Chelex 100 ion exchange resin

Manufactured by Merck Group

Sourced in United States

Chelex-100 is an ion exchange resin manufactured by Merck Group. It is a styrene-divinylbenzene copolymer containing paired iminodiacetate ions, which function as a chelating group. Chelex-100 can be used to selectively remove metal ions from aqueous solutions.

Automatically generated - may contain errors

Lab products found in correlation

Deferoxamine, by Merck Group (1 mentions)

Close spelling variants of this product

Chelex 100 (100 citations) Chelex 100 resin (58 citations) Chelex (25 citations) Chelex resin (20 citations) Ion exchange resin (2 citations)

2 protocols using chelex 100 ion exchange resin

Radiolabeling of Zirconium-89 Chloride

Check if the same lab product or an alternative is used in the 5 most similar protocols

[⁸⁹Zr]ZrCl₄ in 5 M HCl (20–30 mCi/mL) was purchased from Cyclotron Ltd. (Obninsk, Russia).
Only deionized water 18.2 MΩ·cm (Milli-Q Millipore or TKA Smart2Pure) was used. All chemicals and solvents were of high-purity or pharmaceutical grade (Sigma-Aldrich, Darmstadt, Germany) or Panreac (Barcelona, Spain). Chelex-100 ion exchange resin was purchased from Sigma-Aldrich. ZR-Resin was provided by TrisKem International (Bruz, France). Chromafix 30PS-HCO₃ cartridges were purchased from Macherey-Nagel (Düren, Germany). Deferoxamine was purchased from Sigma-Aldrich (Darmstadt, Germany).

Larenkov A., Bubenschikov V., Makichyan A., Zhukova M., Krasnoperova A, & Kodina G. (2019). Preparation of Zirconium-89 Solutions for Radiopharmaceutical Purposes: Interrelation Between Formulation, Radiochemical Purity, Stability and Biodistribution. Molecules, 24(8), 1534.

+ Open protocol

+ Expand

High-Throughput Drug Screening in Engineered Cells

Check if the same lab product or an alternative is used in the 5 most similar protocols

Four hours after transfection, HEK293T-spCas9 cells were trypsinized and passed into 96-well plates and treated with the drug library in a final concentration of 10 mmol/L for 48 hours. Genomic DNA extraction was performed by using Chelex-100 ion exchange resin (Sigma, St. Louis, MO, USA) for real-time PCR analysis as previously described (11) . The quality of the screening was evaluated by Z' factor, defined as 1
where s cþ and s cÀ are the standard deviations of the values of the NU7441 and DMSO-treated samples, and m cþ and m cÀ are the means of the values of the NU7441 and DMSO-treated samples.

Du J., Chen F., Yu J., Jiang L, & Zhou M. (2021). The PI3K/mTOR Inhibitor Ompalisib Suppresses Nonhomologous End Joining and Sensitizes Cancer Cells to Radio- and Chemotherapy. Molecular cancer research : MCR, 19(11).

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!