Agilent 5973 organic mass spectrometer

JEOL-ECX 500 NMR spectrometer (JEOL, Tokyo, Japan) was used to analyse the NMR spectral (¹H NMR and ¹³C NMR) at room temperature using TMS as an internal standard and DMSO-d₆ as the solvent. Elemental analysis was performed on the Elementar Vario-III CHN analyser (Elementar, Hanau, Germany). Mass spectral were conducted on the Agilent 5973 organic mass spectrometer (Agilent Technologies, Palo Alto, CA, USA). Melting points were determined on the XT-4 binocular microscope (Beijing Tech Instrument Co., China). All commercial reagents and solvents were used as they did not require any purification before use.

The melting points of the products were determined on an XT-4 binocular microscope (Beijing Tech Instrument Co., Beijing, China) and were not corrected. The IR spectra were recorded on a Bruker VECTOR 22 spectrometer (Bruker Optics Inc. Billerica, MA, USA) in KBr disk. ¹H NMR and ¹³C NMR (solvent DMSO-d₆) spectral analyses were performed on a JEOL-ECX 500 NMR spectrometer (JEOL Ltd., Tokyo, Japan) at room temperature using tetramethylsilane (TMS) as an internal standard. Elemental analysis was performed on an Elementar Vario-III CHN analyzer (Elementar, Frankfurt, Germany). Mass spectral studies were conducted on an Agilent 5973 organic mass spectrometer (Agilent Technologies, Palo Alto, Canada). Microwave experiments were carried out using a CEM Discover Labmate microwave apparatus (Discover^®LabMate instrument, CEM Corporate, Matthews, NC, USA). Analytical TLC was performed on silica gel GF254 (200–300 mesh). All solvents were dried by standard methods in advance and distilled before use.