The radiographic system Allura Xper FD20/10 (PHILIPS Medical Systems, the Netherlands) was used for the angiographic imaging at a rate of 15 frames/s. The contrast medium was injected at a stable rate of approximately 4 mL/s using a pump. The 2D-QCA was performed using the Angiogram QCA software (Allura Xper FD20/10; PHILIPS Medical Systems, The Netherlands). A coronary pressure wire (St. Jude Medical, St. Paul, Minnesota, USA) was used to calculate FFR with the pressure sensor positioned at 2–3 cm distal to the target lesion of the coronary artery. Before placement, the pressure wire was calibrated and equalized, and intravenous adenosine triphosphate concentration was 150–180 g/kg/min to induce maximum hyperemia of the coronary microvascular system. Simultaneously, the distal and proximal coronary artery pressures at the pressure sensor (Pd) and coronary ostium (Pa) were recorded. The pressure sensor was then pulled back to the proximal end to assess or correct pressure drift. The FFR was determined by dividing Pd by Pa. Further analysis was performed at the core laboratory using all ICA and FFR data. Thus, a standardized radiographic system, pressure wire, and software were used, and strict protocols were followed for data collection and analysis to ensure accuracy and reliability [33 (link)].
Allura xper fd20 10
Manufactured by Philips
The Allura Xper FD20/10 is a cardiovascular X-ray imaging system designed by Philips. It provides high-quality fluoroscopic and digital imaging capabilities for diagnostic and interventional procedures.
Automatically generated - may contain errors
Lab products found in correlation
Iodixanol, by GE Healthcare (1 mentions)
Coronary pressure wire, by Abbott (1 mentions)
4f fogarty embolectomy catheter, by Edwards Lifesciences (1 mentions)
Xtravision, by Philips (1 mentions)
Imeron 300, by Bracco (1 mentions)
Iplan cranial, by Brainlab (1 mentions)
Ingenia 3.0t, by Philips (1 mentions)
8 protocols using allura xper fd20 10
1
Standardized Angiographic Imaging and FFR Measurement
2
Coronary Angiography and Quantitative Analysis
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
ICA was performed using the X-ray system (Allura Xper FD20/10; PHILIPS Medical Systems, the Netherlands). These angiographic images were recorded at 15 frames/s. The contrast medium was injected manually with a forceful and stable injection or by the pump at a rate of ~4 ml/s. 2D-QCA was conducted by using angiogram vendor-integrated QCA software (Allura Xper FD20/10; PHILIPS Medical Systems, the Netherlands).
3
Optimizing Angiography System Performance
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All procedures were performed on the Allura Xper FD20/10 system (Philips Healthcare, Eindhoven, The Netherlands) by an experienced team of neuroradiologists. As we are a university hospital, young neuroradiologists were regularly involved in the interventions in addition to a neuroradiologist with many years of angiography experience. The X‑ray unit was equipped with an automatic exposure control system. The frame rate frequently used in the pulsed fluoroscopy mode was 1 pulse/s. The focus-to-skin distance varied from 60 to 70 cm. The Allura Xper system had one 20-inch detector with a maximum field of view (FOV) of 48 cm and one 10-inch detector with a maximum FOV of 25 cm. The minimum inherent filtration (at 75 kV) of the X‑ray tube/collimator was 2.5 mm Al. Besides a wedge filter of 1 mm brass (CuZn37 R‑019; 22 mm Al equivalent at 75 kV), an additional filter (0.9 mm Cu + 1.0 mm Al) was set, depending on the beam-limiting device. To test the performance and stability of the system over time, regular quality checks were performed during maintenance visits.
4
Vertebral Artery Catheter Angiography
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All patients underwent catheter angiography on an Allura Xper FD20/10 (Philips Healthcare), Artis Zee Biplane, or Artis Zeego angiography unit (Siemens Healthcare). Catheter angiography on anteroposterior and lateral projections, and oblique projections as necessary were performed after placement of a diagnostic catheter in the V1 segment of the vertebral artery in question with injection of 5 ml of contrast (Iodixanol, GE healthcare) at a rate of 3 ml per second at 300 Pa pressure. Then, 3D angiography was performed while injecting a total 18 ml contrast at a rate of 3 ml per second at 300 Pa pressure.
5
Rabbit Model of Atherosclerosis Induction
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Male New Zealand White rabbits (2.5–3 months old), purchased from Charles River Laboratories (Wilmington, MA) underwent double balloon injury of the thoracic and abdominal aorta to induce atherosclerosis. Denudation was performed by introducing a 4F-Fogarty embolectomy catheter (Edwards Lifesciences, Irvine, CA) under fluoroscopic guidance using a Philips Allura Xper FD20/10, Philips Healthcare (Best, The Netherlands). The catheter was introduced into the femoral artery, and the balloon was inflated to either 1 atm or 2 atm, depending on the degree of atherosclerosis desired. Surgery was performed under anaesthesia with intramuscular Ketamine (35 mg kg−1) and Xylazine (5 mg kg−1) injection. To further accelerate plaque progression, animals were fed a high cholesterol diet (Research Diets) enriched initially with 0.3% for 8 weeks, and subsequently 0.15% for 8 weeks, and was continued until study termination approximately 4 months after diet first began. The procedure was performed 2 weeks after start of high-cholesterol diet and repeated on the contralateral leg 4 weeks later. Male New Zealand White rabbits fed a standard chow diet served as controls. Experiments were performed in accordance with protocols approved by the Institutional Animal Care and Use Committees of the Icahn School of Medicine at Mount Sinai, NYC.
6
Digital Subtraction Angiography Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Digital subtraction angiography (DSA) was performed under local anesthesia on a biplane flat panel DSA unit (Allura Xper FD 20/10, Philips, Best, The Netherlands) via a femoral access. 3D-RA was performed with a selective contrast injection of 20 ml Imeron 300 (Iomeprol, Bracco Imaging, Milan, Italy) in the ipsilateral internal carotid artery at a flow rate of 2 ml/s. The dataset was transferred to a dedicated workstation (XtraVision, Philips, Best, The Netherlands) and reconstructed with a voxel size of 0.27 × 0.27 × 0.27 mm3.
7
3D Imaging Analysis of AVM Patients
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Image data, including 3D-RA, 3D-rotational venography (RV), comported tomography (CT), and magnetic resonance imaging (MRI), was obtained from AVM patients. Threedimensional-RA and RV were performed with a C-arm angiography unit (Allura XperFD 20/10; Philips Medical Systems, Best, the Netherlands). The C-arm rotated through 240° at 55°/s and obtained 120 images on a 17-in. FOV during contrast injection. MRI was performed with a 3.0-T system for the head (Ingenia 3.0T; Philips Healthcare, Andover, MA.). Fluid-attenuated inversion recovery (FLAIR) in MRI was acquired with an eight-channel head coil. CT was done with a 64-section CT scanner (Aquilion; Toshiba Medical Systems, Tokyo, Japan). The slice thickness was 1 mm.
Image data was coded in digital imaging and communication in medicine (DICOM) format and was imported to the two different imaging applications. In this study, we used iPLAN cranial (BrainLab, Germany) and Avizo (Visualization Science Group, Bordeaux, France) for 3D image reconstruction using a previously reported method [1, 2] . In iPLAN, the 3D model was constructed with a volume rendering method with autosegmentation, whereas Avizo used a hybrid method combining surface-and volume-rendering methods, and manual segmentation was used to distinguish the small anatomical structures, such as the feeding arteries, from surrounding noise.
Image data was coded in digital imaging and communication in medicine (DICOM) format and was imported to the two different imaging applications. In this study, we used iPLAN cranial (BrainLab, Germany) and Avizo (Visualization Science Group, Bordeaux, France) for 3D image reconstruction using a previously reported method [1, 2] . In iPLAN, the 3D model was constructed with a volume rendering method with autosegmentation, whereas Avizo used a hybrid method combining surface-and volume-rendering methods, and manual segmentation was used to distinguish the small anatomical structures, such as the feeding arteries, from surrounding noise.
8
Subarachnoid Hemorrhage Induction and Imaging
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Occipital regions of anesthetized animals (positioned supine, 90º left-rotated heads) were sterilized (75% alcohol). Contiguous occipital-cervical areas were epilated and heads bent for puncture of dura mater under local anesthesia (1% lidocaine) and with uoroscopic guidance, using a 23-G spinal needle to pierce atlanto-occipital membranes. To identify subarachnoid space, cisternal delivery of mixed contrast medium and normal saline (1:1 ratio) commenced at rst sign of cerebrospinal uid (CSF). A modicum (~2 cc) of CSF was then withdrawn, instilling a 2-cc sampling of femoral arterial blood as replacement via spinal needle. Thereafter, animal heads were lowered (~30º) and allowed 20 min of stabilization. 12, 14 Angiography equipment (Allura Xper FD20/10; Philips Healthcare, Amsterdam, Netherlands) used for Xper computed tomography (CT) enabled veri cation of SAH.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!