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Nicotinic acid

Sourced in China

Nicotinic acid is a chemical compound used in various laboratory applications. It is an essential nutrient and a precursor to the coenzyme nicotinamide adenine dinucleotide (NAD), which plays a critical role in cellular metabolism and energy production. As a laboratory reagent, nicotinic acid is commonly used in biochemical assays, cell culture media, and as a precursor for the synthesis of other compounds.

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2 protocols using nicotinic acid

1

Antioxidant and Cytotoxicity Evaluation

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Phloretin (Phl, purity ≥ 98%), isoniazid (Inz, purity = 98%), 2-picolinic acid (99%), theophylline (99%), 4-aminobenzamide (98%), proline (99%), nicotinic acid (99%) and 4-picolinic acid (99%) were purchased from Shanghai Macklin Biochemical Co., Ltd (Shanghai, China). Phloretin (HPLC ≥ 98%) and maleic (99%) acid were purchased from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China). 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) was purchased from Sigma Life Science (St. Louis, MO, USA). 1,1-Diphenyl-2-picrylhydrazyl (DPPH) was purchased from Shanghai Macklin Biochemical Co., Ltd. (Shanghai, China). Methanol was obtained from Guangzhou Reagent Co., Ltd. (Guangzhou, China). The A549 cell line and HepG2 cell line were purchased from the Institute of Biochemistry and Cell Biology Sciences, Chinese Academy of Sciences (Shanghai, China).
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2

Synthesis of Chitooligosaccharide Lactate

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Chitooligosaccharide lactate (deacetylation degree of 94%, molecular weight ≤ 3000 Da) was obtained from Weikang Biomedical Technology Co., Ltd. (Linyi, China). Dimethyl sulfoxide (DMSO), acetonitrile, acetone, absolute ethanol, ethyl acetate, trimethylamine (33% ethanol solution) and triethylamine were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Nicotinic acid, N,N′-carbonyl diimidazole (CDI) and 1,3-dibromopropane were obtained from Macklin Biochemical Co., Ltd. (Shanghai, China). Tripropylamine and tributylamine were purchased from Aladdin Reagent Co., Ltd. (Shanghai, China). All drugs and reagents were obtained from commercial sources and used without further processing.
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