Verio 3 tesla mri scanner

All MRI data was obtained using the Siemens Verio 3Tesla MRI Scanner with an 8-channel head-coil. In addition, the rs-fMRI images were obtained using the following parameters: 240 time points, repetition time (TR) = 2,000 ms, echo time (TE) = 25 ms, flip angle = 90°, number of slices = 36, slice thickness = 4 mm, spatial resolution = 3.75 × 3.75 × 4 mm³, acquisition matrix = 64 × 64, and field of view (FOV) = 240 × 240 mm². Additionally, the 3D magnetization-prepared rapid gradient echo (MP-RAGE) were acquired to get the T1-weighted images with the following data parameters: TR = 1,900 ms, TE = 2.48 ms, slice thickness = 1 mm, FA = 90°, FOV = 256 × 256 mm, gap = 0 mm, and number of slices = 176. Moreover, the ASL data was obtained using the following parameters: TI1 = 600 ms, TI2 = 1.6 s, flip angle = 90°, number of slices = 27, slice thickness = 4.0 mm, TR = 4 s, TE = 12 ms, FOV = 220 × 220 mm², and matrix size = 64 × 64.

All subjects underwent MRI scanning performed on a Verio 3 Tesla MRI scanner (Siemens Medical, Erlangen, Germany), yielding T1- and diffusion-weighted images (DWIs) obtained using a unique protocol across, as follows: (1) T1 weighted images: 3D magnetization-prepared rapid gradient echo (MPRAGE) sequences with parameters: repetition time (TR) = 2250 ms, echo time (TE) = 4.18 ms, flip angle = 6°, FOV = 256 × 256 mm, matrix size = 256 × 256, slice thickness: 1 mm and 192 sagittal slices; (2) DWI: twice-refocused, single-shot echo planar sequence with diffusion weightings b-value = 0, 1000, and 2000 s/mm² applied along 30 non-collinear directions. Other imaging parameters were: TR = 8500 ms, TE = 98 ms, field of view = 222 × 222 mm, matrix size = 74 × 74, bandwidth = 1324 Hz/pixel, parallel imaging factor of 2, no partial Fourier encoding, number of excitations (NEX) = 10 for b = 0 s/mm², and 1 for b = 1000, 2000 s/mm², and 40 axial slices each 3 mm thick (no gap).