (clone LK2H10; Ventana; prediluted); S100 protein (clone 4C4.9; Ventana; prediluted), muscle specific actin (clone HHF35; Ventana, prediluted); desmin (clone D33, Dako, Carpinteria, CA; 1:100 dilution), NUT-1 (clone C52B1, Cell Signaling Technologies, Inc., Danvers, MA, 1:50 dilution), and p16 (clone INK4a; MTM Laboratories, Heidelberg, Germany); was performed on five-micron sections utilizing standard protocols on a Ventana Benchmark XT autostainer. In addition, in situ hybridization for high-risk types of human papillomavirus was also performed utilizing the Ventana HR HPV III probe set that captures HPV genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 66. The sinonasal tissue microarray was also stained with CD99.

Bishop J.A., Alaggio R., Zhang L., Seethala R.R, & Antonescu C.R. (2015). Adamantinoma-like Ewing Family Tumors of the Head and Neck: A Pitfall in the Differential Diagnosis of Basaloid and Myoepithelial Carcinomas. The American journal of surgical pathology, 39(9), 1267-1274.

+ Open protocol

+ Expand

Immunohistochemistry for Rosai-Dorfman Disease

Check if the same lab product or an alternative is used in the 5 most similar protocols

Immunohistochemistry was performed using mouse monoclonal antibodies for S100 protein (clone 4C4.9; prediluted; Ventana Medical Systems, Tucson, AZ, USA) in all 27 cases with histological features of RDD from the prospective and retrospective cohort as well as 11 other cases with prominent histiocytes from the retrospective cohort. Stains for CD1a (clone MS/220; 1:50 dilution; Leica Biosystems, Buffalo Grove, IL, USA), CD207 (Langerin; clone 12D6; 1:200 dilution; LSBio, Seattle, WA, USA) and cyclin D1 (clone SP4; prediluted; CellMarque/Sigma‐Aldrich, St Louis, MO, USA) were also performed on most cases with histological features of RDD based on tissue availability. Staining was performed using Ventana BenchMark Ultra autostainers (Ventana Medical Systems), and signals were visualised using ultraView polymer detection kits (Ventana Medical Systems).

Rooper L.M., White M.J., Duffield A.S., Gagan J., London NR J.r., Montgomery E.A, & Bishop J.A. (2022). Limited sinonasal Rosai–Dorfman disease presenting as chronic sinusitis. Histopathology, 81(1), 99-107.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!