Lc ms grade water and acetonitrile acn

Manufactured by Thermo Fisher Scientific

Sourced in United States

LC-MS-grade water and acetonitrile (ACN) are high-purity solvents specifically designed for use in liquid chromatography-mass spectrometry (LC-MS) applications. These solvents are produced and tested to meet the stringent requirements for LC-MS analysis, ensuring low levels of impurities and contaminants that could interfere with the analytical process.

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Lab products found in correlation

Hplc grade hexane, by Thermo Fisher Scientific (2 mentions) Hplc grade acetone, by Merck Group (2 mentions) Acetone, by Thermo Fisher Scientific (2 mentions) Dichloromethane, by Merck Group (2 mentions) 2 4 dinitrophenylhydrazine, by Merck Group (2 mentions) Ammonium acetate, by Honeywell (2 mentions) Acs grade hydrochloric acid hcl, by Thermo Fisher Scientific (2 mentions) Silica gel 60 thin layer chromatography plates aluminum sheets, by Merck Group (2 mentions) Whatman, by Cytiva (2 mentions) 2 2 dipyridyl disulfide dpds, by MP Biomedicals (1 mentions) Ammonium formate, by Merck Group (1 mentions)

Close spelling variants of this product

Acetonitrile (2707 citations) Acetonitrile (ACN) (189 citations) LC-MS grade (75 citations) MS-grade acetonitrile (58 citations) LC-MS grade acetonitrile (ACN) (31 citations) MS-grade water (25 citations) LC-MS grade acetonitrile and water (10 citations) LC-MS water (9 citations) LC grade acetonitrile (7 citations) Water and acetonitrile (7 citations)

4 protocols using lc ms grade water and acetonitrile acn

Carbonyl Compound Analysis by HPLC-DNPH

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2,4-dinitrophenylhydrazine (DNPH), high performance liquid chromatography (HPLC)-grade acetone, dichloromethane, methanol (MeOH), and water were purchased from Sigma-Aldrich (St. Louis, MO). HPLC-grade hexane, acetone, and ACS-grade hydrochloric acid (HCl) were purchased from Fisher Scientific (Fair Lawn, NJ). Silica gel 60 thin layer chromatography plates (aluminum sheets, 20 × 20 cm, 200 μm) were purchased from EMD Millipore (Billerica, MA). Nylon membrane syringe filters (0.45 μm) were purchased from Whatman Ltd. (Maidstone, Kent, England). LC-MS-grade water and acetonitrile (ACN) were purchased from Thermo Fisher Scientific (Houston, TX) and ammonium acetate from Honeywell Riedel-de Haen (Seelze, Germany).

Fiecke C., Kurzer M., Chen C, & Csallany A.S. (2019). The in Vivo Antioxidant Effects of (−)-Epigallocatechin-3-Gallate Consumption in Healthy Postmenopausal Women Measured by Urinary Excretion of Secondary Lipid Peroxidation Products. Food and nutrition sciences, 10(1), 15-27.

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Carbonyl Compound Analysis by HPLC-DNPH

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Metabolite Identification by Derivatization

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The following chemicals were used: LC‐MS‐grade water and acetonitrile (ACN) (Fisher Scientific, Houston, TX); 2‐hydrazinoquinoline (HQ) and triphenylphosphine (TPP) (Alfa Aesar, Ward Hill, MA); 2,2′‐dipyridyl disulfide (DPDS) (MP Biomedicals, Santa Ana, CA); and dansyl chloride (DC) and n‐butanol (Sigma‐Aldrich, St. Louis, MO). The metabolite standards used for structural confirmation were from Sigma‐Aldrich, Fisher Scientific, Alfa Aesar, Ark Pharm (Libertyville, IL), Frontier Scientific (Logan, UT), and Steraloids (Newport, RI), respectively.

Wang L., Urriola P.E., Luo Z., Rambo Z.J., Wilson M.E., Torrison J.L., Shurson G.C, & Chen C. (2016). Metabolomics revealed diurnal heat stress and zinc supplementation‐induced changes in amino acid, lipid, and microbial metabolism. Physiological Reports, 4(1), e12676.

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Rat Serum LC-MS Lipidomics

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Chemicals used to prepare mobile phases and solutions included LC-MS grade water and acetonitrile (ACN) (Fisher Scientific International, Inc., Pittsburg, PA, USA), isopropyl alcohol (IPA) (Honeywell International, Inc., Charlotte, NC, USA), formic acid (purity > 99.5%) (CovaChem, LLC., Loves Park, IL, USA), and ammonium formate (purity > 99.995%) (Sigma-Aldrich, Inc., St. Louis, MO, USA). Uninjured Sprague Dawley rat serum (ab7488, Abcam, PLC., Cambridge, UK) was used as a reference during LC-MS data collection and to supplement MS/MS data collection. SPLASH II Lipidomix (Sigma-Aldrich, Inc., St. Louis, MO, USA) was used as an analytical internal standard for MS experiments.

Gier E.C., Pulliam A.N., Gaul D.A., Moore S.G., LaPlaca M.C, & Fernández F.M. (2022). Lipidome Alterations following Mild Traumatic Brain Injury in the Rat. Metabolites, 12(2), 150.

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