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Romidepsin

Manufactured by Focus Biomolecules
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Romidepsin is a histone deacetylase (HDAC) inhibitor, a class of compounds that modulate gene expression by altering the acetylation state of histones and other proteins. It is a cyclic peptide that has been used in research applications to study the effects of HDAC inhibition on cellular processes and disease models.

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Lab products found in correlation

Pacritinib, by Merck Group (2 mentions) Brefeldin a, by MedChemExpress (2 mentions)

2 protocols using romidepsin

1

Macrocycle Compounds Acquisition Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
All the macrocycle compounds are commercially available. Brefeldin A was purchased from MedChemExpress, romidepsin and troleandomycin from Focus Biomolecules, simeprevir and paritaprevir from Invivochem, and pacritinib from Sigma Aldrich.
Danelius E., Bu G., Wieske H, & Gonen T. (2023). MicroED as a powerful tool for structure determination of macrocyclic drug compounds directly from their powder formulations. bioRxiv.
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2

Macrocycle Compound Acquisition Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
All of the macrocycle compounds
are commercially available. Brefeldin
A was purchased from MedChemExpress, romidepsin and troleandomycin
from Focus Biomolecules, simeprevir and paritaprevir from Invivochem,
and pacritinib from Sigma-Aldrich.
Danelius E., Bu G., Wieske L.H, & Gonen T. (2023). MicroED as a Powerful Tool for Structure Determination of Macrocyclic Drug Compounds Directly from Their Powder Formulations. ACS Chemical Biology, 18(12), 2582-2589.
+ Open protocol
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