The MRI was performed on a Siemens Trio 3.0T system (Siemens, Erlangen, Germany). The axial T2WI, coronal T2WI, sagittal T2WI, T1WI, and fat suppression T2WI images were acquired using the fast spin echo sequence. After the abnormal region was found, DCE-MRI was acquired using a FLASH 3D VIBE sequence, with TR=4.1ms, TE=1.5 ms, flip angle=10°, matrix=256×192, FOV (field of view) =250mm×250 mm, slice thickness=3mm. A total of 16 DCE time frames were taken covering the DCE time period of 120~168 s. The contrast agent, gadopentetate dimeglumine (Gd-DTPA), at a dose of 0.1 mmol/kg was injected after one pre-contrast frame was taken, with the speed of 2 ml/s.
PET/CT was performed using a Siemens Biograph 64 PET/CT system (Siemens, Erlangen, Germany) with 52-rings PET, and 64-row spiral CT. All patients were fasted before the examination, and blood glucose levels were in the range of 4.4–9.3 mmol/L. All patients underwent whole-body PET/CT conventional imaging 60 minutes after injection of 3.7–4.5 MBq/kg 18F-FDG. A 64-row spiral CT scan was performed with voltage of 140 kV, current of 100 mA, and a slice thickness of 3 mm. PET imaging was done using the 3D mode acquisition with iterative construction. The scan time was 8 minutes for the head scan, and 3 minutes per bed for the body scan from calvaria to the upper part of the femur.
PET/CT was performed using a Siemens Biograph 64 PET/CT system (Siemens, Erlangen, Germany) with 52-rings PET, and 64-row spiral CT. All patients were fasted before the examination, and blood glucose levels were in the range of 4.4–9.3 mmol/L. All patients underwent whole-body PET/CT conventional imaging 60 minutes after injection of 3.7–4.5 MBq/kg 18F-FDG. A 64-row spiral CT scan was performed with voltage of 140 kV, current of 100 mA, and a slice thickness of 3 mm. PET imaging was done using the 3D mode acquisition with iterative construction. The scan time was 8 minutes for the head scan, and 3 minutes per bed for the body scan from calvaria to the upper part of the femur.