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Vyntus cpx unit

Manufactured by Vyaire Medical
Sourced in Germany

The Vyntus CPX is a medical device used for cardiopulmonary exercise testing. It is designed to measure and analyze respiratory and cardiovascular parameters during physical activity. The Vyntus CPX provides objective data to healthcare professionals for the assessment of a patient's exercise capacity and overall health.

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3 protocols using vyntus cpx unit

1

Incremental Treadmill Exercise Test for Peak V'O2

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Peak exercise capacity defined as peak oxygen consumption (peak VO2) was determined using an incremental treadmill (Woodway PPS 55 Med; Woodway, Weil am Rhein, Germany) exercise test according to a modified Bruce protocol [29 (link)] using a Vyntus CPX unit powered by SentrySuite software (Vyaire Medical GmbH, Hoechberg, Germany). Speed and elevation increased every minute, starting from a slow walking phase, until the participants reached their maximum intensity level. The test was stopped when the participant indicated severe exhaustion or was unable to continue due to EILO symptoms, preferably supported by a respiratory exchange ratio (RER) exceeding 1.05 or heart rate exceeding 95% of maximally predicted [30 (link)]. Airflow and gas exchange parameters was measured breath-by-breath through a modified face mask (Hans Rudolph Inc., Kansas City, MO, USA) and averaged over 10 s. The cardiopulmonary exercise test (CPET) parameters recorded at maximal exhaustion are listed in table 1.
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2

Incremental Treadmill Test Protocol

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An incremental treadmill (Woodway PPS 55 Med, Weil am Rhein, Germany) test was applied, using a pre-set modified Bruce protocol [25 (link)]. Speed and elevation were gradually increased every 60 s from an initial slow walking phase. A facemask (Hans Rudolph Inc., Kansas City, MO, USA) connected the patient to a Vyntus CPX unit powered by SentrySuite software (Vyaire Medical GmbH, Leibnizstrasse, Hoechberg, Germany). After baseline variables were established, subjects ran to exhaustion. Parameters of gas exchange and airflow were measured breath-by-breath and averaged over 30 s.
The test was considered successful when the subjects indicated exhaustion, preferably supported by a plateau in VO2 and/or the heart rate (HR) response. Duration and completed treadmill distance were recorded. VO2, carbon dioxide output (VCO2), tidal volume (VT), respiratory rate (RR) and HR were measured directly, while minute ventilation (VE) was calculated from VT and RR.
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3

Treadmill Exercise Test for VO2peak Evaluation

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Peak exercise capacity was determined using a computerized incremental treadmill (Woodway PPS 55 Med, Weil am Rhein, Germany) exercise test according to a modified Bruce protocol (19 (link)) using a Vyntus CPX unit powered by SentrySuite software (Vyaire Medical GmbH, Hoechberg, Germany). Speed and elevation were increased every 90 s from an initial slow-walking phase. The test was stopped when the subject indicated severe exhaustion, preferably supported by a respiratory exchange ratio (RER) exceeding 1.05 or heart rate exceeding 95% of predicted maximal heart rate (20 (link)).
Variables of gas exchange and airflow were measured breath by breath and averaged over 10 s. The highest values for oxygen uptake determined during the last 60 s were recorded as peak values (VO2peak). VO2peak was reported as ml/kg/min and as the percentage of predicted using reference equations from a large sample of Norwegian subjects of relevant age (21 (link)). Exercise performance was described by the completed distance (meters) on the treadmill. The percentage inspiratory time to total time in a respiratory cycle (Ti/Ttot%) was used to describe the breathing pattern. Breathing reserve was the difference between maximal voluntary ventilation (FEV1 x 35) and peak minute ventilation reported as the percentage of maximal voluntary ventilation.
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