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Sigma scanner

Manufactured by GE Healthcare
Sourced in United States

The Sigma scanner is a medical imaging device designed for diagnostic use. It utilizes advanced scanning technology to capture high-quality images for medical professionals to analyze. The core function of the Sigma scanner is to provide detailed visual data to support clinical decision-making.

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8 protocols using sigma scanner

1

Resting-State fMRI Acquisition Protocol

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Functional images were acquired using the same 3.0T GE Sigma scanner by using a circular polarized birdcage head coil. After a localization scan, the resting-state functional images were obtained with a gradient-recalled echo-planar imaging sequence. The parameters were as follows: repetition time (TR)=2000 ms, echo time (TE)=30 ms, field of view (FOV)=240×240 mm2, data matrix=64×64, flip angle (FA)=90°, 30 slices, slice thickness=5 mm, scanner time=6 min 50 s. Subjects lay supine and were asked to remain motionless, relax with their eyes closed, and without thinking.
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2

Functional MRI Acquisition Protocol

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For each individual, 266 volumes were acquired during a scanning session from a 1.5-T GE Sigma scanner (General Electric Medical Systems, Milwaukee, WI, USA). A gradient echo-planar imaging (EPI) sequence, depicting the blood oxygenation level-dependent (BOLD) contrast was used. Each volume contained 16 axial planes acquired with the following parameters: repetition time (TR) = 2000 ms, echo time (TE) = 20 ms, flip angle = 70°, section thickness = 7 mm, section skip = 0.7 mm, and in-plane resolution = 3 × 3 mm. To avert T1 saturation effects, the 10 initial volumes were removed.
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3

Functional MRI Study of Brain Imaging

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MRI scanning was done using a 3.0 T GE Sigma scanner at the High‐Field Magnetic Resonance Brain Imaging Key Laboratory at the University of Electronic Science and Technology of China, Chengdu, China. We acquired functional MRI images using a gradient echo planar imaging (EPI) sequence. The scanning parameters were the following: 190 EPI volumes per block; TR = 2000 ms; TE = 30 ms; FA = 90°; FOV = 240 mm; matrix size = 64 × 64; voxel size = 3.75 × 3.75 × 3 mm3; 43 slices. We also acquired a high‐resolution, whole‐brain structural T1‐weighted image with a magnetization‐prepared gradient echo sequence. The scanning parameters were the following: TR = 1900 ms; TE = 2.26 ms; thickness, 1 mm; sagittal field of view, 256 × 256 mm2; flip angle, 9°; matrix, 256 × 256 × 176; voxel size, 1 × 1 × 1 mm3.
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4

In Vitro MRI Contrast Agent Evaluation

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In vitro MRI test was performed at 3.0T on a Sigma scanner (GE, Milwaukee, WI, USA) according to the method published previously by our group.24 (link) The T1-weighted MR images of VPDG and the Magnevist were obtained, respectively. MR images were taken at a series of Gd concentrations at 40, 20, 10, 5, and 1 μmol/L. For the measurement of T1 relaxivity, the samples were tested by using T1-weighted pulse sequences which held the time of echo (TE) constant at 15 ms while varying the time of repetition (TR) to TR-167, TR-300, TR-600, TR-900, TR-1500, and TR-2500 ms, respectively. The signal intensity of the samples was measured on each of the images, and the T1 relaxivity was calculated for each concentration of the different contrast agents, respectively. Quantitative T1 relaxation maps were reconstructed from data sets for six different relaxation times using function software at a workstation.
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5

Multimodal Neuroimaging: Spiral MRI and Acoustic

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Image data were acquired on a 1.5 T GE Sigma scanner, using a 13-interleaf spiral gradient echo pulse sequence (TR = 6.004 ms, FOV = 200 × 200 mm, flip angle = 15º) and a custom 4-channel head and neck receiver coil. Pixel density in the midsagittal plane (5 mm slice thickness) was 84 × 84 (2.38 × 2.38 mm2). Image data were acquired at a rate of 12.8 frames per second and reconstructed at 23.79 frames per second using a sliding window technique. Acoustic data were recorded inside the scanner at 20 kHz simultaneously with MRI image acquisition, and noise reduced using the custom protocol described in Bresch et al. (2006) (link).
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6

Brain MRI Imaging Protocol

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All brain images were collected using a 1.5 T GE Sigma scanner located within Hokkaido University, School of Medicine. All the subjects participated in scanning examinations that lasted approximately 30–40 minutes. T1 anatomical images of the head (spin echo, repetition time [TR] 500 ms, echo time [TE] 14 ms, flip angle 90°, field of view 24 cm ×24 cm, matrix size 256×256, slice thickness 4 mm, interslice gap 1 mm, 20 interleaved axial slices) and T2-star [T2*] functional images (gradient echo planar imaging [EPI], TR 3,000 ms, TE 40 ms, flip angle 90°, field of view 24 cm ×24 cm, matrix size 64×64, slice thickness 4 mm, interslice gap 1 mm, 20 interleaved axial slices) were acquired during each of the examinations. The slice positions were chosen to cover almost the entire brain, including the entire occipital pole and the ventral surface of the temporal lobes.
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7

Brain Imaging Protocol on 1.5T MRI

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Brain imaging was conducted on a 1.5 Tesla Sigma scanner (General Electric, Milwaukee, WI, USA) equipped with a standard head coil. Twenty-four contiguous, gradient-echo echo planar images, sensitive to BOLD contrast, parallel to the AC-PC, were acquired using a T2* weighted gradient-echo EPI sequence (TR 4 sec, TE 4 sec, FOV 28 cm, image matrix 642, flip angle 90°, slide thickness 4 mm, and cubic 4.375 mm3 isotropic voxels). High-resolution T1-weighted images were also acquired (TR 4.50 sec, TE 9 msec, FOV 24 cm, matrix 2562, and slice thickness 1.5 mm).
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8

BOLD Imaging of Vigilant ADHD Participants

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Imaging was conducted using a 3 Tesla GE Sigma Scanner with an eight channel head coil to acquire gradient echo T2*-weighted echo-planar images with blood oxygenation level-dependent (BOLD) contrast. Twenty-nine slices were acquired, covering the whole brain, with 4 mm thickness, 2×2 mm2 in-plane voxel resolution, repetition time (TR) = 2.3 ms, echo time (TE) = 27 ms and a flip angle α = 90°. T1-weighted structural images were acquired with TR = 7.8 ms, TE = 3.2 ms, α = 20°, matrix size = 256×256, slice thickness = 1 mm, voxel size = 1×1×1 mm. Right before the MRI acquisition, all participants were vigilant as assessed by the Stanford Sleepiness Scale (MADHD = 2.12±0.60, MHC = 2.35±0.70; p = 0.301, d = −0.35).
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