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Marathon

Manufactured by Medtronic
Sourced in United States

The Marathon is a versatile laboratory equipment used for centrifugation. It is designed to separate components of a liquid sample based on their density and size. The Marathon can be used for various applications in research and clinical settings.

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4 protocols using marathon

1

Embolization of Cerebrovascular Lesions

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Using a transfemoral approach, a 6F or 7F guiding catheter was placed into the internal carotid or vertebral artery. Intravenous heparin was intermittently administered throughout the procedure, and serial activated clotting time (ACT) measurements were taken throughout the procedure to maintain the ACT above 200 seconds. A microcatheter (Marathon; Medtronic, Minneapolis, MN, USA) was advanced to the target vessel. To avoid ischemic complications, in the case of feeders projecting from the AChA, the catheter tip was advanced beyond the angiographic plexal point [10 (link)] and a provocative test was performed using lidocaine and a barbiturate agent under the local anesthesia. In the case of feeders projecting from the PChA, the catheter tip was advanced just proximal to the tumor. Embolization was performed using 100–300 µm trisacryl gelatin microspheres (Embosphere; Merit Medical Systems, Inc. UT, USA) and/or a variety of detachable coils.
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2

Cavernous Sinus Fistula Embolization

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The right femoral artery was punctured, a 5/6F artery sheath was implanted, and the proper blood-supplying artery was chosen based on the diameter, length, tortuosity, and type of collateral branch determined using super-selective angiography. An Echelon™-10 or Marathon™ microcatheter (Medtronic, USA) was used to super-selectively approach the cavernous sinus fistula with the aid of the microguidewire, and the angioarchitecture was revealed through super-selective angiography, thus avoiding dangerous anastomoses. Spring coil embolization was performed on the fistula to slow down the blood flow, when necessary. Subsequently, Onyx™ LES (Medtronic, USA) was slowly injected using the roadmap-bolus-diffusion-pause-roadmap-bolus method. Angiography was repetitively conducted during the Onyx injection to observe the status of the cavernous sinus embolization. The surgery was terminated once the fistula disappeared.
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3

Endovascular Management of Arteriovenous Malformations

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Procedures were performed under either general anaesthesia or local anaesthesia, depending on patient condition. Access to the femoral artery was established using a 5 French or 6 French sheath. The nidus of the AVM was identified through selective angiography of the internal carotid artery (ICA) and external carotid artery (ECA). For endovascular access, a microcatheter (Rebar 18; Medtronic, Minneapolis, MN, USA) was advanced towards the nidus through the ECA. In case of vascular tortuosity, other microcatheters were used (SL10; Stryker, Kalamazoo, MI, USA or Marathon; Medtronic, Minneapolis, MN, USA) were used.
For endovascular particulate embolization, particles (Contour; Boston Scientific Corporation, Marlborough, MA, USA) were applied. For endovascular liquid embolization we used two agents (Onyx; ev3 Neurovascular, Irvine, CA, USA and Glubran 2; GEM SRL, Viareggio, Italy. For percutaneous interstitial embolization (sclerotherapy), Bleomycin mixed with contrast medium (50:50) was applied using 26–30 Gauge needles under fluoroscopic guidance.
Post-treatment, catheter angiography and MR angiography were performed to confirm successful elimination of the AVM nidus.
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4

Embolization of Cranial Dural Arteriovenous Fistulas

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For cranial DAVFs with MMA as the feeding artery, digital subtraction angiography (DSA) was performed to assess the angioarchitecture of the DAVF, and the feeding artery, fistula size, draining vein, location, Cognard grade, and other parameters were recorded. When performing EVT, a Marathon or Apollo microcatheter (Medtronic, Irvine, California, USA) was used to approach the DAVF as closely as possible, and Onyx (Medtronic, Irvine, California, USA) was injected to cast the DAVF as much as possible in order to penetrate the draining vein. The EVT procedure was monitored simultaneously using angiography of another artery when necessary. If the DAVF could not be seen via the MMA and other feeding arteries, complete embolization was achieved or the EVT was incomplete.
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