MRI data were acquired using a Bruker PharmaScan 7T/16 cm system controlled by Paravision 5.1 software (Bruker BioSpin) with a gradient coil insert (internal diameter = 90 mm, 300 mT/m) and a 4-channel phased-array surface receive coil used for rat brain imaging. Two different tracers were used for this experiment: Gd-DTPA (Magnevist, 21 mM; MW, 938 Da; Bayer HealthCare Pharmaceuticals Inc.) and H217O (90% 17O-enriched water, NUKEM Isotopes). Furthermore, aCSF was used as a negative control. The scanning protocol for all studies consisted of 3 baseline scans, followed by the intrathecal infusion of tracer via the CM catheter (50 μL at 1.8 μL/min; total time, 28 min). MRI data were continually acquired over a period of 85 minutes.
Pharmascan 7t 16 cm system
Manufactured by Bruker
Sourced in Germany
The PharmaScan 7T/16 cm system is a high-field magnetic resonance imaging (MRI) system designed for preclinical research applications. It operates at a field strength of 7 Tesla and has a bore size of 16 cm, allowing for the imaging of small laboratory animals. The system is capable of providing high-resolution images and advanced imaging techniques for various preclinical studies.
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Lab products found in correlation
2 protocols using pharmascan 7t 16 cm system
1
Multimodal Neuroimaging of Intrathecal Tracer Kinetics
2
High-Field MRI Brain Imaging Protocol
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MRI data were acquired using a Bruker Pharmascan 7T/16cm system (Ettlingen, Germany) with a gradient coil insert (internal diameter = 90 mm, 300 mT/m) and a four-channel phased-array surface receive coil used for brain
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