Hyaluronic acid sodium salt

Manufactured by ABCR

Sourced in Germany

Hyaluronic acid sodium salt is a naturally occurring polysaccharide that is commonly used in various laboratory applications. It functions as a viscosity-increasing agent and lubricant, and is often utilized in cell culture, tissue engineering, and pharmaceutical formulations.

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3 protocols using hyaluronic acid sodium salt

Hyaluronic Acid Biomaterial Synthesis

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5 kDa HA (4659 Da Hyaluronic acid sodium salt) was purchased from abcr GmbH, 100 kDa HA (80–100 kDa Hyaluronic acid sodium salt) was purchased from abcr GmbH, 470 kDa HA (intrinsic viscosity 1.02 m³/kg) and 810 kDa HA (intrinsic viscosity 1.51 m³/kg) were purchased from CONTIPRO, 1700 kDa HA was purchased from HTL Biotechnology and provided by Qventis GmbH. Dithiothreitol, methacrylic anhydride, tetraethyl orthosilicate (TEOS), cetyltrimethylammonium bromide (CTAB), (3-Mercaptopropyl)trimethoxysilane and Hyaluronidase type IV-S from bovine testes were purchased from Sigma Aldrich. HeLa cells were purchased from ATCC. High glucose DMEM, AlamarBlue®, Phalloidin Alexa Fluor™ 647 and DAPI (4′,6-Diamidino-2-Phenylindole, Dihydrochloride) were purchased from Thermofischer.

Piantanida E., Boškoski I., Quero G., Gallo C., Zhang Y., Fiorillo C., Arena V., Costamagna G., Perretta S, & De Cola L. (2021). Nanocomposite hyaluronic acid-based hydrogel for the treatment of esophageal fistulas. Materials Today Bio, 10, 100109.

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Ciprofloxacin-PVP Antimicrobial Wound Dressing

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Polyvinylpyrrolidone (PVP; MW = 360,000), monohydrochloride monohydrate free ciprofloxacin (Cipro; ≥98.0% HPLC; MW = 331.34), glycerol, acetic acid (AcOH; ≥99.7%), and phosphate buffered saline (PBS) solution (pH 7.4) were bought from Sigma-Aldrich (St. Louis, MO, USA). Hyaluronic acid sodium salt (HA; MW = 350,000) was bought from Abcr (Karlsruhe, Germany). All the purchased products were used as received. A Milli-Q Advantage A10 ultrapure water purification system was utilized for the deionized water. Neomercurocromo^®® (Neo), a commercialized cutaneous antiseptic product, produced by Laboratorio Farmaceutiche Specialità Igienico Terapeutiche S.I.T. s.r.l. (Pavia, Italy), was bought in a local pharmacy. Further details regarding Neo composition and its application can be found in Contardi et al. [41 (link)].

Contardi M., Summa M., Picone P., Brancato O.R., Di Carlo M., Bertorelli R, & Athanassiou A. (2022). Evaluation of a Multifunctional Polyvinylpyrrolidone/Hyaluronic Acid-Based Bilayer Film Patch with Anti-Inflammatory Properties as an Enhancer of the Wound Healing Process. Pharmaceutics, 14(3), 483.

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Fabrication of Antioxidant Hydrogel Scaffolds

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Pure zein powder, rutin hydrate, alginic acid sodium salt, poly(ethylene glycol), 2,2-diphenyl-1-picrylhydrazyl free radical (DPPH˙), 2,20-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), and potassium persulfate (K₂S₂O₈) were provided by Sigma-Aldrich (St Louis, USA) and used as received without further purification. Granular calcium chloride (CaCl₂) was purchased from Merck KGaA (Darmstadt, Germany). Hyaluronic acid sodium salt (MW = 350 000) was purchased from ABCR (Karlsruhe, Germany). Commercial stainless steel (SS) springs (L = 15.7 mm, D = 2.75 mm) and flat sheets (316L SS, 500 mm × 300 mm × 0.5 mm) were purchased from RS Component (Milan, Italy). Dulbecco's phosphate buffered saline (PBS) and ethanol (≥99.8%) were purchased from Sigma-Aldrich (St Louis, USA), while deionized water (ddH₂O) was supplied by a Milli-Q Integral purification system (Millipore, Bedford, USA).

Lenzuni M., Suarato G., Miele D., Carzino R., Ruggeri M., Bertorelli R., Sandri G, & Athanassiou A. (2021). Development of biodegradable zein-based bilayer coatings for drug-eluting stents. RSC Advances, 11(39), 24345-24358.

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