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Pravastatin sodium

Manufactured by Merck Group
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Pravastatin sodium is a laboratory product manufactured by Merck Group. It is a chemical compound used in various research and analytical applications. The core function of pravastatin sodium is to serve as a reference standard or analytical reagent in scientific investigations and experiments.

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Lab products found in correlation

4 6 diamidino 2 phenylindole (dapi), by Wuhan Servicebio Technology (1 mentions) Anti mouse cd16 32 clone 2.4g2, by BD (1 mentions) Atorvastatin calcium, by Merck Group (1 mentions) Valsartan, by Merck Group (1 mentions)

Spelling variants of this product

Pravastatin (56 citations) Pravastatin sodium salt hydrate (5 citations)

3 protocols using pravastatin sodium

1

Hypercholesterolemic Mouse Model Study

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Six weeks old nude mice (BALB/cA) (Beijing HFK Bioscience CO., LTD) were separately treated in a group of 10 by either normal diet (Beijing HFK Bioscience CO., LTD), high cholesterol diet (HCD) containing 2% cholesterol and 0.25% sodium cholate) (Beijing HFK Bioscience CO., LTD) or normal diet containing pravastatin sodium (40mg kg−1 day−1,Sigma). Experiments were performed using these mice.
Zheng S., Lin J., Pang Z., Zhang H., Wang Y., Ma L., Zhang H., Zhang X., Chen M., Zhang X., Zhao C., Qi J., Cao L., Wang M., He X, & Sheng R. (2022). Aberrant Cholesterol Metabolism and Wnt/β‐Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth. Advanced Science, 9(28), 2200750.
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2

Murine Immune Cell Profiling Protocol

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Pravastatin sodium was purchased from Sigma-Aldrich (St. Louis, MO, USA). BV421-conjugated anti-mouse Ly6C (clone AL-21), PE-conjugated anti-mouse CD11b (clone M1/70), APC-conjugated anti-mouse Ly6G (clone 1A8), BV605-conjugated anti-mouse CD115 (clone T38-320), and anti-mouse CD16/32 (clone 2.4G2) were purchased from BD Pharmingen (Franklin Lakes, NJ, USA). Monoclonal antibodies against mouse F4/80 were obtained from Abcam (Cambridge, UK). Mounting medium with DAPI, hematoxylin–eosin (H&E) and Masson’s trichrome staining reagents were purchased from Wuhan Servicebio Technology (Wuhan, China). Oil Red O (ORO) was obtained from Sangon Biotech (Shanghai, China).
Chen Y., Zhang H., Hu L., Shi H., Liu X., Jia J., Sun S., Ou Y., Luo X., Zhou G, & Shen W. (2020). Pravastatin attenuates atherosclerosis after myocardial infarction by inhibiting inflammatory Ly6Chigh monocytosis in apolipoprotein E knockout mice. The Journal of International Medical Research, 48(7), 0300060520932816.
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3

Validated HPLC Assays for Statins

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USP reference standards used were: valsartan (Sigma-Aldrich, USA), fluvastatin sodium (USP Convention, Rockville, MD, USA), pravastatin sodium (Sigma-Aldrich), atorvastatin calcium (Sigma-Aldrich).
Reagents and methanol of analytical grade quality were used.
Stolarczyk M., Apola A., Maślanka A., Kwiecień A, & Opoka W. (2017). Spectrophotometric method for simultaneous determination of valsartan and substances from the group of statins in binary mixtures. Acta pharmaceutica (Zagreb, Croatia), 67(4).
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